Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sherry L Winter"'
Autor:
Philip G Wong, Sherry L Winter, Elena Zaika, Thinh V Cao, Umut Oguz, John M Koomen, Joyce L Hamlin, Mark G Alexandrow
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17533 (2011)
Little is known about mammalian preRC stoichiometry, the number of preRCs on chromosomes, and how this relates to replicon size and usage. We show here that, on average, each 100-kb of the mammalian genome contains a preRC composed of approximately o
Externí odkaz:
https://doaj.org/article/de18e5b1d85143e8874f041b4eb79e3a
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5462 (2009)
BACKGROUND: Control of the onset of DNA synthesis in mammalian cells requires the coordinated assembly and activation of the pre-Replication Complex. In order to understand the regulatory events controlling preRC dynamics, we have investigated how th
Externí odkaz:
https://doaj.org/article/90af07b7cbf4499bbd3b7fadb8f35638
Publikováno v:
Molecular and Cellular Biology. 30:845-856
Understanding inhibitory mechanisms of transforming growth factor beta1 (TGF-beta1) has provided insight into cell cycle regulation and how TGF-beta1 sensitivity is lost during tumorigenesis. We show here that TGF-beta1 utilizes a previously unknown
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 9, Iss 10, Pp 797-800 (2007)
There is a growing body of evidence implicating aberrant circadian clock expression in the development of cancer. Based on our initial experiments identifying a putative interaction between BRCA1 and the clock proteins Per1 and Per2, as well as the r
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 523
Of critical importance to many of the events underlying transcriptional control of gene expression are modifications to core and linker histones that regulate the accessibility of trans-acting factors to the DNA substrate within the context of chroma
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5462 (2009)
PLoS ONE
PLoS ONE
BACKGROUND: Control of the onset of DNA synthesis in mammalian cells requires the coordinated assembly and activation of the pre-Replication Complex. In order to understand the regulatory events controlling preRC dynamics, we have investigated how th
Publikováno v:
Methods in Molecular Biology ISBN: 9781588298737
Of critical importance to many of the events underlying transcriptional control of gene expression are modifications to core and linker histones that regulate the accessibility of trans-acting factors to the DNA substrate within the context of chroma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1dcdd6eed12a7ce5da3ebc827dd4084f
https://doi.org/10.1007/978-1-59745-190-1_3
https://doi.org/10.1007/978-1-59745-190-1_3
Publikováno v:
Neoplasia (New York, N.Y.). 9(10)
There is a growing body of evidence implicating aberrant circadian clock expression in the development of cancer. Based on our initial experiments identifying a putative interaction between BRCA1 and the clock proteins Per1 and Per2, as well as the r
Publikováno v:
BMC Cancer, Vol 7, Iss 1, p 85 (2007)
BMC Cancer
BMC Cancer
Background The breast cancer susceptibility gene, BRCA1, is implicated in multiple cellular processes including DNA repair, the transactivation of genes, and the ubiquitination of proteins; however its precise functions remain to be fully understood.
Autor:
John M. Koomen, Umut Oguz, Thinh V. Cao, Mark G. Alexandrow, Philip Wong, Joyce L. Hamlin, Elena Zaika, Sherry L. Winter
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17533 (2011)
PLoS ONE
PLoS ONE
Little is known about mammalian preRC stoichiometry, the number of preRCs on chromosomes, and how this relates to replicon size and usage. We show here that, on average, each 100-kb of the mammalian genome contains a preRC composed of approximately o