Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sherrie Damare"'
Autor:
Mark N. Stein, Jyoti Malhotra, Rohinton S. Tarapore, Usha Malhotra, Ann W. Silk, Nancy Chan, Lorna Rodriguez, Joseph Aisner, Robert D. Aiken, Tina Mayer, Bruce G. Haffty, Jenna H. Newman, Salvatore M. Aspromonte, Praveen K. Bommareddy, Ricardo Estupinian, Charles B. Chesson, Evita T. Sadimin, Shengguo Li, Daniel J. Medina, Tracie Saunders, Melissa Frankel, Aparna Kareddula, Sherrie Damare, Elayne Wesolowsky, Christian Gabel, Wafik S. El-Deiry, Varun V. Prabhu, Joshua E. Allen, Martin Stogniew, Wolfgang Oster, Joseph R. Bertino, Steven K. Libutti, Janice M. Mehnert, Andrew Zloza
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-9 (2019)
Abstract Background ONC201 is a small molecule antagonist of DRD2, a G protein-coupled receptor overexpressed in several malignancies, that has prolonged antitumor efficacy and immunomodulatory properties in preclinical models. The first-in-human tri
Externí odkaz:
https://doaj.org/article/cc2e3e6b70b34104941a2588a1bfa557
Autor:
Praveen K. Bommareddy, Wafik S. El-Deiry, Tracie Saunders, Salvatore M. Aspromonte, Lorna Rodriguez, Rohinton Tarapore, Janice M. Mehnert, Steven K. Libutti, Nancy Chan, Ann W. Silk, Jenna H. Newman, Charles B. Chesson, Elayne Wesolowsky, Daniel J. Medina, Christian Gabel, Martin Stogniew, Shengguo Li, Joseph R. Bertino, Joshua E. Allen, Mark N. Stein, Evita Sadimin, Aparna Kareddula, Joseph Aisner, Sherrie Damare, Jyoti Malhotra, Wolfgang Oster, Varun V. Prabhu, Bruce G. Haffty, Andrew Zloza, Ricardo Estupinian, Tina M. Mayer, Melissa Frankel, Robert Aiken, Usha Malhotra
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-9 (2019)
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-9 (2019)
Background ONC201 is a small molecule antagonist of DRD2, a G protein-coupled receptor overexpressed in several malignancies, that has prolonged antitumor efficacy and immunomodulatory properties in preclinical models. The first-in-human trial of ONC