Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sherry Carroll"'
Autor:
Sherry Carroll, A. David Rodrigues, Michael Meyer, Kennan C. Marsh, David J. Anderson, Michael W. Decker, Jeffrey E. Campbell
Publikováno v:
CNS Drug Reviews. 6:183-194
ABT-594 [(R)-5-(2-azetedinylmethoxy)-2-chloropyridine mono-tosylate salt] is a neuronal nicotinic acetylcholine receptor (nAChR) agonist with antinociceptive activity in rodent pain models. Whereas the binding affinity of ABT-594 at α4β2-containing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff06af5040eca804000facaea3a840bd
https://doi.org/10.1111/j.1527-3458.2000.tb00146.x
https://doi.org/10.1111/j.1527-3458.2000.tb00146.x
Autor:
Jay S. Trivedi, Stephen P. Arneric, Sherry Carroll, Steven L. Krill, Yihong Qiu, Kennan C. Marsh, Kolette M. Flood
Publikováno v:
International Journal of Pharmaceutics. 157:43-52
ABT-089 is a potent cholinergic channel modulator under investigation for treatment of cognitive disorders. It is a highly water soluble compound with a short elimination half-life of 1.7 h in dogs. Hydrophilic and hydrophobic matrix systems were des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f45c4d194ae80b0f960a4d2acb93bf52
https://doi.org/10.1016/s0378-5173(97)00215-9
https://doi.org/10.1016/s0378-5173(97)00215-9
Autor:
Mark W. Holladay, Kennan C. Marsh, Jay S. Trivedi, Jeffrey E. Campbell, Philip J. Johnson, Ellen M. Roberts, Yihong Qui, James P. Sullivan, Nan-Horng Lin, Bud Peterson, Michael Williams, A. David Rodrigues, Sherry Carroll, Stephen P. Arneric, Jerome F. Daanen
Publikováno v:
Drug Development Research. 41:31-43
ABT-089 [3-(2(S)-pyrrolidinylmethoxy)-2-methylpyridine] is a cholinergic channel modulator (ChCM) that selectively affects the function of neuronal nicotine acetylcholine receptor (nAChR) subtypes, enhances cognitive performance and has neuroprotecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d4530762cfa61e1f92659ee5cc75172
https://doi.org/10.1002/(sici)1098-2299(199705)41:1<31::aid-ddr4>3.0.co
https://doi.org/10.1002/(sici)1098-2299(199705)41:1<31::aid-ddr4>3.0.co
Autor:
J.T. Link, Steven Fung, Marlena Grynfarb, Daisy Deng, Jiahong Wang, Maurice Emery, Annika Goos-Nilsson, Thomas W. von Geldern, Sherry Carroll, Chunqiu Lai, Bryan K. Sorensen
Publikováno v:
Bioorganicmedicinal chemistry letters. 14(16)
The synthesis, activity, metabolic stability, and pharmacokinetics of steroidal and nonsteroidal glucocorticoid receptor modulator–statin hybrids is reported. Potent steroidal antagonist–statin hybrids like 22 (h-GR binding IC 50 =7 nM) and nonst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64067c982b5b39c4e9eb042ebe6b086
https://pubmed.ncbi.nlm.nih.gov/15261265
https://pubmed.ncbi.nlm.nih.gov/15261265
Publikováno v:
Journal of chromatography. B, Biomedical sciences and applications. 695(2)
A high-performance liquid chromatography method for the quantitation of ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine] (I), a new structural type of cholinergic channel modulators (ChCM), is described in this paper using 7-fluoro-4-nitroben
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::788fcaf686b4384b86d78c4fe6ec5057
https://pubmed.ncbi.nlm.nih.gov/9300870
https://pubmed.ncbi.nlm.nih.gov/9300870