Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Sherry T. Hikita"'
Autor:
Amanda-Jayne Carr, Anthony A Vugler, Sherry T Hikita, Jean M Lawrence, Carlos Gias, Li Li Chen, David E Buchholz, Ahmad Ahmado, Ma'ayan Semo, Matthew J K Smart, Shazeen Hasan, Lyndon da Cruz, Lincoln V Johnson, Dennis O Clegg, Pete J Coffey
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8152 (2009)
Transformation of somatic cells with a set of embryonic transcription factors produces cells with the pluripotent properties of embryonic stem cells (ESCs). These induced pluripotent stem (iPS) cells have the potential to differentiate into any cell
Externí odkaz:
https://doaj.org/article/4af9d242b75a470aa5f97c662d3b9acc
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3312 (2008)
The MUC1 protein is aberrantly expressed on an estimated 75% of all human solid tumor cancers. We recently reported that a transmembrane cleavage product, MUC1*, is the predominant form of the protein on cancer cells [1]. Further, our evidence indica
Externí odkaz:
https://doaj.org/article/b1d8418bda5a4f838a108612e5215ff0
Autor:
Chih-Min Lin, Amir H. Kashani, Lincoln V. Johnson, Mark S. Humayun, Debbie Mitra, Sherry T. Hikita, Robert L. Avery, Hani Salehi-Had, Biju B. Thomas, Jane Lebkowski, Dennis O. Clegg, Danhong Zhu, Britney O Pennington, David R. Hinton, Wei Dang, Firas M. Rahhal
Publikováno v:
Science Translational Medicine. 10
Retinal pigment epithelium (RPE) dysfunction and loss are a hallmark of non-neovascular age-related macular degeneration (NNAMD). Without the RPE, a majority of overlying photoreceptors ultimately degenerate, leading to severe, progressive vision los
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6446d1a7a8e8cb340de9c1596f8857c7
https://doi.org/10.1126/scitranslmed.aao4097
https://doi.org/10.1126/scitranslmed.aao4097
Publikováno v:
Pennington, BO; Clegg, DO; Melkoumian, ZK; & Hikita, ST. (2015). Defined culture of human embryonic stem cells and xeno-free derivation of retinal pigmented epithelial cells on a novel, synthetic substrate. Stem Cells Translational Medicine, 4(2), 165-177. doi: 10.5966/sctm.2014-0179. UC Santa Barbara: Retrieved from: http://www.escholarship.org/uc/item/5nk066gd
Stem cells translational medicine, vol 4, iss 2
Stem cells translational medicine, vol 4, iss 2
Age-related macular degeneration (AMD), a leading cause of blindness, is characterized by the death of the retinal pigmented epithelium (RPE), which is a monolayer posterior to the retina that supports the photoreceptors. Human embryonic stem cells (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e7de3a8da3b789cb228650c3ccf3a5
https://doi.org/10.5966/sctm.2014-0179
https://doi.org/10.5966/sctm.2014-0179
Autor:
David E. Buchholz, Lincoln V. Johnson, Teisha J. Rowland, Sherry T. Hikita, Alison J. Blaschke, Dennis O. Clegg
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 7:642-653
A potential application of human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) is the generation of retinal pigmented epithelium (RPE) to treat age-related macular degeneration (AMD), a common but incurable retinal disease.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a2b24900fc54e8250135d292fc1f27d
https://doi.org/10.1002/term.1458
https://doi.org/10.1002/term.1458
Autor:
Fang Wang, H. Haeberle, Lincoln V. Johnson, Mark S. Humayun, Eckart Bertelmann, Uwe Pleyer, Frank Tost, Bo Lu, Bruno Diniz, Seiji Yanai, Manoel Odorico de Moraes, Yi-Qiao Xing, Keizo Minamino, Wei Zhou, Kanji Takahashi, David R. Hinton, Anna-Karina B. Maier, Druck Reinhardt Druck Basel, Yuichiro Imai, S. Walter, Lídia Moreira Lima, Padmaja B. Thomas, Mariana Zaira M.L. Ribeiro, Laura Liu, Joao Crispim Moraes Lima Ribeiro, W. Hofmüller, Dennis O. Clegg, Zhi-Qing Wu, Yan-Ning Yang, M. Seibold, Rico Grossjohann, Yuntao Hu, Maria Elisabete Amaral de Moraes, Matthias K. J. Klamann, Chieko Shima, Francisco Vagnaldo Fechine, Satz Mengensatzproduktion, Johannes Gonnermann, Clemens Jürgens, Susumu Ikehara, Ashish Ahuja, Sherry T. Hikita, W. Behrens-Baumann, Ramiro Ribeiro, Yasushi Adachi, I. Tammer, Biju B. Thomas, T. Wecke, K. Tintelnot, Eliezer J. Barreiro, Yu-Chong Tai, Mitsuhiko Okigaki, Danhong Zhu, Julian Philip Klein, Nágila M.P.S. Ricardo, Ming Shi, Antonia M. Joussen
Publikováno v:
Ophthalmic Research. 48:I-IV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08ced0f530098284fb94316dfa2f14e8
https://doi.org/10.1159/000337110
https://doi.org/10.1159/000337110
Autor:
Laura Liu, Yuntao Hu, Padmaja B. Thomas, Danhong Zhu, Bruno Diniz, Lincoln V. Johnson, Mark S. Humayun, Yu-Chong Tai, Dennis O. Clegg, David R. Hinton, Bo Lu, Ashish Ahuja, Sherry T. Hikita, Ramiro Ribeiro, Biju B. Thomas
Publikováno v:
Ophthalmic Research. 48:186-191
Objective: To evaluate the feasibility of a new technique for the implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium (RPE) cells into the subretinal space of retina-degenerate Royal College of Surgeon (RCS) r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a8407aee1b1c6c7869c37e440ff41c0
https://doi.org/10.1159/000338749
https://doi.org/10.1159/000338749
Autor:
Sherry T. Hikita, Dennis O. Clegg, Amy M. Friedrich, Lincoln V. Johnson, Teisha J. Rowland, Cassidy R. Hinman, David E. Buchholz
Publikováno v:
Stem Cells. 27:2427-2434
Human induced pluripotent stem cells (iPSCs) have great promise for cellular therapy, but it is unclear if they have the same potential as human embryonic stem cells (hESCs) to differentiate into specialized cell types. Ocular cells such as the retin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc7245228da92a3ee9bfbf306464e00b
https://doi.org/10.1002/stem.189
https://doi.org/10.1002/stem.189
Autor:
Sherry T. Hikita, Lisa Kinney, Susan A.L. Jacques, Erin C. Tolhurst, Kevin L. Wingerd, Sergiu T. Leu, Derek Wiswell, Dennis O. Clegg, Nichol L. Goodman, Jan L. Pring, David Y. Jackson
Publikováno v:
Developmental Biology. 276:416-430
In the retina, integrins in the beta1 family have been shown to be important in many phases of neuronal development, particularly neuroblast migration and axon outgrowth. However, the functions of specific integrin heterodimers are not well defined.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b61687f1ce9e00ffa9a017ac1030370
https://doi.org/10.1016/j.ydbio.2004.09.003
https://doi.org/10.1016/j.ydbio.2004.09.003
Publikováno v:
Clegg, DO; Wingerd, KL; Hikita, ST; & Tolhurst, EC. (2003). Integrins in the development, function and dysfunction of the nervous system. Frontiers in Bioscience, 8. UC Santa Barbara: Retrieved from: http://www.escholarship.org/uc/item/90h3m29x
Frontiers in bioscience : a journal and virtual library, vol 8, iss 4
Frontiers in bioscience : a journal and virtual library, vol 8, iss 4
Integrin receptors mediate cell-cell and cell-extracellular matrix (ECM) interactions in many different cell types, including neuronal cells. Earlier studies have shown a clear role for integrins in axon extension and cell adhesion/migration in CNS i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1386d210843346cc969d97d8dca246a8
https://doi.org/10.2741/1020
https://doi.org/10.2741/1020