In vitro and in silico evaluation of anti-quorum sensing activity of marine red seaweeds-Portieria hornemannii and Halymenia dilatata

Autor: Prakash Piruthivraj, B.R. Maha Swetha, A. Anita Margret, A. Sherlin Rosita, Parthasarathi Rengasamy, Rajapandiyan Krishnamoorthy, Mansour K. Gatasheh, Khalid Elfaki Ibrahim, Sekhu Ansari, Natesan Vijayakumar

Publikováno v: Journal of King Saud University: Science, Vol 36, Iss 6, Pp 103188- (2024)

The bacterial cell communicates from one cell to another by binding Auto-Inducers to specific receptors and their virulence factors, which are all products of their expression system. Therefore, this pathogenesis is controlled by disrupting the signa

Externí odkaz: https://doaj.org/article/a2cb185f65ba4878b5c90e9cda8cbd17

In-silico Analysis of Phytocompounds Identified by GC-MS from Moringa oleifera Leaves of Kolli Hills at Namakkal Against Colorectal Cancer

Autor: Sowmiya S, R. Jasmine, Sherlin Rosita A, Bharathi V, Keerthiga M

Publikováno v: International Journal of Life Science and Pharma Research.

Plants have been used for medicinal purposes long before the prehistoric period. The use of plants and natural substances to cure a wide range of human ailments has become increasingly popular due to the population explosion, insufficient drug supply

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::749838a601ca79b310c393d2a72092c8
https://doi.org/10.22376/ijlpr.2023.13.3.l38-l50

TRAF2 and NCK-Interacting Kinase Inhibitors for Colorectal Cancer: In Vitro and Theoretical Validations

Autor: Sherlin Rosita Arokiaraj, Karthikeyan Muthusamy, John Marshal Jayaraj, Manikandan Alagumuthu, Nargis Begum Tajuddin

Publikováno v: ACS Combinatorial Science. 22:608-616

TRAF2 and NCK-interacting kinase (TNIK) is a critical factor in colorectal cancer (CRC) proliferation mediated by Wnt signaling. We attempted to identify efficient TNIK inhibitors using computation...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60199ea80441bc2a65211cde0a90eee3
https://doi.org/10.1021/acscombsci.0c00027

Efficacy of Synthetic Organic Molecule Inhibitors of TRAF2 and NCK-Interacting Kinase (TNIK) Against Colorectal Cancer

Autor: Jesucastin Edward, Karthik Sudarsha, J. Jeyakanthan, A. Sherlin Rosita, Daniel A. Gideon

Publikováno v: Handbook of Oxidative Stress in Cancer: Therapeutic Aspects ISBN: 9789811612473
Handbook of Oxidative Stress in Cancer: Therapeutic Aspects ISBN: 9789811654213

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6400dc61b82695401701fc695959c389
https://doi.org/10.1007/978-981-16-1247-3_52-1

Molecular docking analysis reveals the functional inhibitory effect of Genistein and Quercetin on TMPRSS2: SARS-COV-2 cell entry facilitator spike protein

Autor: Reji Manjunathan, Vijayalakshmi Periyaswami, Kartik Mitra, Arokiaraj Sherlin Rosita, Medha Pandya, Jayaraman Selvaraj, Lokesh Ravi, Nalini Devarajan, Mukesh Doble

Publikováno v: BMC bioinformatics. 23(1)

Background The Transmembrane Serine Protease 2 (TMPRSS2) of human cell plays a significant role in proteolytic cleavage of SARS-Cov-2 coronavirus spike protein and subsequent priming to the receptor ACE2. Approaching TMPRSS2 as a therapeutic target f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd5dc31f7366fa3eac17c6db1639c40
https://pubmed.ncbi.nlm.nih.gov/35578172