Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sherryline Jogie-Brahim"'
Autor:
Sherryline Jogie-Brahim, Yong-Chul Lee, Youngman Oh, Jinfeng Han, Dae Yeol Lee, Liam J. Murphy, Aki Harada
Publikováno v:
Journal of Biological Chemistry. 286:17898-17909
Insulin-like growth factor-binding protein-3 (IGFBP-3) is a multifunctional protein known for modulating mitogenic and metabolic actions of IGFs as well as exerting a variety of biological actions not involving IGFs. Here, we show that IGFBP-3 blocks
Publikováno v:
Endocrine Reviews. 30:417-437
The IGF system plays critical roles in somatic growth in an endocrine fashion (somatomedin hypothesis) as well as proliferation and differentiation of normal and malignant cells in a paracrine/autocrine fashion. IGFBP-3 is known to modulate the actio
Publikováno v:
Analytical Letters. 40:2799-2820
Affinity chromatographic methods for purifying antibodies are reviewed. Topics reviewed include (a) the matrices used in the preparation of the affinity supports; (b) the chemistries commonly used to attach affinity ligands directly on hydroxyl‐car
Publikováno v:
The Journal of Immunology. 179:1353-1361
The dramatic effects of the anti-IgE mAb omalizumab to lower free IgE levels and FcεRI levels on basophils contrast with more modest clinical effects. Accordingly, whether IgE modulates FcεRI levels and FcεRI-dependent mediator release in vitro on
Publikováno v:
Journal of Allergy and Clinical Immunology. 113:1086-1092
Background α and β-Tryptase levels in serum are clinical tools for the evaluation of systemic anaphylaxis and systemic mastocytosis. Basophils and mast cells are known to produce these proteins. Objective The current study examines the effect of th
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 80(3)
IGFBP-3 is a tumor suppressor whose expression is frequently suppressed in lung cancer. NNK, the most potent tobacco carcinogen, enhanced cell proliferation of BEAS-2B normal lung epithelial cells and concomitantly suppressed IGFBP-3 expression throu
Publikováno v:
Cancer letters. 307(2)
Nuclear factor-kappaB (NF-κB) is constitutively activated in a variety of human cancers including prostate cancer and involved in tumorigenesis, tumor progression and chemo-resistance. Insulin-like growth factor-binding protein-3 (IGFBP-3) is a pote
Publikováno v:
Expert review of proteomics. 2(1)
Early investigations into the insulin-like growth factor (IGF)-independent actions of insulin-like growth factor-binding protein (IGFBP)-3 have implicated a large array of signaling proteins with links to cell cycle control and apoptosis. However, th
Autor:
Sherryline, Jogie-Brahim, Hae-Ki, Min, Yoshihiro, Fukuoka, Han-Zhang, Xia, Lawrence B, Schwartz
Publikováno v:
The Journal of allergy and clinical immunology. 113(6)
Alpha and beta-tryptase levels in serum are clinical tools for the evaluation of systemic anaphylaxis and systemic mastocytosis. Basophils and mast cells are known to produce these proteins.The current study examines the effect of the alpha,beta-tryp
Publikováno v:
Journal of Allergy and Clinical Immunology. 119:S53