Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sherman E. Hasty"'
Publikováno v:
Antiviral Research. 13:139-149
The prophylactic efficacy of the broad-spectrum antiviral nucleoside analog ribavirin against flavivirus infection in non-human primates was investigated in a blinded, placebo-controlled study of rhesus monkeys infected with dengue virus. Both placeb
Publikováno v:
Vaccine. 10(1)
Two vaccinia-vectored candidate vaccines for haemorrhagic fever with renal syndrome were prepared by inserting cDNA, representing the medium (M) genome segment, or the M and the small (S) genome segments of Hantaan virus into the thymidine kinase gen
Autor:
P. L. Summers, Frank J. Malinoski, Robert McNair Scott, Charles H. Hoke, Jeanne Burrous, Doria R. Dubois, William H. Bancroft, Kenneth H. Eckels, Sherman E. Hasty, Thomas E. Simms
Publikováno v:
The American journal of tropical medicine and hygiene. 43(2)
To determine safety and immunogenicity, a single 0.5 ml dose of a monovalent live-attenuated dengue (DEN) 4 (341750 Carib) vaccine was given sc to 3 groups of flavivirus nonimmune volunteers in increasing concentrations. Two recipients received 10(3)
Autor:
Sherman E. Hasty, Lynn Rasmussen, Joel M. Dalrymple, Connie S. Schmaljohn, Ho Wang Lee, Pyung Woo Lee, Jiro Arikawa
Publikováno v:
Journal of General Virology. 69:1949-1955
Summary Viruses isolated from the blood of two Korean haemorrhagic fever patients were propagated in cell culture and compared to prototype Hantaan virus which was isolated from Apodemus mice. The antigenic properties of the human isolates were found
Autor:
David M. Robinson, Sherman E. Hasty
Publikováno v:
Applied Microbiology. 27:777-783
The attenuated M-44 strain of Coxiella burneti was heated to free it of adventitious agents that may have been present. Parallel titrations of the strain before and after heating indicated that the virulence for guinea pigs was markedly decreased. Gu
Autor:
Sherman E. Hasty, James W. LeDuc, Theodore F. Tsai, M. Brummer-Korvenkontio, Helen L. Regnery, C.-H. von Bonsdorff, Connie S. Schmaljohn, Joel M. Dalrymple, Antti Vaheri, Ho Wang Lee, Pyung Woo Lee, D. Goldgaber
Publikováno v:
Science. 227:1041-1044
Hemorrhagic fever with renal syndrome (HFRS) comprises a variety of clinically similar diseases of viral etiology that are endemic to and sporadically epidemic throughout the Eurasian continent and Japan. Although HFRS has not been reported in North
Publikováno v:
Journal of Infectious Diseases. 148:1005-1012
Hantaan virus, strain 76-118, was propagated to high titer in a clone of Vero cells, and infectious virions were successfully concentrated and purified. Infectivity and virus antigenic activity were closely associated with a virus particle that exhib
Autor:
Henry B. Bradford, Joseph B. McCormick, Charles T. Caraway, Robert Traub, Johnson Km, Oscar Medrano, Sally P. Bauer, D. Carleton Gajdusek, Clarence J. Gibbs, Pyung Woo Lee, Lauren R. Bagley, Louise M. McFarland, Donna R. Sasso, Herbert L. Amyx, Gregory A. Smith, Maryellen C. Franko, Theodore F. Tsai, George Soulie, James W. LeDuc, Richard Yanagihara, Sherman E. Hasty
Publikováno v:
New England Journal of Medicine. 307:623-625
Autor:
Helen H. Ramsburg, Neil H. Levitt, Harold W. Lupton, Sherman E. Hasty, Francis E. Cole, Patricia M. Repik
Publikováno v:
Vaccine. 4(3)
An attenuated chikungunya (CHIK) virus clone was developed for production of a live vaccine for human use. CHIK strain 15561 was subjected to 18 plaque-to-plaque passages in MRC-5 cultures before CHIK 181/clone 25 was selected as vaccine seed based o
Publikováno v:
The Journal of general virology. 67
The monovalent ionophore monensin, which interferes with cellular transport pathways, and the antibiotic tunicamycin, which prevents glycosylation of newly synthesized proteins, were used to examine Hantaan virus particle formation and polypeptide sy