Zobrazeno 1 - 10
of 244
pro vyhledávání: '"Shervin, Assassi"'
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background One of the most promising approaches for early and more precise disease prediction and diagnosis is through the inclusion of proteomics data augmented with clinical data. Clinical proteomics data is often characterized by its high
Externí odkaz:
https://doaj.org/article/48f4ba0c5eee4a879611cc1b57ef34d4
Autor:
Elizabeth R. Volkmann, Holly Wilhalme, Shervin Assassi, Grace Hyun J. Kim, Jonathan Goldin, Masataka Kuwana, Donald P. Tashkin, Michael D. Roth
Publikováno v:
ACR Open Rheumatology, Vol 5, Iss 10, Pp 547-555 (2023)
Objective Progressive pulmonary fibrosis (PPF) is the leading cause of death in systemic sclerosis (SSc). This study aimed to develop a clinical prediction nomogram using clinical and biological data to assess risk of PPF among patients receiving tre
Externí odkaz:
https://doaj.org/article/c6aa75ec170c44a7ad6960cb9f59e514
Autor:
Santiago Sanchez, Aaron K McDowell-Sanchez, Sharaz B Al-Meerani, Juan D Cala-Garcia, Alan R Waich Cohen, Scott A Ochsner, Neil J McKenna, Lindsay J Celada, Minghua Wu, Shervin Assassi, Ivan O Rosas, Konstantin Tsoyi
Publikováno v:
PLoS ONE, Vol 19, Iss 9, p e0306624 (2024)
Systemic sclerosis (SSc), also known as scleroderma, is an autoimmune-driven connective tissue disorder that results in fibrosis of the skin and internal organs such as the lung. Fibroblasts are known as the main effector cells involved in the progre
Externí odkaz:
https://doaj.org/article/418a366eedcd467a86c9f8d2de5350c8
Autor:
Toby M Maher, Michael Kreuter, Vincent Cottin, Daniel Wachtlin, Anna-Maria Hoffmann-Vold, Marlies S Wijsenbeek, Fernando J Martinez, Shervin Assassi, Luca Richeldi, Arata Azuma, Justin M Oldham, Claudia Valenzuela, Carl Coeck, Christina Schlecker, Florian Voss
Publikováno v:
BMJ Open Respiratory Research, Vol 10, Iss 1 (2023)
Introduction Progressive pulmonary fibrosis (PPF) includes any diagnosis of progressive fibrotic interstitial lung disease (ILD) other than idiopathic pulmonary fibrosis (IPF). However, disease progression appears comparable between PPF and IPF, sugg
Externí odkaz:
https://doaj.org/article/0431457e10d0437986592042ea5048ab
Autor:
Mark Hwang, Shervin Assassi, Jim Zheng, Jessica Castillo, Reyna Chavez, Kamala Vanarsa, Chandra Mohan, John Reveille
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-10 (2023)
Abstract Background We sought to discover serum biomarkers of ankylosing spondylitis (AS) for diagnosis and monitoring disease activity. Methods We studied biologic-treatment-naïve AS and healthy control (HC) patients’ sera. Eighty samples matched
Externí odkaz:
https://doaj.org/article/7a500f80967d405c989c3e4c475c3459
Autor:
Chiara Bellocchi, Xuan Wang, Marka A. Lyons, Maurizio Marchini, Maurizio Lorini, Vincenzo Carbonelli, Nicola Montano, Shervin Assassi, Lorenzo Beretta
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
ObjectiveThis study aims to characterize differential expressed pathways (DEP) in subjects with preclinical systemic sclerosis (PreSSc) characterized uniquely by Raynaud phenomenon, specific autoantibodies, and/or capillaroscopy positive for sclerode
Externí odkaz:
https://doaj.org/article/e77ff6c47f4542f5a191193ac158ecf7
Autor:
Chiara Bellocchi, Shervin Assassi, Marka Lyons, Maurizio Marchini, Chandra Mohan, Alessandro Santaniello, Lorenzo Beretta
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-10 (2023)
Abstract Background The study of molecular mechanisms characterizing disease progression may be relevant to get insights into systemic sclerosis (SSc) pathogenesis and to intercept patients at very early stage. We aimed at investigating the proteomic
Externí odkaz:
https://doaj.org/article/3092a359489a4357858b0bd39a9f75b8
Autor:
Martin Kerick, Marialbert Acosta-Herrera, Carmen Pilar Simeón-Aznar, José Luis Callejas, Shervin Assassi, International SSc Group, Susanna M. Proudman, Mandana Nikpour, Australian Scleroderma Interest Group (ASIG), PRECISESADS Clinical Consortium, Nicolas Hunzelmann, Gianluca Moroncini, Jeska K. de Vries-Bouwstra, Gisela Orozco, Anne Barton, Ariane L. Herrick, Chikashi Terao, Yannick Allanore, Carmen Fonseca, Marta Eugenia Alarcón-Riquelme, Timothy R. D. J. Radstake, Lorenzo Beretta, Christopher P. Denton, Maureen D. Mayes, Javier Martin
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-12 (2022)
Abstract Copy number (CN) polymorphisms of complement C4 play distinct roles in many conditions, including immune-mediated diseases. We investigated the association of C4 CN with systemic sclerosis (SSc) risk. Imputed total C4, C4A, C4B, and HERV-K C
Externí odkaz:
https://doaj.org/article/bc1f849f269a49ad8114bddf64958fc9
Autor:
Shervin Assassi, Oliver Distler, Yannick Allanore, Takashi Ogura, John Varga, Serena Vettori, Bruno Crestani, Florian Voss, Margarida Alves, Susanne Stowasser, Toby M. Maher, SENSCIS trial investigators
Publikováno v:
ACR Open Rheumatology, Vol 4, Iss 10, Pp 837-844 (2022)
Objective In the SENSCIS trial, participants with systemic sclerosis‐associated interstitial lung disease (SSc‐ILD) were randomized to receive nintedanib or placebo until the last participant reached week 52 but for 100 weeks or less. Nintedanib
Externí odkaz:
https://doaj.org/article/b8ec770a71194c15809a1a37bce8b2cd
Autor:
Robyn K. Wojeck, Mitchell R. Knisely, Donald E. Bailey, Tamara J. Somers, Linda Kwakkenbos, Marie-Eve Carrier, Warren R. Nielson, Susan J. Bartlett, Vanessa L. Malcarne, Marie Hudson, Brooke Levis, Andrea Benedetti, Luc Mouthon, Brett D. Thombs, Susan G. Silva, Claire E. Adams, Richard S. Henry, Catherine Fortuné, Karen Gottesman, Geneviève Guillot, Laura K. Hummers, Amanda Lawrie-Jones, Maureen D. Mayes, Michelle Richard, Maureen Sauvé, Shervin Assassi, Ghassan El-Baalbaki, Kim Fligelstone, Tracy Frech, Amy Gietzen, Daphna Harel, Monique Hinchcliff, Sindhu R. Johnson, Maggie Larche, Catarina Leite, Christelle Nguyen, Karen Nielsen, Janet Pope, François Rannou, Tatiana Sofia Rodriguez-Reyna, Anne A. Schouffoer, Maria E. Suarez-Almazor, Christian Agard, Nassim Ait Abdallah, Marc André, Elana J. Bernstein, Sabine Berthier, Lyne Bissonnette, Alessandra Bruns, Patricia Carreira, Marion Casadevall, Benjamin Chaigne, Lorinda Chung, Benjamin Crichi, Christopher Denton, Robyn Domsic, James V. Dunne, Bertrand Dunogue, Regina Fare, Dominique Farge-Bancel, Paul R. Fortin, Jessica Gordon, Brigitte Granel-Rey, Aurélien Guffroy, Genevieve Gyger, Eric Hachulla, Sabrina Hoa, Alena Ikic, Suzanne Kafaja, Nader Khalidi, Kimberly Lakin, Marc Lambert, David Launay, Yvonne C. Lee, Hélène Maillard, Nancy Maltez, Joanne Manning, Isabelle Marie, Maria Martin Lopez, Thierry Martin, Ariel Masetto, François Maurier, Arsene Mekinian, Sheila Melchor Díaz, Mandana Nikpour, Louis Olagne, Vincent Poindron, Susanna Proudman, Alexis Régent, Sébastien Rivière, David Robinson, Esther Rodríguez Almazar, Sophie Roux, Perrine Smets, Vincent Sobanski, Robert Spiera, Virginia Steen, Evelyn Sutton, Carter Thorne, John Varga, Pearce Wilcox, Mara Cañedo Ayala, Vanessa Cook, Sophie Hu, Bianca Matthews, Elsa-Lynn Nassar, Marieke Alexandra Neyer, Julia Nordlund, Sabrina Provencher
Publikováno v:
EClinicalMedicine, Vol 62, Iss , Pp 102104- (2023)
Summary: Background: Systemic sclerosis is a heterogenous disease in which little is known about patterns of patient-reported symptom clusters. We aimed to identify classes of individuals with similar anxiety, depression, fatigue, sleep disturbance,
Externí odkaz:
https://doaj.org/article/3c82e788a0114b59adfd3e08502ac600