Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Sherry A. Hudson"'
Autor:
Hui Mao, Gen Kano, Sherry A Hudson, Mary Brummet, Nives Zimmermann, Zhou Zhu, Bruce S Bochner
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e68143 (2013)
BackgroundSiglec-F and Siglec-8 are functional paralog proapoptotic cell surface receptors expressed on mouse and human eosinophils, respectively. Whereas Siglec-8 mediated death involves caspases and/or reactive oxygen species (ROS) generation and m
Externí odkaz:
https://doaj.org/article/4b7f42af47e8453a94266e3db410344e
Autor:
Steven J. Ackerman, Sherry A. Hudson, Jian Du, Paul Joseph Cox, Harald Herrmann, El Bdaoui Haddad, Bruce S. Bochner, Barbara Butler, Peter Valent, Paul R. Crocker
Publikováno v:
Journal of Clinical Immunology. 31:1045-1053
The aim of this study is to determine when during hematopoiesis Siglec-8 gets expressed, whether it is expressed on hematologic malignancies, and if there are other non-human species that express Siglec-8.Siglec-8 mRNA and cell surface expression was
Autor:
T.H. Beaty, Ken-ichi Shimizu, Rasika A. Mathias, Sherry A. Hudson, Kathleen C. Barnes, Satoshi Konno, Pei Song Gao, Maria Ilma Araujo, Marc E. Rothenberg, Eduardo Vieira Ponte, Audrey V. Grant, Lin Fu Zhou, Alvaro A. Cruz, Bruce S. Bochner, Nives Zimmermann, Song Nan Su, Nicholas Rafaels, Masaharu Nishimura, Nobuyuki Hizawa
Publikováno v:
European Journal of Human Genetics. 18:713-719
Sialic acid-binding immunoglobulin-like lectin-8 (Siglec-8) promotes the apoptosis of eosinophils and inhibits FcvarepsilonRI-dependent mediator release from mast cells. We investigated the genetic association between sequence variants in Siglec-8 an
Autor:
Sherry A. Hudson, Leonardo Nimrichter, Wouter Laroy, Ronald L. Schnaar, Bruce S. Bochner, Konstantinos Konstantopoulos, Robert J. Cotter, Michael Tiemeyer, Monica M. Burdick, Kazuhiro Aoki, Mark A. Fierro, Christopher E. Von Seggern
Publikováno v:
Blood. 112:3744-3752
Selectins on activated vascular endothelium mediate inflammation by binding to complementary carbohydrates on circulating neutrophils. The human neutrophil receptor for E-selectin has not been established. We report here that sialylated glycosphingol
Autor:
Bruce S. Bochner, Nives Zimmermann, Sherry A. Hudson, Y. Yamada, Marc E. Rothenberg, M. L. McBride, K. D. Cromie, Paul R. Crocker, Claire Jones
Publikováno v:
Allergy. 63:1156-1163
Eosinophils are leukocytes (1) that are primarily tissue-dwelling cells found constitutively in several organs such as the gastrointestinal tract (2, 3). However, in inflammatory conditions, eosinophils accumulate in large numbers in other tissues, s
Autor:
Konstantinos Konstantopoulos, Monica M. Burdick, Sherry A. Hudson, Fatimah Bte Mustafa, Lina H. K. Lim, Bruce S. Bochner
Publikováno v:
The Journal of Immunology. 176:5346-5353
Basophils have been shown to accumulate in allergic airways and other extravascular sites. Mechanisms responsible for the selective recruitment of basophils from the blood into tissue sites remain poorly characterized. In this study, we characterized
Publikováno v:
Clinical Experimental Allergy Reviews. 4:76-81
Summary Eosinophil recruitment and activation are regarded as central to the pathophysiology of allergic diseases, including asthma. An improved understanding of the mechanisms involved in these responses is therefore of great relevance to asthma pat
Publikováno v:
Journal of Allergy and Clinical Immunology. 112:930-934
Background Segmental antigen bronchoprovocation has long been used as a model to study allergic pulmonary inflammatory responses. Among the characteristics of the resulting cellular infiltrate is the preferential recruitment of T H 2 lymphocytes. The
Publikováno v:
Blood. 101:5014-5020
Sialic acid binding immunoglobulin-like lectin 8 (Siglec-8), which exists in 2 isoforms including one possessing cytoplasmic tyrosine motifs, is expressed only on human eosinophils, basophils, and mast cells. Until now, its function was unknown. Here
Publikováno v:
Cell Communication & Adhesion. 10:119-128
We examined the effect of the protein kinase C activator phorbol-12-myristate-13-acetate (PMA) on the human eosinophil adhesion molecule phenotype and attachment to VCAM-1 via alpha4 and alphad integrins under static and flow conditions. PMA increase