Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sherri B. Briggs"'
Autor:
Madalyn Hafenbreidel, Sherri B. Briggs, Meghana Arza, Shalakha Bonthu, Cadence Fisher, Annika Tiller, Alice B. Hall, Shayna Reed, Natasha Mayorga, Li Lin, Susan Khan, Michael D. Cameron, Gavin Rumbaugh, Courtney A. Miller
Publikováno v:
bioRxiv
Inhibiting the actin motor ATPase nonmuscle myosin II (NMII) with blebbistatin (Blebb) in the basolateral amgydala (BLA) depolymerizes actin, resulting in an immediate, retrieval-independent disruption of methamphetamine (METH)-associated memory. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffeb6cb1607e007ee16afb0013ec6c45
https://europepmc.org/articles/PMC10245849/
https://europepmc.org/articles/PMC10245849/
Publikováno v:
Learning & Memory. 28:187-194
Research into the neural mechanisms that underlie higher-order cognitive control of eating behavior suggests that ventral hippocampal (vHC) neurons, which are critical for emotional memory, also inhibit energy intake. We showed previously that optoge
Nonmuscle myosin II inhibition disrupts methamphetamine-associated memory in females and adolescents
Publikováno v:
Neurobiology of Learning and Memory. 139:109-116
Memories associated with drug use can trigger strong motivation for the drug, which increases relapse vulnerability in substance use disorder (SUD). Currently there are no treatments for relapse to abuse of psychostimulants, such as methamphetamine (
Publikováno v:
Learning & Memory. 24:70-75
Depolymerizing actin in the amygdala through nonmuscle myosin II inhibition (NMIIi) produces a selective, lasting, and retrieval-independent disruption of the storage of methamphetamine-associated memories. Here we report a similar disruption of memo
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 357:56-65
This study investigated the functional role of cyclin-dependent kinase inhibitor 1a (Cdkn1a or p21) in cocaine-induced responses using a knockout mouse model. Acute locomotor activity after cocaine administration (15 mg/kg, i.p.) was decreased in p21
Publikováno v:
Learningmemory (Cold Spring Harbor, N.Y.). 25(9)
Using pharmacologic and genetic approaches targeting actin or the actin-driving molecular motor, nonmuscle myosin II (NMII), we previously discovered an immediate, retrieval-independent, and long-lasting disruption of methamphetamine- (METH-) and amp
Publikováno v:
Addiction Biology. 22:446-456
Allowing rats extended access to cocaine self-administration is thought to recapitulate several key aspects of cocaine addiction in humans. Understanding the mechanisms that underlie drug-induced neuroadaptations that persist in the brain after protr
Autor:
Courtney A. Miller, Erica J. Young, Li Lin, Stephanie E. Sillivan, Gavin Rumbaugh, Michael D. Cameron, Sherri B. Briggs, Ashley M. Blouin
Publikováno v:
Molecular Psychiatry. 21:615-623
Memories associated with drug use increase vulnerability to relapse in substance use disorder (SUD) and there are no pharmacotherapies for the prevention of relapse. Previously, we reported a promising finding that storage of memories associated with
Publikováno v:
CNS & Neurological Disorders - Drug Targets. 14:731-737
A high rate of relapse is a defining characteristic of substance use disorder for which few treatments are available. Exposure to environmental cues associated with previous drug use can elicit relapse by causing the involuntary retrieval of deeply e
Publikováno v:
Addiction biology. 22(2)
Allowing rats extended access to cocaine self-administration is thought to recapitulate several key aspects of cocaine addiction in humans. Understanding the mechanisms that underlie drug-induced neuroadaptations that persist in the brain after protr