Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Sherry L. Kurtz"'
Host Genetic Background Influences BCG-Induced Antibodies Cross-Reactive to SARS-CoV-2 Spike Protein
Autor:
Aubrey G. Specht, Melanie Ginese, Sherry L. Kurtz, Karen L. Elkins, Harrison Specht, Gillian Beamer
Publikováno v:
Vaccines, Vol 12, Iss 3, p 242 (2024)
Mycobacterium bovis Bacillus Calmette-Guérin (BCG) protects against childhood tuberculosis; and unlike most vaccines, BCG broadly impacts immunity to other pathogens and even some cancers. Early in the COVID-19 pandemic, epidemiological studies iden
Externí odkaz:
https://doaj.org/article/05f13eedece24cbe8c4ea3a53b6945d8
Autor:
Sherry L. Kurtz, Amy P. Rossi, Gillian L. Beamer, Dan M. Gatti, Igor Kramnik, Karen L. Elkins
Publikováno v:
mSphere, Vol 5, Iss 2 (2020)
ABSTRACT Many studies of Mycobacterium tuberculosis infection and immunity have used mouse models. However, outcomes of vaccination and challenge with M. tuberculosis in inbred mouse strains do not reflect the full range of outcomes seen in people. P
Externí odkaz:
https://doaj.org/article/cddfce89436a43de9a56f36b303402dc
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0249142 (2021)
CCR2 is the major chemokine receptor that regulates appropriate trafficking of inflammatory monocytes, but the role of this chemokine receptor and its ligands during primary and secondary infection with intracellular infections remains incompletely u
Externí odkaz:
https://doaj.org/article/40c254739e9d45658cb6084bc8db9235
Autor:
Roberto De Pascalis, Amy P Rossi, Lara Mittereder, Kazuyo Takeda, Adovi Akue, Sherry L Kurtz, Karen L Elkins
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237034 (2020)
Production of IFN-γ is a key innate immune mechanism that limits replication of intracellular bacteria such as Francisella tularensis (Ft) until adaptive immune responses develop. Previously, we demonstrated that the host cell types responsible for
Externí odkaz:
https://doaj.org/article/a2ed8fdb6e5040ad9e4817799e1499a2
Autor:
Specht, Aubrey, Kurtz, Sherry L. Kurtz, Elkins, Karen L. Elkins, Specht, Harrison, Beamer, Gillian
Data sets and analysis for BCG vaccination of Diversity Outbred mice induces cross-reactive antibodies to SARS-CoV-2 spike protein The Bacillus Calmette-Guérin (BCG) vaccine, the only vaccine against tuberculosis, induces cross-protection against pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aed6a6954f49cbd1b36009b25370d15
The Bacillus Calmette-Guérin (BCG) vaccine, the only vaccine against tuberculosis, induces cross-protection against pathogens unrelated to Mycobacterium, including viruses. Epidemiological studies have identified potential benefits of BCG vaccinatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc36db9542a98c316c7c8e9972c0cdba
https://doi.org/10.1101/2022.04.18.488640
https://doi.org/10.1101/2022.04.18.488640
Autor:
Karen L. Elkins, Amy P. Rossi, Kazuyo Takeda, Roberto De Pascalis, Sherry L. Kurtz, Adovi Akue, Lara Mittereder
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 8, p e0237034 (2020)
PLoS ONE, Vol 15, Iss 8, p e0237034 (2020)
Production of IFN-γ is a key innate immune mechanism that limits replication of intracellular bacteria such as Francisella tularensis (Ft) until adaptive immune responses develop. Previously, we demonstrated that the host cell types responsible for
Publikováno v:
mSphere, Vol 5, Iss 2, p e00097-20 (2020)
mSphere, Vol 5, Iss 2 (2020)
mSphere
mSphere, Vol 5, Iss 2 (2020)
mSphere
We vaccinated the Diversity Outbred (DO) population of mice with BCG, the only vaccine currently used to protect against tuberculosis, and then challenged them with M. tuberculosis by aerosol. We found that the BCG-vaccinated DO mouse population exhi
Autor:
Tina M. Parker, Linda B. Adams, Michelle H. Larsen, Karen A. Lacourciere, Liliana C. M. Salvador, Carly Kanipe, Alison Kraigsley, Travis Hartman, Michele A. Miller, Jacqueline M. Achkar, Richard T. Robinson, Sherry L. Kurtz, Kathryn M. Dupnik, Luanne Hall-Stoodley, John S. Spencer
Publikováno v:
Tuberculosis (Edinb)
Mycobacteria are important causes of disease in human and animal hosts. Diseases caused by mycobacteria include leprosy, tuberculosis (TB), nontuberculous mycobacteria (NTM) infections and Buruli Ulcer. To better understand and treat mycobacterial di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892eeba8516b16b1f4b6b5f9e2b96faa
https://europepmc.org/articles/PMC7428850/
https://europepmc.org/articles/PMC7428850/
Publikováno v:
Microbes and Infection. 18:758-767
Our laboratory has employed in vitro and in vivo mouse models based on Francisella tularensis Live Vaccine Strain (LVS)-induced protection to elucidate immune correlates for intracellular bacteria. Among the effectors found was GM-CSF, a pleiotropic