Výsledky vyhledávání - "Sherman Fong"

Comparison of chloral hydrate and pentobarbital sedation for pediatric echocardiography

Autor: Ira A. Parness, Sherman Fong, Rajesh Shenoy, Helen Ko, Madhusudan Ganigara, Shubhika Srivastava, Preeti Malik

Publikováno v: Echocardiography. 36:766-769

BACKGROUND In 2013, outpatient use of chloral hydrate (CH) was limited and other alternatives such as oral pentobarbital (PB) were explored to achieve conscious sedation in young children for transthoracic echocardiography (TTE). We aimed to assess e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cef8ed4a617bf94f2df24d410b86b26b
https://doi.org/10.1111/echo.14301

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Immune response in silico (IRIS): immune-specific genes identified from a compendium of microarray expression data

Autor: Daryl T. Baldwin, P M Williams, Wenjun Ouyang, Paulj. Godowski, Flavius Martin, M. van Lookeren Campagne, Alexander R. Abbas, Andrew C. Chan, A. Gurney, Hilary Clark, Sherman Fong, Y Ma

Publikováno v: Genes & Immunity. 6:319-331

Immune cell-specific expression is one indication of the importance of a gene's role in the immune response. We have compiled a compendium of microarray expression data for virtually all human genes from six key immune cell types and their activated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::745b959a8341caf52d0135dabc098b76
https://doi.org/10.1038/sj.gene.6364173

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Solid-phase synthesis of dual α4β1/α4β7 integrin antagonists: two scaffolds with overlapping pharmacophores

Autor: Susan M. Keating, James C. Marsters, Daniel P. Sutherlin, Sherman Fong, Lisa D. Caris, Kevin R Clark, Georgette Castanedo, John B. Nicholas, Henry Chiu, Fredrick C. Sailes, Maureen Beresini, David Y. Jackson, N. Dubree

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 12:2913-2917

Two structural classes of dual α4β1/α4β7 integrin antagonists were investigated via solid-phase parallel synthesis. Using an acylated amino acid backbone, lead compounds containing biphenylalanine or tyrosine carbamate scaffolds were optimized fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f3adcb9e0dd0192ba5beec71eb01a0d6
https://doi.org/10.1016/s0960-894x(02)00597-8

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Characterization of huJAM: evidence for involvement in cell-cell contact and tight junction regulation

Autor: Arthur J Huang, Randy J. Mrsny, Toni Klassen, Austin L. Gurney, Alane M. Gray, Holly L. Aaron, Jeffery Hooley, Richard A. DeMarco, Tony W. Liang, Sherman Fong, Daniel Tumas

Publikováno v: American Journal of Physiology-Cell Physiology. 279:C1733-C1743

Cell-cell interactions of the mucosal epithelia are important for the maintenance and establishment of epithelial barrier function. During events of inflammation, such cell-cell interactions are often disrupted, resulting in a leaky epithelial barrie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db64fa224a33ba379a9c999001550f4
https://doi.org/10.1152/ajpcell.2000.279.6.c1733

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Mucosal addressin cell adhesion molecule-1 (MAdCAM-1)

Autor: H H Chiu, Mark Renz, David Y. Jackson, Leonard G. Presta, S Jones, Sherman Fong, Anne M. Ryan

Publikováno v: Immunologic Research. 16:299-311

The integrin alpha 4 beta 7 and mucosal addressin cell adhesion molecule-1 (MAdCAM-1) are molecules involved in the normal recirculation of lymphocytes between the blood and the gastrointestinal tract. These molecules may play a complementary and sig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fdf7290157d38a3140cc91a6ea50c0b
https://doi.org/10.1007/bf02786396

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Structural requirements for adhesion of soluble recombinant murine vascular cell adhesion molecule-1 to alpha 4 beta 1

Autor: M E Renz, J Fox, H H Chiu, L G Presta, Sherman Fong, K J Kim, S Jones

Publikováno v: The Journal of Cell Biology

This study describes the identification of seven amino acid residues of the vascular cell adhesion molecule (VCAM-1) that influence binding to the alpha 4 beta 1 receptor. Using recombinant murine VCAM-1-IgG, which is bound by both mouse (WEHI 231) a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477a9dc501a22964c696bca6a275bd33
http://europepmc.org/articles/PMC2290915

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Homotypic leukocyte aggregation triggered by a monoclonal antibody specific for a novel epitope expressed by the integrin β1 subunit: Conversion of nonresponsive cells by transfecting human integrin α4 subunit cDNA

Autor: Mark Renz, John L. Bednarczyk, Margit C. Szabo, James N. Wygant, Laura Molinari-Storey, Bradley W. McIntyre, Sherman Fong

Publikováno v: Journal of Cellular Biochemistry. 51:465-478

The monoclonal antibody 33B6 was found to be specific for the beta 1 integrin subunit. Treatment of leukocytes with this antibody induced a vigorous homotypic aggregation that had similar physiologic conditions as aggregation induced by a monoclonal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::25a6c571d4c86dbe7dd7dd88ff607a00
https://doi.org/10.1002/jcb.2400510412

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Evidence supporting a role for cathepsin B in the generation of T cell antigenic epitopes of human growth hormone

Autor: Sherman Fong, Christopher Nelson, Christopher Grimley, Gillian Robin Bushell, William J. Henzel, Henry Chiu, John Burnier

Publikováno v: Molecular Immunology. 30:587-591

The elucidation of the enzymatic processing mechanism associated with the formation of antigenic peptide fragments that combine with MHC class II molecules is fundamental to our understanding of the immune system. We have investigated a structurally

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c34e5fe85f0c2546e4e8cc59c5481a5
https://doi.org/10.1016/0161-5890(93)90033-8

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Molecular Basis for the Cross-Reactive Idiotypes on Human Anti-Igg Autoantibodies (Rheumatoid Factors)

Autor: Frank R. Jirik, Sherman Fong, Gregg J. Silverman, Victor Radoux, Pojen P. Chen, Robert I. Fox, Thomas J. Kipps, Robert D. Goldfien, Dennis A. Carson

Publikováno v: Ciba Foundation Symposium 129-Autoimmunity and Autoimmune Disease ISBN: 9780470513484
Ciba Foundation Symposium 129-Autoimmunity and Autoimmune Disease

High titres of anti-IgG autoantibodies (rheumatoid factors, RF) are characteristic of patients with rheumatoid arthritis, Sjogren's syndrome, and mixed cryoglobulinaemia, and may contribute to immune complex formation and tissue damage. The monoclona

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f1a7d9f922a5919b1ab5825ced24f011
https://doi.org/10.1002/9780470513484.ch9

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Solid-phase synthesis of dual alpha4beta1/alpha4beta7 integrin antagonists: two scaffolds with overlapping pharmacophores

Autor: Georgette M, Castanedo, Fredrick C, Sailes, Nathan J P, Dubree, John B, Nicholas, Lisa, Caris, Kevin, Clark, Susan M, Keating, Maureen H, Beresini, Henry, Chiu, Sherman, Fong, James C, Marsters, David Y, Jackson, Daniel P, Sutherlin

Publikováno v: Bioorganicmedicinal chemistry letters. 12(20)

Two structural classes of dual alpha4beta1/alpha4beta7 integrin antagonists were investigated via solid-phase parallel synthesis. Using an acylated amino acid backbone, lead compounds containing biphenylalanine or tyrosine carbamate scaffolds were op

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::30e59cd619523076085eb4d97d674535
https://pubmed.ncbi.nlm.nih.gov/12270174

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