Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Sherry G. Clendenon"'
Autor:
Priyom Adhyapok, Agnieszka M. Piatkowska, Michael J. Norman, Sherry G. Clendenon, Claudio D. Stern, James A. Glazier, Julio M. Belmonte
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102317- (2021)
Summary: Somitogenesis is often described using the clock-and-wavefront (CW) model, which does not explain how molecular signaling rearranges the pre-somitic mesoderm (PSM) cells into somites. Our scanning electron microscopy analysis of chicken embr
Externí odkaz:
https://doaj.org/article/ab64e35591024677a522afb7d13d7e5f
Autor:
Xiao Fu, James P Sluka, Sherry G Clendenon, Kenneth W Dunn, Zemin Wang, James E Klaunig, James A Glazier
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0198060 (2018)
Computational models of normal liver function and xenobiotic induced liver damage are increasingly being used to interpret in vitro and in vivo data and as an approach to the de novo prediction of the liver's response to xenobiotics. The microdosimet
Externí odkaz:
https://doaj.org/article/77faf0bce05e48aab4de960dd826f832
Autor:
Clark D. Wells, Kevin Lange, Abigail F. Thompson, Wei Min Xu, Sherry G. Clendenon, John S. Underwood, Peter Harris, Britney-Shea Herbert, James Glazier, Angela Wandinger-Ness, Robert L. Bacallao
Despite substantial progress in identifying and understanding causative mutations in autosomal dominant polycystic kidney disease (ADPKD), little is known about subsequent cellular events leading to cyst formation. In prior studies we reported that C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec54840b5215eacb007a0adf804cbaff
https://doi.org/10.1101/2022.03.01.482118
https://doi.org/10.1101/2022.03.01.482118
Autor:
James P Sluka, Xiao Fu, Maciej Swat, Julio M Belmonte, Alin Cosmanescu, Sherry G Clendenon, John F Wambaugh, James A Glazier
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162428 (2016)
We describe a multi-scale, liver-centric in silico modeling framework for acetaminophen pharmacology and metabolism. We focus on a computational model to characterize whole body uptake and clearance, liver transport and phase I and phase II metabolis
Externí odkaz:
https://doaj.org/article/16b20de816ff4c75b82958dcd34c4023
Autor:
Claudio D. Stern, Julio M. Belmonte, Michael J. Norman, Sherry G. Clendenon, James A. Glazier, Priyom Adhyapok, Agnieszka M. Piatkowska
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102317-(2021)
iScience
iScience
Summary Somitogenesis is often described using the clock-and-wavefront (CW) model, which does not explain how molecular signaling rearranges the pre-somitic mesoderm (PSM) cells into somites. Our scanning electron microscopy analysis of chicken embry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc0ca57a2f36c374aec850dc6e66f07f
http://www.sciencedirect.com/science/article/pii/S2589004221002856
http://www.sciencedirect.com/science/article/pii/S2589004221002856
Autor:
Sherry G. Clendenon, Michelle Martinez, Henry E. Mang, Kenneth W. Dunn, James P. Sluka, Zemin Wang, James E. Klaunig, James A. Glazier
Publikováno v:
Toxicology
Mitochondrial injury and depolarization are primary events in acetaminophen hepatotoxicity. Previous studies have shown that restoration of mitochondrial function in surviving hepatocytes, which is critical to recovery, is at least partially accompli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::376997d60b4b2efdd5e6cdd12ab77337
https://pubmed.ncbi.nlm.nih.gov/32315716
https://pubmed.ncbi.nlm.nih.gov/32315716
Autor:
Seth Winfree, James A. Glazier, Xiao Fu, James E. Klaunig, Sherry G. Clendenon, Henry Mang, Adele J. Filson, Jeffrey L. Clendenon, James P. Sluka, Kenneth W. Dunn, Michelle Martinez, Robert A. Von Hoene
Publikováno v:
Journal of visualized experiments : JoVE. (153)
Changes in blood flow velocity and distribution are vital in maintaining tissue and organ perfusion in response to varying cellular needs. Further, appearance of defects in microcirculation can be a primary indicator in the development of multiple pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::303e1f592018d85a3a621cd13bd610f1
https://pubmed.ncbi.nlm.nih.gov/31789313
https://pubmed.ncbi.nlm.nih.gov/31789313
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 10, p e1002155 (2011)
Somitogenesis, the formation of the body's primary segmental structure common to all vertebrate development, requires coordination between biological mechanisms at several scales. Explaining how these mechanisms interact across scales and how events
Externí odkaz:
https://doaj.org/article/014786f8c2ae4847a0fbc120ee84120d
Autor:
James P. Sluka, Zemin Wang, Kenneth W. Dunn, James A. Glazier, Priyom Adhyapok, Xiao Fu, Victoria D. Sluka, Sherry G. Clendenon, James E. Klaunig
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243451 (2020)
PLoS ONE
PLoS ONE
Drug induced liver injury (DILI) and cell death can result from oxidative stress in hepatocytes. An initial pattern of centrilobular damage in the APAP model of DILI is amplified by communication from stressed cells and immune system activation. Whil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::227c665437395e83b2ea3611375ecfc4
https://doi.org/10.1371/journal.pone.0243451
https://doi.org/10.1371/journal.pone.0243451
Autor:
M. Swat, James A. Glazier, Julio M. Belmonte, Sherry G. Clendenon, Robert L. Bacallao, Evan V. Greene, Srividhya Jeyaraman, Guilherme M. Oliveira
Publikováno v:
Molecular Biology of the Cell
Virtual-tissue modeling is used to model emergent cyst growth in polycystic kidney disease. Model predictions, confirmed experimentally, show that decreased cell adhesion is necessary to produce stalk cysts, and loss of contact inhibition causes sacc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d003604e5b96fec52b3364c97f4b3ca
http://europepmc.org/articles/PMC5221598
http://europepmc.org/articles/PMC5221598