Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sherrie Jean"'
Autor:
Veronica Obregon-Perko, Katherine M. Bricker, Gloria Mensah, Ferzan Uddin, Laura Rotolo, Daryll Vanover, Yesha Desai, Philip J. Santangelo, Sherrie Jean, Jennifer S. Wood, Fawn C. Connor-Stroud, Stephanie Ehnert, Stella J. Berendam, Shan Liang, Thomas H. Vanderford, Katharine J. Bar, George M. Shaw, Guido Silvestri, Amit Kumar, Genevieve G. Fouda, Sallie R. Permar, Ann Chahroudi
Publikováno v:
JCI Insight, Vol 6, Iss 23 (2021)
Understanding viral rebound in pediatric HIV-1 infection may inform the development of alternatives to lifelong antiretroviral therapy (ART) to achieve viral remission. We thus investigated viral rebound after analytical treatment interruption (ATI)
Externí odkaz:
https://doaj.org/article/983674d7bb4541aa9e530e783bfd9106
Autor:
Katherine M. Bricker, Veronica Obregon-Perko, Brianna Williams, Danielle Oliver, Ferzan Uddin, Margaret Neja, Louis Hopkins, Amir Dashti, Sherrie Jean, Jennifer S. Wood, Stephanie Ehnert, Shan Liang, Thomas Vanderford, Gregory K. Tharp, Steven E. Bosinger, Amanda P. Schauer, Maud Mavigner, Mackenzie L. Cottrell, David Margolis, Richard M. Dunham, Ann Chahroudi
Publikováno v:
Journal of virology. 96(7)
The "shock and kill" strategy for HIV-1 cure incorporates latency-reversing agents (LRA) in combination with interventions that aid the host immune system in clearing virally reactivated cells. LRAs have not yet been investigated in pediatric clinica
Autor:
Jenna Read, Colin T. King, Maria Pino, Mirko Paiardini, Heather Amrine-Madsen, Michael Nekorchuk, Chi Ngai Chan, Cristin M. Galardi, Hong Wang, James Schawalder, Katharine J. Bar, A. Alicia Koblansky, Colleen S. McGary, Kevin Nguyen, Jacob D. Estes, Sherrie Jean, Samuel L. M. Raines, Shane D. Falcinelli, Jeffrey D. Lifson, Shari Gordon, Luca Micci, Guido Silvestri, Andrew Sanderson, Justin L. Harper, Brian Johns, David Favre, Emily Lindemuth, Kathleen Busman-Sahay, Barbara Cervasi, David M. Margolis
Publikováno v:
Nature Medicine. 26:519-528
The primary human immunodeficiency virus (HIV) reservoir is composed of resting memory CD4+ T cells, which often express the immune checkpoint receptors programmed cell death protein 1 (PD-1) and cytotoxic T lymphocyte-associated protein 4 (CTLA-4),
Autor:
Genevieve G. Fouda, George M. Shaw, Amit Kumar, Veronica Obregon-Perko, Guido Silvestri, Stephanie Ehnert, Ferzan Uddin, Ann Chahroudi, Yesha Desai, Jennifer S. Wood, Daryll Vanover, Sallie R. Permar, Katherine M. Bricker, Shan Liang, Sherrie Jean, Laura Rotolo, Katharine J. Bar, Stella J. Berendam, Philip J. Santangelo, Gloria Mensah, Fawn C Connor-Stroud, Thomas H. Vanderford
Publikováno v:
JCI Insight
Understanding viral rebound in pediatric HIV-1 infection may inform the development of alternatives to lifelong antiretroviral therapy (ART) to achieve viral remission. We thus investigated viral rebound after analytical treatment interruption (ATI)
Autor:
Guido Ferrari, Neeta Shenvi, Thomas H. Vanderford, Susan Pereira Ribeiro, Wen-Hsiang Chen, David C. Montefiori, Talha Abid, Alessandro Sette, Daniela Weiskopf, Debashis Dutta, Katharine Floyd, Shelly Wang, Dieter Mielke, Sudhir Pai Kasturi, Georgia D. Tomaras, Pamela A. Kozlowski, Celia C. LaBranche, Maria Pino, Jungsoon Lee, Sherrie Jean, Venkata Viswanadh Edara, Xiaoying Shen, Justin Pollara, Justin C Smith, Mirko Paiardini, Rafick Pierre Sekaly, Fawn Connor-Stroud, Joyce Cohen, Gabriela Pacheco-Sanchez, Hongmei Gao, Zhuyun Liu, Christopher B. Fox, Sanjeev Gumber, Junfei Wei, Nathan Eisel, Maria Elena Bottazzi, Rachelle L. Stammen, Jennifer S. Wood, Shannon Kirejczyk, Bin Zhan, Muhammad Bilal Latif, Peter J. Hotez, Kirk Easley, Ulrich Strych, Jeroen Pollet, Mehul S. Suthar, Mark A. Tomai
Publikováno v:
Science immunology. 6(61)
Ongoing SARS-CoV-2 vaccine development is focused on identifying stable, cost-effective, and accessible candidates for global use, specifically in low and middle-income countries. Here, we report the efficacy of a rapidly scalable, novel yeast expres
Autor:
Shelly Wang, Steven E. Bosinger, Joyce Cohen, Sally Shin, Pei Yong Shi, Stephanie Fischinger, Fawn Connor-Stroud, Amit A. Upadhyay, Sailaja Gangadhara, Katharine Floyd, Sanjeev Gumber, Narayanaiah Cheedarla, Jennifer S. Wood, Mehul S. Suthar, Rama Rao Amara, Anusmita Sahoo, Ayalnesh Shiferaw, Nanda Kishore Routhu, Rachelle L. Stammen, Venkata Viswanadh Edara, David C. Montefiori, Vineet D. Menachery, Venkata S. Bollimpelli, Shannon Kirejczyk, Caroline Atyeo, Galit Alter, Thomas H. Vanderford, Lilin Lai, Sherrie Jean, Sheikh Abdul Rahman, Kathryn L. Pellegrini, Arun K. Boddapati
Publikováno v:
Immunity
A combination of vaccination approaches will likely be necessary to fully control the SARS-CoV-2 pandemic. Here, we show that modified vaccinia Ankara (MVA) vectors expressing membrane anchored pre-fusion stabilized spike (MVA/S), but not secreted S1
Autor:
Amit A. Upadhyay, Sudhir Pai Kasturi, Elise G. Viox, Steven E. Bosinger, Ernestine A. Mahar, Michael N. Sayegh, Sanjeev Gumber, Justin L. Harper, Arun K. Boddapati, Sijia Tao, Shelly Wang, Rebecca D. Levit, Thomas H. Vanderford, Michelle Y.H. Lee, Shannon Kirejczyk, Sherrie Jean, Keivan Zandi, Susan Pereira Ribeiro, Carly E. Starke, Lanfang Wang, Daniela Weiskopf, Maria Pino, Joyce Cohen, Timothy N. Hoang, Tristan R. Horton, Gregory K. Tharp, Jesse J. Waggoner, Kathleen Busman-Sahay, Anne Piantadosi, Olivia M. Delmas, Kathryn L. Pellegrini, Jennifer S. Wood, Jacob D. Estes, Peter D. Filev, Mirko Paiardini, Rachelle L. Stammen, Elizabeth N. Beagle, Zachary Strongin, Raymond F. Schinazi, Rafick Pierre Sekaly, Kimberly A. Cooney, Fawn Connor-Stroud, Hilmi Al Shakhshir
Publikováno v:
bioRxiv
Effective therapeutics aimed at mitigating COVID-19 symptoms are urgently needed. SARS-CoV-2 induced hypercytokinemia and systemic inflammation are associated with disease severity. Baricitinib, a clinically approved JAK1/2 inhibitor with potent anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6f3ad475da4ad3af4b09b02cb47beb
https://doi.org/10.1101/2020.09.16.300277
https://doi.org/10.1101/2020.09.16.300277
Autor:
Zachary Strongin, Timothy N. Hoang, Rebecca D. Levit, Shelly Wang, Sherrie Jean, Kimberly A. Cooney, Susan Pereira Ribeiro, Mirko Paiardini, Lanfang Wang, Gregory K. Tharp, Rafick Pierre Sekaly, Michael Nekorchuk, Elise G. Viox, Raymond F. Schinazi, Justin L. Harper, Jacob D. Estes, Steven E. Bosinger, Michelle Y.H. Lee, Hilmi Al-Shakhshir, Rachelle L. Stammen, Kathleen Busman-Sahay, Arun K. Boddapati, Daniela Weiskopf, Sijia Tao, Anne Piantadosi, Guido Silvestri, Kathryn L. Pellegrini, Maria Pino, Michael N. Sayegh, Fawn Connor-Stroud, Thomas H. Vanderford, Tristan R. Horton, Jesse J. Waggoner, Joyce Cohen, Olivia M. Delmas, Jennifer S. Wood, Peter D. Filev, Carly E. Starke, Amit A. Upadhyay, Sudhir Pai Kasturi, Ernestine A. Mahar, Shannon Kirejczyk, Elizabeth N. Beagle, Sanjeev Gumber, Keivan Zandi
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
Cell
article-version (status) pre
article-version (number) 1
Cell
SARS-CoV-2 induced hypercytokinemia and inflammation are critically associated with COVID-19 disease severity. Baricitinib, a clinically approved JAK1/2 inhibitor, is currently being investigated in COVID-19 clinical trials. Here, we investigated the
Autor:
Damien A. Fair, Ann Chahroudi, Martin Styner, Jakob Habib, Maria C. Alvarado, Eric Earl, Joyce Cohen, Carmen Mattingly, Eric Feczko, Mark W. Burke, Mar M. Sanchez, Mehul S. Suthar, Zsofia Kovacs-Balint, Sherrie Jean, Maud Mavigner, Sanjeev Gumber, Jessica Raper
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Zika virus (ZIKV) infection has a profound impact on the fetal nervous system. The postnatal period is also a time of rapid brain growth, and it is important to understand the potential neurobehavioral consequences of ZIKV infection during infancy. H
Autor:
Steven E. Bosinger, Gavin C. Sampey, Zhang Wang, Jean-Pierre Routy, Robert G. Ferris, Rae Ann Spagnuolo, Edward P. Browne, Brandon F. Keele, Greg K. Tharp, Christopher C. Nixon, Nils Schoof, Christine M. Fennessey, Chandrav De, Corinne G. Cammon, Rachel A. Cleary, David Favre, Nancie M. Archin, J. Victor Garcia, Jennifer Deutsch, Angela Wahl, Sean Maguire, Hasse Walum, Thomas H. Vanderford, Cameron Mattingly, David M. Margolis, Baolin Liao, Nathaniel J. Schramm, Richard M. Dunham, Amit A. Upadhyay, Jessica H. Brehm, Cristin M. Galardi, Saintedym Wills, Corbin D. Jones, Maud Mavigner, Sherrie Jean, Jeffrey D. Lifson, Matt Kanke, Guido Silvestri, Phong T. Ho, Alyssa D. Brooks, Ann Chahroudi, David M. Irlbeck, Shane D. Falcinelli
Publikováno v:
Nature
Long-lasting, latently infected resting CD4+ T cells are the greatest obstacle to obtaining a cure for HIV infection, as these cells can persist despite decades of treatment with antiretroviral therapy (ART). Estimates indicate that more than 70 year