Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Sherry, Leonard"'
Autor:
Sherry Leonard, Roberta Benfante
Publikováno v:
Pharmacological Research, Vol 192, Iss , Pp 106783- (2023)
The α7 nicotinic receptor (α7 nAChR) is an important entry point for Ca2+ into the cell, which has broad and important effects on gene expression and function. The gene (CHRNA7), mapping to chromosome (15q14), has been genetically linked to a large
Externí odkaz:
https://doaj.org/article/0e3287b64a5044e7ab9e0826b598e3bf
Autor:
Bell, James Washington, Woodworth, Robert T., Clague, Ewan, Robinson, Mary Electa, Levine, Louis, Wallis, Allen, Wassen, D. E., Robertson, Jack, Boddy, F. M., Allen, H. K., Keezer, Dexter M., Gainsbrugh, Martin, Arthur, Henry, Schmidt, Emerson P., Hadley, W. E., Vaughn, Jack, Sherry, Leonard, Petshek, Kirk, Levine, Louis, Taylor, Ancel N., Schultz, T. W., Blough, Roy, Phillips, W. T., Hoadley,, W. E., Corson, Louis D., Gitlow, A. L., Wellemayer, J. Fletcher, Kaplan, A. D. H., Higgins, Benjamin, Somers, Gerald, Harris, Seymour
Publikováno v:
The American Economic Review, 1959 May 01. 49(2), 581-593.
Externí odkaz:
https://www.jstor.org/stable/1816149
Autor:
Mark L. Dell'Acqua, Sharon L. Graw, Karen E. Stevens, Sherry Leonard, Kevin S. Choo, Ronald K. Freund
Publikováno v:
Neuroscience Letters. 627:1-6
Reduced α7 nicotinic acetylcholine receptor (nAChR) function is linked to impaired hippocampal-dependent sensory processing and learning and memory in schizophrenia. While knockout of the Chrna7 gene encoding the α7nAChR on a C57/Bl6 background res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a886a01a201c195bdd449d4564df37
https://doi.org/10.1016/j.neulet.2016.05.043
https://doi.org/10.1016/j.neulet.2016.05.043
Autor:
Sharon K. Hunter, Betsey M. Chambers, Sherry Leonard, Amanda J. Law, Randal G. Ross, Robert Freedman, M. Camille Hoffman, Lizbeth McCarthy, Gary O. Zerbe
Publikováno v:
American Journal of Psychiatry. 173:509-516
Objective:α7-Nicotinic receptors are involved in the final maturation of GABA inhibitory synapses before birth. Choline at levels found in the amniotic fluid is an agonist at α7-nicotinic receptors. The authors conducted a double-blind placebo-cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa95b70abb15bc76109d296cb3c0d8ce
https://doi.org/10.1176/appi.ajp.2015.15091188
https://doi.org/10.1176/appi.ajp.2015.15091188
Autor:
Robert Freedman, Melissa L. Sinkus, Sherry Leonard, Sharon L. Graw, Henry A. Lester, Randal G. Ross
Publikováno v:
Neuropharmacology. 96:274-288
The human α7 neuronal nicotinic acetylcholine receptor gene (CHRNA7) is ubiquitously expressed in both the central nervous system and in the periphery. CHRNA7 is genetically linked to multiple disorders with cognitive deficits, including schizophren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1c0097f91ddc9845e9a7f8d1c77f14f
https://doi.org/10.1016/j.neuropharm.2015.02.006
https://doi.org/10.1016/j.neuropharm.2015.02.006
Autor:
Kalynn M. Schulz, Kayla F. Brooks, Chakeer Drake-Frazier, Megan E. Zajkowski, Mary E. Gasparrini, Sherry Leonard, Catherine E. Adams, Alison D. Kreisler, Karen E. Stevens, Jennifer N. Pearson
Publikováno v:
Behavioural Brain Research. 268:104-110
Brain cholinergic dysfunction is associated with neuropsychiatric illnesses such as depression, anxiety, and schizophrenia. Maternal stress exposure is associated with these same illnesses in adult offspring, yet the relationship between prenatal str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8763f153e03cac2de36ed8bce8b76376
https://doi.org/10.1016/j.bbr.2014.03.031
https://doi.org/10.1016/j.bbr.2014.03.031
Publikováno v:
Schizophrenia Research. 150:386-391
Background Schizophrenia is associated with altered tyrosine transport across plasma membranes. This is typically demonstrated by measuring the uptake of radiolabeled tyrosine in cultured human fibroblasts. Our primary goal was to determine whether t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d6702f0ed24bfd1d2a2b3a262df472
https://doi.org/10.1016/j.schres.2013.08.041
https://doi.org/10.1016/j.schres.2013.08.041
Publikováno v:
Brain, Behavior, and Immunity. 32:51-62
Schizophrenia is a common mental illness with a large genetic component. Three genome-wide association studies have implicated the major histocompatibility complex gene region on chromosome 6p21.3-22.1 in schizophrenia. In addition, nicotine, which i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b93e8e1a82d611e2043dd2fc627fa4d
https://doi.org/10.1016/j.bbi.2013.01.087
https://doi.org/10.1016/j.bbi.2013.01.087
Autor:
Ann Olincy, Tasha E. Fingerlin, Alexis Franks, Sarah H. Stephens, Sherry Leonard, Brandie D. Wagner, Judith Logel, Milda Palionyte, Robert Freedman, Randal G. Ross, Ralph Berger
Publikováno v:
Psychiatric Genetics. 22:1-14
OBJECTIVE The chromosomal region, 15q13-q14, including the α7 nicotinic acetylcholine receptor gene, CHRNA7, is a replicated region for schizophrenia. This study fine-mapped genes at 15q13-q14 to determine whether the association is unique to CHRNA7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b018ba677a8624de7c59ce8bdea1869
https://doi.org/10.1097/ypg.0b013e32834c0c33
https://doi.org/10.1097/ypg.0b013e32834c0c33