Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Shervin Tabrizi"'
Autor:
Dylan Kotliar, Adrian Veres, M Aurel Nagy, Shervin Tabrizi, Eran Hodis, Douglas A Melton, Pardis C Sabeti
Publikováno v:
eLife, Vol 8 (2019)
Identifying gene expression programs underlying both cell-type identity and cellular activities (e.g. life-cycle processes, responses to environmental cues) is crucial for understanding the organization of cells and tissues. Although single-cell RNA-
Externí odkaz:
https://doaj.org/article/53e0519e4b954b8bbbf464efc1b123ac
Autor:
Jeffrey G Shaffer, Donald S Grant, John S Schieffelin, Matt L Boisen, Augustine Goba, Jessica N Hartnett, Danielle C Levy, Rachael E Yenni, Lina M Moses, Mohammed Fullah, Mambo Momoh, Mbalu Fonnie, Richard Fonnie, Lansana Kanneh, Veronica J Koroma, Kandeh Kargbo, Darin Ottomassathien, Ivana J Muncy, Abigail B Jones, Megan M Illick, Peter C Kulakosky, Allyson M Haislip, Christopher M Bishop, Deborah H Elliot, Bethany L Brown, Hu Zhu, Kathryn M Hastie, Kristian G Andersen, Stephen K Gire, Shervin Tabrizi, Ridhi Tariyal, Mathew Stremlau, Alex Matschiner, Darryl B Sampey, Jennifer S Spence, Robert W Cross, Joan B Geisbert, Onikepe A Folarin, Christian T Happi, Kelly R Pitts, F Jon Geske, Thomas W Geisbert, Erica Ollmann Saphire, James E Robinson, Russell B Wilson, Pardis C Sabeti, Lee A Henderson, S Humarr Khan, Daniel G Bausch, Luis M Branco, Robert F Garry, Viral Hemorrhagic Fever Consortium
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 3, p e2748 (2014)
BACKGROUND:Lassa fever (LF), an often-fatal hemorrhagic disease caused by Lassa virus (LASV), is a major public health threat in West Africa. When the violent civil conflict in Sierra Leone (1991 to 2002) ended, an international consortium assisted i
Externí odkaz:
https://doaj.org/article/55ad3c3b355949c08ef8d3693670c434
Autor:
Jin H. Bae, Ruolin Liu, Eugenia Roberts, Erica Nguyen, Shervin Tabrizi, Justin Rhoades, Timothy Blewett, Kan Xiong, Gregory Gydush, Douglas Shea, Zhenyi An, Sahil Patel, Ju Cheng, Sainetra Sridhar, Mei Hong Liu, Emilie Lassen, Anne-Bine Skytte, Marta Grońska-Pęski, Jonathan E. Shoag, Gilad D. Evrony, Heather A. Parsons, Erica L. Mayer, G. Mike Makrigiorgos, Todd R. Golub, Viktor A. Adalsteinsson
Publikováno v:
Nature Genetics. 55:871-879
Detecting mutations from single DNA molecules is crucial in many fields but challenging. Next-generation sequencing (NGS) affords tremendous throughput but cannot directly sequence double-stranded DNA molecules (‘single duplexes’) to discern the
Autor:
Shervin Tabrizi, Carmen Martin-Alonso, Kan Xiong, Timothy Blewett, Sainetra Sridhar, Zhenyi An, Sahil Patel, Sergio Rodriguez-Aponte, Christopher A. Naranjo, Shih-Ting Wang, Douglas Shea, Todd R. Golub, Sangeeta N. Bhatia, Viktor Adalsteinsson, J. Christopher Love
Publikováno v:
bioRxiv
Blood-based, or “liquid,” biopsies enable minimally invasive diagnostics but have limits on sensitivity due to scarce cell-free DNA (cfDNA). Improvements to sensitivity have primarily relied on enhancing sequencing technologyex vivo. Here, we sou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78f801620377ed2460cada89da0da0f1
https://doi.org/10.1101/2023.01.13.523947
https://doi.org/10.1101/2023.01.13.523947
Autor:
Carmen Martin-Alonso, Shervin Tabrizi, Kan Xiong, Timothy Blewett, Sahil Patel, Zhenyi An, Sainetra Sridhar, Ahmet Bekdemir, Douglas Shea, Ava P. Amini, Shih-Ting Wang, Jesse Kirkpatrick, Justin Rhoades, Todd R. Golub, J. Christopher Love, Viktor A. Adalsteinsson, Sangeeta N. Bhatia
Publikováno v:
bioRxiv
Liquid biopsies are enabling minimally invasive monitoring and molecular profiling of diseases across medicine, but their sensitivity remains limited by the scarcity of cell-free DNA (cfDNA) in blood. Here, we report an intravenous priming agent that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c820d25086601d81af5b242564adf344
https://doi.org/10.1101/2023.01.13.524003
https://doi.org/10.1101/2023.01.13.524003
Publikováno v:
Breast Cancer Research and Treatment. 191:229-241
Purpose Immune checkpoint inhibition (ICI) has demonstrated clinically significant efficacy when combined with chemotherapy in triple negative breast cancer (TNBC). Although many patients derived benefit, others do not respond to immunotherapy, there
Autor:
Shervin Tabrizi, Carmen Martin-Alonso, Kan Xiong, Timothy Blewett, Sainetra Sridhar, Zhenyi An, Sahil Patel, Sergio Rodriguez-Aponte, Christopher Naranjo, Douglas Shea, Todd Golub, Sangeeta N. Bhatia, Viktor A. Adalsteinsson, J. Christopher Love
Publikováno v:
Cancer Research. 83:3371-3371
Liquid biopsies using cell-free DNA (cfDNA) enable non-invasive detection and characterization of disease. Advances in sequencing methods have significantly improved the performance of liquid biopsies. Yet, despite these advances, sensitivity remains
Autor:
Carmen Martin-Alonso, Shervin Tabrizi, Kan Xiong, Ahmet Bekdemir Bekdemir, Sahil Patel, Zhenyi An, Timothy Blewett, Sainetra Sridhar, Douglas Shea, Ava Amini, Jesse D. Kirkpatrick, Jin Bae, Eugenia Roberts, Ruolin Liu, Justin Rhoades, Todd Golub, J. Christopher Love, Viktor A. Adalsteinsson, Sangeeta N. Bhatia
Publikováno v:
Cancer Prevention Research. 16:PR007-PR007
Liquid biopsy measurements, such as analysis of circulating tumor DNA (ctDNA) shed by cancer cells, have garnered significant attention for their potential to empower the field of precision oncology. Given that ctDNA tests could enable minimally inva
Autor:
Shyam K. Tanguturi, Rifaquat Rahman, Brian M. Alexander, Steffen Ventz, Daniel N. Cagney, Patrick Y. Wen, Shervin Tabrizi, Geoffrey Fell, Lorenzo Trippa
Publikováno v:
Neuro-Oncology
Background During the ongoing COVID-19 pandemic, contact with the health care system for cancer treatment can increase risk of infection and associated mortality. Treatment recommendations must consider this risk for elderly and vulnerable cancer pat
Autor:
Viktor A. Adalsteinsson, Shervin Tabrizi, Todd R. Golub, Blewett T, Douglas Shea, An Z, Patel S, Justin Rhoades, Ruolin Liu, Greg Gydush, Makrigiorgos Gm, Jin H. Bae, Erica Nguyen, Kan Xiong
Detecting mutations as rare as a single molecule is crucial in many fields such as cancer diagnostics and aging research but remains challenging. Third generation sequencers can read a double-stranded DNA molecule (a ‘single duplex’) in whole to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa653026c31a9dece27b41ec91c8c1dd
https://doi.org/10.1101/2021.06.11.448110
https://doi.org/10.1101/2021.06.11.448110