Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sherry A. Rovinsky"'
Autor:
Roberta M. Cravo, Carol F. Elias, Lisandra O. Margatho, Sherri Osborne-Lawrence, Jose Donato, Laurent Gautron, Angie L. Bookout, Renata Frazão, Stan D. Atkin, Jeffrey M. Zigman, Charlotte E. Lee, Sherry A. Rovinsky
Publikováno v:
Neuroscience. 173:37-56
Humans and mice with loss-of-function mutations of the genes encoding kisspeptins (Kiss1) or kisspeptin receptor (Kiss1r) are infertile due to hypogonadotropic hypogonadism. Within the hypothalamus, Kiss1 mRNA is expressed in the anteroventral perive
Autor:
Sherri Osborne-Lawrence, Jeffrey M. Zigman, Mario Perello, Michael Lutter, Jakub Woloszyn, Ichiro Sakata, Masashi Yanagisawa, Sherry A. Rovinsky, Shari G. Birnbaum, Jen Chieh Chuang
Publikováno v:
Biological Psychiatry. 67:880-886
Background Ghrelin is a potent orexigenic hormone that likely impacts eating via several mechanisms. Here, we hypothesized that ghrelin can regulate extra homeostatic, hedonic aspects of eating behavior. Methods In the current study, we assessed the
Autor:
Sherri Osborne-Lawrence, Charlotte E. Lee, Ichiro Sakata, Jing Yang, Jeffrey M. Zigman, Joel K. Elmquist, Sherry A. Rovinsky
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 297:E134-E141
Ghrelin is a peptide hormone with many known functions, including orexigenic, blood glucose-regulatory, and antidepressant actions, among others. Mature ghrelin is unique in that it is the only known naturally occurring peptide to be posttranslationa
Autor:
Susan M. Kraemer, Ann Berger, Laurie A. Stargell, W. Scott Moye-Rowley, Sherry A. Rovinsky, David A. Goldstrohm, Susan Hankey
Publikováno v:
Eukaryotic Cell. 5:1081-1090
To characterize the role of the general transcription factor TFIIA in the regulation of gene expression by RNA polymerase II, we examined the transcriptional profiles of TFIIA mutants of Saccharomyces cerevisiae using DNA microarrays. Whole-genome ex
Publikováno v:
Cancer and Metastasis Reviews. 24:251-263
Bone morphogenetic proteins (BMPs) are members of the transforming growth factor-beta (TGF-beta) superfamily serving multiple functions in many cell and tissue types including proliferation, apoptosis, differentiation, chemotaxis, angiogenesis, and m
Publikováno v:
Eukaryotic Cell. 3:318-330
In the yeast Saccharomyces cerevisiae , the transcription factor Yap1p is a central determinant of resistance to oxidative stress. Previous work has demonstrated that Yap1p is recruited from the cytoplasm to the nucleus upon exposure to the oxidants
Autor:
Jeffrey M. Zigman, Joel K. Elmquist, Jen Chieh Chuang, Michael Scott, Mario Perello, Sherri Osborne-Lawrence, Sherry A. Rovinsky, Ichiro Sakata, Charlotte E. Lee
The hormones leptin and ghrelin act in apposition to one another in the regulation of body weight homeostasis. Interestingly, both leptin receptor expression and ghrelin receptor expression have been observed within many of the same nuclei of the cen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c946a9a82ad0254024a4eee877f5eb
https://europepmc.org/articles/PMC3282302/
https://europepmc.org/articles/PMC3282302/
Autor:
Charlotte E. Lee, Sherry A. Rovinsky, Jason G. Anderson, Yoshihide Nakano, Mario Perello, Bradford B. Lowell, Joel K. Elmquist, Ichiro Sakata, Roberto Coppari, Sherri Osborne-Lawrence, Guanghua Xiao, Jeffrey M. Zigman
Publikováno v:
Regulatory peptides. 155(1-3)
Ghrelin is a hormone that influences many physiological processes and behaviors, such as food intake, insulin and growth hormone release, and a coordinated response to chronic stress. However, little is known about the molecular pathways governing gh
Autor:
Joan How, Xiaoming Liu, Chiou-Yan Lai, John F. Engelhardt, George F. Murphy, Sherry A. Rovinsky, Shadi Qasem, Mei-Yu Hsu
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 88(8)
Bone morphogenetic proteins (BMPs) are members of the TGF-beta superfamily responsible for mediating a diverse array of cellular functions both during embryogenesis and in adult life. Previously, we reported that upregulation of BMP7 in human melanom
Oxidant-specific folding of Yap1p regulates both transcriptional activation and nuclear localization
Publikováno v:
The Journal of biological chemistry. 280(49)
The yeast transcriptional regulator Yap1p is a key determinant in oxidative stress resistance. This protein is found in the cytoplasm under non-stressed conditions but rapidly accumulates in the nucleus following oxidant exposure. There it activates