Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sherry, Boozer"'
Autor:
Sherry Boozer, Jianmin Wang, John J. Harrington, Rob Perry, Stephen Rundlett, Nancy S Wang, Anthony E. Ting, Youssef L. Bennani, Kurt R. Brunden, Joel Danzig, James T. Anderson, Amy Raber, Steven M. Murphy, Tom Dent
Publikováno v:
Journal of Medicinal Chemistry. 48:2756-2758
Analogues of the natural product noscapine were synthesized, and their potential as antitumor agents were examined. The discovery of a novel regio- and stereoselective O-demethylation led to the synthesis of several O-alkylated analogues that induced
Autor:
Sherry, Boozer, Nicholas, Lehman, Uma, Lakshmipathy, Brad, Love, Amy, Raber, Anirban, Maitra, Robert, Deans, Mahendra S, Rao, Anthony E, Ting
Publikováno v:
Journal of stem cells. 4(1)
The therapeutic benefits of adult adherent stem cells are currently being investigated in clinical trials for a variety of diseases. Data from initial clinical studies are promising and as a consequence of moving to later stage clinical studies, have
Autor:
Ge Zhang, Joseph Lee, Cory Swingen, Xiaohong Wang, Jianyi Zhang, Catherine M. Verfaillie, Qingsong Hu, Abdul Mansoor, Sherry Boozer, Robert J. Bache, Lepeng Zeng, Piradeep Suntharalingam, Abner M. Mhashilkar, Arthur H. L. From, Julia Feygin, Robert J. Deans, Carmelo J. Panetta
Publikováno v:
Circulation. 115(14)
Background— The present study examined whether transplantation of adherent bone marrow–derived stem cells, termed pMultistem, induces neovascularization and cardiomyocyte regeneration that stabilizes bioenergetic and contractile function in the i
Autor:
Jianmin Wang, Laurel Faga, Joel Danzig, John J. Harrington, James T. Anderson, Anthony E. Ting, Alain Stricker-Krongrad, Kurt R. Brunden, William F. Hodnick, Youssef L. Bennani, Sherry Boozer, Robert Perry, Chris Crumrine, Stephen Rundlett, Gary Pawlowski, Amy Raber, Steven M. Murphy, Tom Dent
Publikováno v:
Journal of medicinal chemistry. 48(23)
Analogues of the natural product noscapine were synthesized and their potential as antitumor agents evaluated. The discovery of a novel regioselective O-demethylation facilitated the synthesis of the potent aniline 6, which arrests mammalian cells in
Autor:
Steven M. Murphy, Bruce Sherf, Tom Dent, Daniel P. Silver, Andrew Bailey, L. Nathan Tumey, Jianmin Wang, Youssef L. Bennani, Elizabeth Ann Gleason, David C. Bom, Bayard Huck, Christina Leventhal, Sherry Boozer, John J. Harrington, Stephen Rundlett, Kurt R. Brunden
Publikováno v:
Bioorganicmedicinal chemistry letters. 15(2)
Flap endonuclease-1 (FEN1) is a key enzyme involved in base excision repair (BER), a primary pathway utilized by mammalian cells to repair DNA damage. Sensitization to DNA damaging agents is a potential method for the improvement of the therapeutic w
Autor:
Jianmin Wang, John J. Harrington, Daniel P. Silver, Bayard Huck, Kurt R. Brunden, Christina Leventhal, Bruce Sherf, L. Nathan Tumey, Tom Dent, Steven M. Murphy, Elizabeth Ann Gleason, Andrew Bailey, Sherry Boozer, Stephen Rundlett, Youssef L. Bennani
Publikováno v:
Bioorganicmedicinal chemistry letters. 14(19)
There have been several recent reports of chemopotentiation via inhibition of DNA repair processes. Flap endonuclease 1 (FEN1) is a key enzyme involved in base excision repair (BER), a primary pathway utilized by mammalian cells to repair DNA damage.
Autor:
Kalok Lo, Neil Veloso, Kevin Cothren, Rakesh Ramachandran, Matthew D. Ducar, Laura Lerner, John J. Harrington, Emery Smith, Robert W. Mays, Joel Danzig, Dana Costanzo, Scott Cain, Christina Leventhal, P. David Jackson, Sherry Boozer, Jennifer Hess, Mark Thornton, Stephen Rundlett, Karen McElligott, Bruce Sherf, Rob Perry, Jessica Whittington, Jason Offenbacher, Alison K. Klika
Publikováno v:
Nature biotechnology. 19(5)
Here we report the use of random activation of gene expression (RAGE) to create genome-wide protein expression libraries. RAGE libraries containing only 5 x 10(6) individual clones were found to express every gene tested, including genes that are nor
Autor:
Piratheepan Suntharalingam, Sherry Boozer, Stephen Rundlett, Catherine M. Verfaillie, Robert J. Deans
Publikováno v:
Blood. 104:4261-4261
Summary The clinical utility of an ex-vivo expanded stem cell population is dependent on both safety and efficacy. As an initial step toward ensuring that expanded adult stem cell populations are safe, we harvested bone marrows from four different st
Autor:
Mikhail Konoplyannikov, Sherry Boozer, Manfred Boehm, Robert J. Lederman, Leilani E. Beltran, Anthony Mathur, Hong San, Jason C. Kovacic, Andrew Wragg, Robert J. Deans, Jason A. Mellad
Publikováno v:
Journal of Molecular Medicine. 86(11):1221-1232
Recruitment and retention of circulating progenitor cells at the site of injured or ischemic tissues facilitates adult neo-vascularization. We hypothesized that cell therapy could modulate local neo-vascularization through the vascular endothelial gr