Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Sherri A, McFarland"'
Autor:
Abul Kalam Azad, Lothar Lilge, Nawaid H. Usmani, John D. Lewis, Houston D. Cole, Colin G. Cameron, Sherri A. McFarland, Deepak Dinakaran, Ronald B. Moore
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Traditional external light-based Photodynamic Therapy (PDT)’s application is limited to the surface and minimal thickness tumors because of the inefficiency of light in penetrating deep-seated tumors. To address this, the emerging field of radiatio
Externí odkaz:
https://doaj.org/article/89781f0f63ab417a95092c6c120eee6e
Autor:
Girgis Obaid, Shazia Bano, Hanna Thomsen, Susan Callaghan, Nimit Shah, Joseph W. R. Swain, Wendong Jin, Xiadong Ding, Colin G. Cameron, Sherri A. McFarland, Juwell Wu, Mark Vangel, Svetla Stoilova‐McPhie, Jie Zhao, Mari Mino‐Kenudson, Charles Lin, Tayyaba Hasan
Publikováno v:
Advanced Science, Vol 9, Iss 24, Pp n/a-n/a (2022)
Abstract Desmoplasia is characteristic of pancreatic ductal adenocarcinoma (PDAC), which exhibits 5‐year survival rates of 3%. Desmoplasia presents physical and biochemical barriers that contribute to treatment resistance, yet depleting the stroma
Externí odkaz:
https://doaj.org/article/0670866fd506442c8ba84eb912ca8dbe
Autor:
Olaitan E. Oladipupo, Meredith C. Prescott, Emily R. Blevins, Jessica L. Gray, Colin G. Cameron, Fengrui Qu, Nicholas A. Ward, Abigail L. Pierce, Elizabeth R. Collinson, James Fletcher Hall, Seungjo Park, Yonghyun Kim, Sherri A. McFarland, Igor Fedin, Elizabeth T. Papish
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5980 (2023)
Protic ruthenium complexes using the dihydroxybipyridine (dhbp) ligand combined with a spectator ligand (N,N = bpy, phen, dop, Bphen) have been studied for their potential activity vs. cancer cells and their photophysical luminescent properties. Thes
Externí odkaz:
https://doaj.org/article/5d9fedf841fa43a684e48868afd73f1d
Ruthenium Photosensitizers for NIR PDT Require Lowest-Lying Triplet Intraligand (3IL) Excited States
Autor:
Liubov M. Lifshits, John A. Roque III, Elamparuthi Ramasamy, Randolph P. Thummel, Colin G. Cameron, Sherri A. McFarland
Publikováno v:
Journal of Photochemistry and Photobiology, Vol 8, Iss , Pp 100067- (2021)
A family of complexes of the type [Ru(tpbn)(IP-R)(4-pic)]Cl2 (tbpn=2,2′-(4-(tert‑butyl)pyridine-2,6-diyl)bis(1,8-napthyridine); 4-pic = 4-picoline; IP-R = imidazo[4,5-f][1,10]phenanthroline attached to an aromatic group R for 2–8 and H for 1) w
Externí odkaz:
https://doaj.org/article/192598318379494c8456464426f18c1f
Autor:
Drashti Shah, Menitte Eroy, John Fakhry, Azophi Moffat, Kevin Fritz, Houston D. Cole, Colin G. Cameron, Sherri A. McFarland, Girgis Obaid
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2426 (2022)
Osmium (Os)-based photosensitizers (PSs) exhibit unique broad, red-shifted absorption, favoring PDT activity at greater tissue depths. We recently reported on a potent Os(II) PS, rac-[Os(phen)2(IP-4T)](Cl)2 (ML18J03) with submicromolar hypoxia activi
Externí odkaz:
https://doaj.org/article/e21ca653a6b24aca8bb09c3f5d9ce9b5
Autor:
Prathyusha Konda, Liubov M. Lifshits, John A. Roque, Houston D. Cole, Colin G. Cameron, Sherri A. McFarland, Shashi Gujar
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
We report a new class of ruthenium (Ru)-based photosensitizers that induce potent cytotoxicity in melanoma cells following activation with NIR light. In addition to the direct cytotoxic effect, this Ru-based photodynamic therapy induces immunogenic c
Externí odkaz:
https://doaj.org/article/cd53397beefa46e8a7d7ee5b20571408
Autor:
Brett A. Duguay, Adrian Herod, Eric S. Pringle, Susan M. A. Monro, Marc Hetu, Colin G. Cameron, Sherri A. McFarland, Craig McCormick
Publikováno v:
Viruses, Vol 14, Iss 1, p 110 (2022)
Photodynamic inactivation (PDI) employs a photosensitizer, light, and oxygen to create a local burst of reactive oxygen species (ROS) that can inactivate microorganisms. The botanical extract PhytoQuinTM is a powerful photosensitizer with antimicrobi
Externí odkaz:
https://doaj.org/article/6a7e79cfefcb4b6681100f6fd0819f71
Autor:
Houston D. Cole, Menitte Eroy, John A. Roque, Ge Shi, Mina Guirguis, John Fakhry, Colin G. Cameron, Girgis Obaid, Sherri A. McFarland
Publikováno v:
Photochemistry and Photobiology. 99:751-760
Osmium (Os) based photosensitizers (PSs) are a unique class of nontetrapyrrolic metal-containing PSs that absorb red light. We recently reported a highly potent Os(II) PS, rac-[Os(phen)
Autor:
Avinash Chettri, Tingxiang Yang, Houston D. Cole, Ge Shi, Colin G. Cameron, Sherri A. McFarland, Benjamin Dietzek‐Ivanšić
Publikováno v:
Angewandte Chemie. 135
Autor:
Charles Edwin Webster, Nicholas A. Ward, Fengrui Qu, Olaitan E. Oladipupo, Jessica L. Gray, Robert W. Lamb, Matthew K. Thompson, Alexa R. DeRegnaucourt, Spenser R. Brown, Yifei Xu, Sherri A. McFarland, Colin G. Cameron, James Fletcher Hall, Marco Bonizzoni, Ambar B. Shrestha, Yonghyun Kim, Elizabeth T. Papish, Courtney M. Petersen
Publikováno v:
Photochem Photobiol
We report new ruthenium complexes bearing the lipophilic bathophenanthroline (BPhen) ligand and dihydroxybipyridine (dhbp) ligands which differ in the placement of the OH groups ([(BPhen)(2)Ru(n,n′-dhbp)]Cl(2) with n = 6 and 4 in 1(A) and 2(A), res