Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Sherry L. Spinelli"'
Autor:
J. Allen Bennett, Michael A. Mastrangelo, Sara K. Ture, Charles O. Smith, Shannon G. Loelius, Rachel A. Berg, Xu Shi, Ryan M. Burke, Sherry L. Spinelli, Scott J. Cameron, Thomas E. Carey, Paul S. Brookes, Robert E. Gerszten, Maria Sabater-Lleal, Paul S. de Vries, Jennifer E. Huffman, Nicholas L. Smith, Craig N. Morrell, Charles J. Lowenstein
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Genetic association studies have identified loci including the choline transporter SLC44A2 as a potential regulator of thrombosis. Here the authors report that loss of SLC44A2 impairs platelet activation and thrombosis in mice via a reduction of mito
Externí odkaz:
https://doaj.org/article/62b9f79769b2412ba271abefe8be6aa0
Autor:
Moritz eStolla, Majed A Refaai, Joanna M. Heal, Sherry L. Spinelli, Olivier eGARRAUD, Richard P. Phipps, Neil eBlumberg
Publikováno v:
Frontiers in Immunology, Vol 6 (2015)
Platelet transfusion has been a vital therapeutic approach in patients with hematologic malignancies for close to half a century. Randomized trials show that prophylactic platelet transfusions mitigate bleeding in patients with acute myeloid leukemia
Externí odkaz:
https://doaj.org/article/b76700dccc5d4a91894e302fb3d57a66
Autor:
Chad A. Hudson, Majed A. Refaai, Grace Conley, Sherry L. Spinelli, Hannah L McRae, Neil Blumberg, Craig N. Morrell, Richard P. Phipps
Publikováno v:
Transfusion. 60:1579-1589
Background Platelet transfusion is associated with logistical problems with the national storage guidelines of platelets. This results in decreased function in vivo as a result of the platelet storage lesion, and complications such as allergic or hem
Autor:
Katie L Lannan, Julie eSahler, Nina eKim, Sherry L Spinelli, Sanjay B Maggirwar, Olivier eGARRAUD, Fabrice eCOGNASSE, Neil eBlumberg, Richard P Phipps
Publikováno v:
Frontiers in Immunology, Vol 6 (2015)
Platelets are small anucleate blood cells derived from megakaryocytes. In addition to their pivotal roles in hemostasis, platelets are the smallest, yet most abundant, immune cell and regulate inflammation, immunity, and disease progression. Although
Externí odkaz:
https://doaj.org/article/087e2b0eeb2f48d2be12b96c16a2b0b2
Autor:
Sherry L. Spinelli, Majed A. Refaai, Anthony P. Pietropaoli, Neil Blumberg, Suzie A. Noronha, Kelly F. Henrichs, Jill M. Cholette, Richard P. Phipps
Publikováno v:
Vox Sanguinis. 114:325-329
BACKGROUND Normal saline has been the fluid of choice for resuscitation, rehydration and fluid replacement during plasma or red cell exchange/cytapheresis. There are increased concerns about its clinical effects and data showing it causes more haemol
Autor:
Sherry L. Spinelli, Jill M. Cholette, Richard P. Phipps, Kelly F. Henrichs, Anthony P. Pietropaoli, Neil Blumberg, Majed A. Refaai
Publikováno v:
Transfusion. 59:2007-2015
BACKGROUND Relationships between red blood cell (RBC) transfusion, circulating cell-free heme, and clinical outcomes in critically ill transfusion recipients are incompletely understood. The goal of this study was to determine whether total plasma he
Autor:
Paul S. de Vries, Sara Ture, Charles J. Lowenstein, Craig N. Morrell, J. Allen Bennett, Nicholas L. Smith, Sherry L. Spinelli, Ryan M. Burke, Xu Shi, Jennifer E. Huffman, Michael A. Mastrangelo, Robert E. Gerszten, Shannon G. Loelius, Charles O. Smith, Scott J. Cameron, Paul S. Brookes, Thomas E. Carey, Maria Sabater-Lleal, Rachel A. Berg
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
r-IIB SANT PAU: Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Institut dInvestigació Biomèdica Sant Pau (IIB Sant Pau)
Nature Communications
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
r-IIB SANT PAU: Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Institut dInvestigació Biomèdica Sant Pau (IIB Sant Pau)
Genetic factors contribute to the risk of thrombotic diseases. Recent genome wide association studies have identified genetic loci including SLC44A2 which may regulate thrombosis. Here we show that Slc44a2 controls platelet activation and thrombosis
Autor:
Richard P. Phipps, Jerard Seghatchian, Suzie A. Noronha, Majed A. Refaai, Neil Blumberg, Jill M. Cholette, Michael P. Eaton, Sherry L. Spinelli, Joanna M. Heal, Anthony P. Pietropaoli
Publikováno v:
Transfusion and Apheresis Science. 57:127-131
Crystalloid infusion is widely employed in patient care for volume replacement and resuscitation. In the United States the crystalloid of choice is often normal saline. Surgeons and anesthesiologists have long preferred buffered solutions such as Rin
Autor:
Richard P. Phipps, Neil Blumberg, Amy E. Schmidt, Sherry L. Spinelli, Anthony P. Pietropaoli, Joanna M. Heal, Patricia J. Sime, Majed A. Refaai, Jill M. Cholette
Publikováno v:
Transfusion Medicine Reviews. 31:252-257
Thrombocytopenia or receipt of antiplatelet drugs, with or without bleeding, is a common indication for platelet transfusions in the ICU. However, there is almost no evidence base for these practices other than expert opinion. Also common is use of p
Publikováno v:
Journal of Thrombosis and Haemostasis. 15:802-813
Essentials Specialized proresolving mediators (SPMs) promote the resolution of inflammation. This study sought to investigate the effects of SPMs on human platelet function. The SPM, Maresin 1, enhanced hemostatic, but suppressed inflammatory functio