Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Sheryl G. Beck"'
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 8 (2014)
It has been well established that modulating serotonin (5-HT) levels in humans and animals affects perception and response to social threats, however the circuit mechanisms that control 5-HT output during social interaction are not well understood. A
Externí odkaz:
https://doaj.org/article/a52247b130f148ffb93f3f11d5033f98
Autor:
Douglas G. McMahon, W. Clay Spencer, LaTasha K Crawford, Benjamin D. Rood, Noah H. Green, Caryne Craige, Paul J. Gresch, Sheryl G. Beck, Evan S. Deneris, Steven C. Wyler
Publikováno v:
The Journal of Neuroscience. 36:1758-1774
Newborn neurons enter an extended maturation stage, during which they acquire excitability characteristics crucial for development of presynaptic and postsynaptic connectivity. In contrast to earlier specification programs, little is known about the
Autor:
Jennifer Da, Sheryl G. Beck, Aseem Upadhyay, Collin Challis, Preetika Gupta, Olivier Berton, Avin Veerakumar
Publikováno v:
Biological Psychiatry. 76:203-212
Background Cortical deep brain stimulation (DBS) is a promising therapeutic option for treatment-refractory depression, but its mode of action remains enigmatic. Serotonin (5-HT) systems are engaged indirectly by ventromedial prefrontal cortex (vmPFC
Autor:
Kaitlin Campbell, Zachary P. Spangler, Sheryl G. Beck, David A. Piel, Benjamin D. Rood, Lyngine H. Calizo
Publikováno v:
The Journal of Neuroscience. 34:4809-4821
Trauma during early life is a major risk factor for the development of anxiety disorders and suggests that the developing brain may be particularly sensitive to perturbation. Increased vulnerability most likely involves altering neural circuits invol
Autor:
Guanxia Zhan, Sigrid C. Veasey, David A. Piel, Yanpeng Li, Lori Panossian, Sheryl G. Beck, Seema Bhatnagar, Yan Zhu, Yu-Ting Chou, Jing Zhang, Polina Fenik
Publikováno v:
Sleep. 37:51-64
STUDY OBJECTIVES Delayed hypercapnic arousals may occur in obstructive sleep apnea. The impaired arousal response is expected to promote more pronounced oxyhemoglobin desaturations. We hypothesized that long-term sleep fragmentation (SF) results in i
Autor:
Avin Veerakumar, Janette Boulden, Patrick Matthias, Jeanine Jochems, Sarah L. Teegarden, Tess Petersen, Michael Chan, Julie Espallergues, Sheryl G. Beck, Olivier Berton, Evan S. Deneris, Chang-Gyu Hahn, Irwin Lucki, Collin Challis
Publikováno v:
The Journal of Neuroscience. 32:4400-4416
Genetic variations in certain components of the glucocorticoid receptor (GR) chaperone complex have been associated with the development of stress-related affective disorders and individual variability in therapeutic responses to antidepressants. Mec
Publikováno v:
European Journal of Neuroscience. 34:1794-1806
Characterization of glutamatergic input to dorsal raphe (DR) serotonin (5-HT) neurons is crucial for understanding how the glutamate and 5-HT systems interact in psychiatric disorders. Markers of glutamatergic terminals, vGlut1, 2 and 3, reflect inpu
Autor:
Willem Heydendael, Sandra Luz, Vikram Iyer, Sheryl G. Beck, Seema Bhatnagar, David A. Piel, Kanika Sharma
Publikováno v:
Endocrinology. 152:4738-4752
Orexins/hypocretins heavily innervate the posterior division of the paraventricular nucleus of the thalamus (pPVT), which expresses both orexin receptor types. The pPVT is important for adaptations to repeated stress, particularly the ability to faci
Autor:
Caryne Craige, Bruno P. Guiard, Alex Dranovsky, H. F. Kung, E. D. Leonardo, Jesse W. Richardson-Jones, T. H. Nguyen, Denis J. David, Rene Hen, Alain M. Gardier, Sheryl G. Beck
Publikováno v:
The Journal of Neuroscience. 31:6008-6018
Identifying the factors contributing to the etiology of anxiety and depression is critical for the development of more efficacious therapies. Serotonin (5-HT) is intimately linked to both disorders. The inhibitory serotonin-1A (5-HT1A) receptor exist
Autor:
Amy R. Brooks-Kayal, Guojun Zhang, Teresa Walsh, Adaure Akanwa, Lynn G. Kirby, Julia C. Lemos, Sheryl G. Beck
Publikováno v:
Neuropsychopharmacology. 36:721-734
Major depression is a debilitating psychiatric disease that may be precipitated by a dysregulation of stress neurocircuitry caused by chronic or severe stress exposure. Moreover, hyperresponsivity to stressors correlates with depressed mood and may c