Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sherry Lam"'
Autor:
Marie A. Labouesse, Arturo Torres-Herraez, Muhammad O. Chohan, Joseph M. Villarin, Julia Greenwald, Xiaoxiao Sun, Mysarah Zahran, Alice Tang, Sherry Lam, Jeremy Veenstra-VanderWeele, Clay O. Lacefield, Jordi Bonaventura, Michael Michaelides, C. Savio Chan, Ofer Yizhar, Christoph Kellendonk
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract In the classical model of the basal ganglia, direct pathway striatal projection neurons (dSPNs) send projections to the substantia nigra (SNr) and entopeduncular nucleus to regulate motor function. Recent studies have re-established that dSP
Externí odkaz:
https://doaj.org/article/81d980c17c3448e59ac7e2551e221f37
Synaptic Zn2+ potentiates the effects of cocaine on striatal dopamine neurotransmission and behavior
Autor:
Juan L. Gomez, Jordi Bonaventura, Jacqueline Keighron, Kelsey M. Wright, Dondre L. Marable, Lionel A. Rodriguez, Sherry Lam, Meghan L. Carlton, Randall J. Ellis, Chloe J. Jordan, Guo-hua Bi, Oscar Solis, Marco Pignatelli, Michael J. Bannon, Zheng-Xiong Xi, Gianluigi Tanda, Michael Michaelides
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Cocaine binds to the dopamine (DA) transporter (DAT) to regulate cocaine reward and seeking behavior. Zinc (Zn2+) also binds to the DAT, but the in vivo relevance of this interaction is unknown. We found that Zn2+ concentrations in postmorte
Externí odkaz:
https://doaj.org/article/7c2c5e8de1754235a1d3f93bf616dd57
Autor:
Jordi Bonaventura, Mark A. G. Eldridge, Feng Hu, Juan L. Gomez, Marta Sanchez-Soto, Ara M. Abramyan, Sherry Lam, Matthew A. Boehm, Christina Ruiz, Mitchell R. Farrell, Andrea Moreno, Islam Mustafa Galal Faress, Niels Andersen, John Y. Lin, Ruin Moaddel, Patrick J. Morris, Lei Shi, David R. Sibley, Stephen V. Mahler, Sadegh Nabavi, Martin G. Pomper, Antonello Bonci, Andrew G. Horti, Barry J. Richmond, Michael Michaelides
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) are a powerful tool for neuroscience, but the standard DREADD ligand, CNO, has significant drawbacks. Here the authors report two novel high-potency DREADD ligands and a novel DREAD
Externí odkaz:
https://doaj.org/article/61041765c18b4742add3c9f64f5d7580
Autor:
Emilya Ventriglia, Arianna Rizzo, Juan L. Gomez, Jacob Friedman, Sherry Lam, Oscar Solís, Rana Rais, Jordi Bonaventura, Michael Michaelides
Publikováno v:
Neuropsychopharmacology. 48:831-842
Mu opioid receptor (MOR) agonists comprise the most effective analgesics, but their therapeutic utility is limited by adverse effects. One approach for limiting such effects has been to develop "biased" MOR agonists that show preference for activatin
Autor:
Marie Labouesse, Arturo Torres-Herraez, Muhammad Chohan, Joseph Villarin, Julia Greenwald, Xiaoxiao Sun, Mysarah Zahran, Alice Tang, Sherry Lam, Jeremy Veenstra-VanderWeele, Clay Lacefield, Jordi Bonaventura, Michael Michaelides, Savio Chan, Ofer Yizhar, Christoph Kellendonk
In the classical model of the basal ganglia, direct pathway striatal projection neurons (dSPNs) send projections to the substantia nigra (SNr) and entopeduncular nucleus to regulate motor function. Recent studies have re-established that dSPNs also p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::616089ede81b09b0cffd0c5cfbea02f9
https://doi.org/10.21203/rs.3.rs-2524816/v1
https://doi.org/10.21203/rs.3.rs-2524816/v1
Autor:
Jordi Bonaventura, Sherry Lam, Meghan Carlton, Matthew Boehm, Juan L. Gomez, Oscar Solís, Marta Sánchez-Soto, Patrick J. Morris, Ida Fredriksson, Craig J. Thomas, David R. Sibley, Yavin Shaham, Carlos A. Zarate, Michael Michaelides
Publikováno v:
Molecular Psychiatry. 27:1863-1865
Autor:
Jordi Bonaventura, Juan L. Gomez, Meghan L. Carlton, Sherry Lam, Marta Sanchez-Soto, Patrick J. Morris, Ruin Moaddel, Hye Jin Kang, Panos Zanos, Todd D. Gould, Craig J. Thomas, David R. Sibley, Carlos A. Zarate, Michael Michaelides
Publikováno v:
Mol Psychiatry
The off-label use of racemic ketamine and the FDA approval of (S)-ketamine are promising developments for the treatment of depression. Nevertheless, racemic ketamine and (S)-ketamine are controlled substances with known abuse potential and their use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40bae031142560fd647aa3a8a7cc11f6
https://europepmc.org/articles/PMC10013843/
https://europepmc.org/articles/PMC10013843/
Autor:
Jordi Bonaventura, Sherry Lam, Meghan Carlton, Matthew Boehm, Juan L. Gomez, Oscar Solís, Marta Sánchez-Soto, Patrick J. Morris, Ida Fredriksson, Craig J. Thomas, David R. Sibley, Yavin Shaham, Carlos A. Zarate, Michael Michaelides
Publikováno v:
Molecular Psychiatry.
Autor:
Matthew A. Boehm, Patrick J. Morris, Marta Sánchez-Soto, Michael Michaelides, Juan Gómez, Jordi Bonaventura, Oscar Solis, Carlos A. Zarate, Sherry Lam, Ida Fredriksson, Craig J. Thomas, Yavin Shaham, David R. Sibley, Meghan L. Carlton
Publikováno v:
Molecular Psychiatry. 26:6704-6722
Ketamine, a racemic mixture of (S)-ketamine and (R)-ketamine enantiomers, has been used as an anesthetic, analgesic and more recently, as an antidepressant. However, ketamine has known abuse liability (the tendency of a drug to be used in non-medical
Synaptic Zn2+ potentiates the effects of cocaine on striatal dopamine neurotransmission and behavior
Autor:
Dondre L. Marable, Kelsey M. Wright, Michael J. Bannon, Lionel A. Rodriguez, Zheng-Xiong Xi, Jordi Bonaventura, Juan Gómez, Marco Pignatelli, Guo Hua Bi, Randall J. Ellis, Sherry Lam, Oscar Solis, Michael Michaelides, Gianluigi Tanda, Jacqueline D. Keighron, Meghan L. Carlton, Chloe J. Jordan
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Translational Psychiatry, Vol 11, Iss 1, Pp 1-15 (2021)
Translational Psychiatry
Universidad de Barcelona
Translational Psychiatry, Vol 11, Iss 1, Pp 1-15 (2021)
Translational Psychiatry
Cocaine binds to the dopamine (DA) transporter (DAT) to regulate cocaine reward and seeking behavior. Zinc (Zn2+) also binds to the DAT, but the in vivo relevance of this interaction is unknown. We found that Zn2+ concentrations in postmortem brain (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1b7660b944fbfa906b0ed1b4b25373
http://hdl.handle.net/2445/189285
http://hdl.handle.net/2445/189285