Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sherrie Secunda"'
Publikováno v:
Pharmacology. 46:91-100
A series of 55 2-alkyloxy-, 2-aryloxy- and 2-aralkyloxy-adenosines was screened as inhibitors of the binding of [3H] R -phenyl-isopropyladenosine to A1 adenosine
Autor:
Charles Nishihira, Thomas F. Spande, Anthony. Wisnieski, John W. Daly, Sherrie Secunda, H. Martin Garraffo, John F. Cover
Publikováno v:
Toxicon. 30:887-898
Dendrobatid frogs produce a diverse set of alkaloids, whose profiles appear characteristic of frogs of each species or, in the case of variable species, of each population. In the case of one widespread species, Dendrobates auratus, alkaloid profiles
Autor:
Anthony. Wisnieski, Sherrie Secunda, John W. Daly, John F. Cover, Thomas F. Spande, H. M. Garraffo
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 32(6)
The skin of poison frogs (Dendrobatidae) contains a wide variety of alkaloids that presumably serve a defensive role. These alkaloids persist for years in captivity, but are not present in captiveraised frogs. Alkaloids fed to poison frogs (Dendrobat
Publikováno v:
Journal of medicinal chemistry. 34(9)
N6-Substituted 9-methyladenines are potent antagonists of the activation of A1 adenosine receptors. The present study assessed the effect of N6 and N-9 substituents on the binding of adenines to the A1 and A2 receptors, respectively, of rat brain cor
Autor:
William L. Padgett, Ray A. Olsson, Sherrie Secunda, John W. Daly, Masayuki Ueeda, Robert D. Thompson
Publikováno v:
Life sciences. 49(18)
This study compared the structure-activity relationships of 16 analogues at the A1 and A2 adenosine receptors (A1AR, A2AR) of rat and guinea pig. Radioligand binding studies revealed no marked differences in the affinities of each analogue at the A1A
Autor:
Cyrus R. Creveling, Daniel P. Rossignol, Sherrie Secunda, John W. Daly, Matthew J. Sharp, Yukio Nishizawa, E. T. McNeal, Maureen Bell, Fabian Gusovsky, Larry E. Overman
Publikováno v:
Biochemical pharmacology. 40(2)
Pumiliotoxin B (PTX-B) and a variety of congeneric alkaloids and synthetic analogs stimulated sodium flux and phosphoinositide breakdown in guinea pig cerebral cortical synaptoneurosomes. The effects of PTX-B and active congeners and analogs on sodiu
Sulfur-Containing 1,3-Dialkylxanthine Derivatives as Selective Antagonists at A1-Adenosine Receptors
Autor:
Kenneth A. Jacobson, Udai Kammula, Barton James Bradbury, John L. Neumeyer, Jean Michel Campagne, Wolfgang Pfleiderer, Leonidas Kiriasis, Sherrie Secunda, Suzanne Barone, John W. Daly
Sulfur-containing analogues of 8-substituted xanthines were prepared in an effort to increase selectivity or potency as antagonists at adenosine receptors. Either cyclopentyl or various aryl substituents were utilized at the 8-position, because of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f911e9c715e2f39bed6c2ea50509006b
https://europepmc.org/articles/PMC3479653/
https://europepmc.org/articles/PMC3479653/
Publikováno v:
Brain research. 492(1-2)
The effects of pyrethroids were studied on phosphoinositide breakdown in guinea pig synaptoneurosomes. Similar to other agents that activate voltage-dependent sodium channels, type I and type II pyrethroids stimulated phosphoinositide breakdown. Type