Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sherry C Huang"'
Autor:
Heekyung Chung, Dennis J Young, Claudia G Lopez, Thuy-Anh T Le, Jeffrey K Lee, Deena Ream-Robinson, Sherry C Huang, John M Carethers
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3463 (2008)
Microsatellite instability promotes colonic tumorigenesis through generating frameshift mutations at coding microsatellites of tumor suppressor genes, such as TGFBR2 and ACVR2. As a consequence, signaling through these TGFbeta family receptors is abr
Externí odkaz:
https://doaj.org/article/27f6e1c85a4d4529b5e913814679c85f
Autor:
Amber Hildreth, Thomas J. Savides, Sherry C. Huang, Irene Thung, Mark A. Valasek, Sonia Ramamoorthy, Mamata Sivagnanam
Publikováno v:
Case Reports in Genetics, Vol 2018 (2018)
Case Reports in Genetics
Case Reports in Genetics
Constitutional (Biallelic) Mismatch Repair Deficiency is a rare autosomal recessive disorder characterized by numerous cancers presenting as early as the first decade of life. Biallelic germline variants in one of four mismatch repair genes (MLH1, MS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010e36927e433ae130b258608c7dd795
https://doaj.org/article/1ee321ef18f14e52b7ab6ed51d06fbf9
https://doaj.org/article/1ee321ef18f14e52b7ab6ed51d06fbf9
Publikováno v:
Journal of Pediatric Gastroenterology & Nutrition. 58:144-152
Colorectal cancer is a rare disease in the pediatric age group and, when present, suggests an underlying genetic predisposition. The most common hereditary colon cancer susceptibility condition, Lynch syndrome (LS), previously known as hereditary non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::005d501ef007ca543c5a8cf9c2942b80
https://doi.org/10.1097/mpg.0000000000000179
https://doi.org/10.1097/mpg.0000000000000179
Autor:
Noel Weidner, Sherry C. Huang, E. Julieta Smith, Jeffrey Lee, Akihiro Tajima, Ryan T. Doctolero, John M. Carethers, Stayce E. Beck
Publikováno v:
Cancer. 117(3)
BACKGROUND: Patients with hamartomatous polyposis syndromes have increased risk for colorectal cancer (CRC). Although progression of polyps to carcinoma is observed, pathogenic mechanisms remain unknown. The authors examined whether familial hamartom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e9298f8f58fff9c44ed46b73f32bfce
https://pubmed.ncbi.nlm.nih.gov/20845481
https://pubmed.ncbi.nlm.nih.gov/20845481
Autor:
Deborah W. Neklason, Patricia M. Shires, Michelle S. Lewandowski, Michelle W. Done, Randall W. Burt, Sherry C. Huang, Thérèse M. F. Tuohy, Devki S. Saraiya
Familial adenomatous polyposis (FAP (OMIM 175100)) is an autosomal dominant colorectal cancer pre- disposition syndrome characterized by hundreds to thou- sands of colonic polyps and, if untreated by a combination of screening and/or surgical interve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a90d2f37a3378640dab718e15e6143d5
https://europepmc.org/articles/PMC3159508/
https://europepmc.org/articles/PMC3159508/
Autor:
Steven H. Erdman, Sherry C. Huang
Publikováno v:
Current gastroenterology reports. 11(3)
Colon polyps are a common finding in pediatrics and can present with rectal bleeding, abdominal pain, or polyp prolapse from the rectum. Histologically classified as hamartomas, these isolated pediatric polyps lack epithelial dysplasia and have no ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f6390eca27295c660a71d182d811714
https://pubmed.ncbi.nlm.nih.gov/19463221
https://pubmed.ncbi.nlm.nih.gov/19463221
Autor:
Stayce E. Beck, Jayde Kurland, John M. Carethers, Carol J Solomon, Sherry C. Huang, Oscar S. Brann
Publikováno v:
Journal of pediatric gastroenterology and nutrition. 44(3)
Objectives Cyclooxygenase-2 (COX-2) expression is increased in colorectal cancers and has been reported to be upregulated in Peutz-Jeghers polyps. To determine whether germline and somatic loss of BMPR1A in polyps from a patient with juvenile polypos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2996f0024d6893a7512dcb462eec344e
https://pubmed.ncbi.nlm.nih.gov/17325551
https://pubmed.ncbi.nlm.nih.gov/17325551
Autor:
Sherry C. Huang, Jessica Gomez, Stayce E. Beck, Betty L. Cabrera, Barbara H. Jung, Antonio Fiorino, Eunice Del Rosario, Jimmy Y. C. Chow, John M. Carethers
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 291(1)
Bone morphogenetic proteins (BMPs) are members of the transforming growth factor-β superfamily, which utilize BMP receptors and intracellular SMADs to transduce their signals to regulate cell differentiation, proliferation, and apoptosis. Because mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bf975e26295191d617459f6fce08f65
https://pubmed.ncbi.nlm.nih.gov/16769811
https://pubmed.ncbi.nlm.nih.gov/16769811
Autor:
Joel E. Lavine, Sherry C. Huang, Richard D. Kolodner, C. Richard Boland, Patricia S. Boland, Christian N. Arnold, Thu-Thao T. Pham, John M. Carethers, Robert O. Newbury
Publikováno v:
The Journal of pediatrics. 138(5)
Objectives: Hereditary non-polyposis colorectal cancer (HNPCC) is characterized by the early onset of colorectal cancer (~40 years). Adolescent colorectal cancer is unusual in HNPCC families. We speculated that some DNA mismatch repair germline mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b226ef97e1a319de9b2a2a8a7a96d2f6
https://pubmed.ncbi.nlm.nih.gov/11343035
https://pubmed.ncbi.nlm.nih.gov/11343035