Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Sherine F. Elsawa"'
Autor:
Stephan J. Matissek, Sherine F. Elsawa
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-20 (2020)
Abstract The transcription factor GLI3 is a member of the Hedgehog (Hh/HH) signaling pathway that can exist as a full length (Gli3-FL/GLI3-FL) or repressor (Gli3-R/GLI3-R) form. In response to HH activation, GLI3-FL regulates HH genes by targeting th
Externí odkaz:
https://doaj.org/article/adf82e5767ed48f2bd01b91b381d2f74
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11145 (2022)
Waldenström macroglobulinemia is an indolent, B-cell lymphoma without a known cure. The bone marrow microenvironment and cytokines both play key roles in Waldenström macroglobulinemia (WM) tumor progression. Only one FDA-approved drug exists for th
Externí odkaz:
https://doaj.org/article/a4de156d8eec49619776eb54893000a5
Autor:
Weiping Li, Shiv K. Gupta, Weiguo Han, Ryan A. Kundson, Sara Nelson, Darlene Knutson, Patricia T. Greipp, Sherine F. Elsawa, Eduardo M. Sotomayor, Mamta Gupta
Publikováno v:
Journal of Hematology & Oncology, Vol 12, Iss 1, Pp 1-13 (2019)
Abstract Double/triple-hit lymphomas (DHL/THL) account for 5–10% of diffuse large B cell lymphoma (DLBCL) with rearrangement of MYC and BCL2 and/or BCL6 resulting in MYC overexpression. Despite the poor prognosis of DHL, R-CHOP chemotherapy remains
Externí odkaz:
https://doaj.org/article/00911363edb0454eabfd03124bddd6dc
Autor:
Ava J. Boutilier, Sherine F. Elsawa
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 6995 (2021)
The M1/M2 macrophage paradigm plays a key role in tumor progression. M1 macrophages are historically regarded as anti-tumor, while M2-polarized macrophages, commonly deemed tumor-associated macrophages (TAMs), are contributors to many pro-tumorigenic
Externí odkaz:
https://doaj.org/article/756a60de027d4531bb154b1a4ac7e3f7
Autor:
David A. Jackson, Sherine F. Elsawa
Publikováno v:
Biomolecules, Vol 5, Iss 1, Pp 20-40 (2015)
Immunoglobulins are molecules produced by activated B cells and plasma cells in response to exposure to antigens. Upon antigen exposure, these molecules are secreted allowing the immune system to recognize and effectively respond to a myriad of patho
Externí odkaz:
https://doaj.org/article/bd042b3d5e2246c482d385af8adb5997
Autor:
Stephan J. Matissek, Mona Karbalivand, Weiguo Han, Ava Boutilier, Estefania Yzar-Garcia, Laura L. Kehoe, Devin Storm Gardner, Adam Hage, Krista Fleck, Vicki Jeffers, Ricardo Rajsbaum, Sherine F. Elsawa
Publikováno v:
Oncotarget. 13:944-959
The transcription factor GLI3 is a member of the GLI family and has been shown to be regulated by canonical hedgehog (HH) signaling through smoothened (SMO). Little is known about SMO-independent regulation of GLI3. Here, we identify TLR signaling as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::484658c118763b35b72ed76c99c5445f
https://doi.org/10.18632/oncotarget.28261
https://doi.org/10.18632/oncotarget.28261
Autor:
Mona Karbalivand, Luciana L. Almada, Stephen M. Ansell, Martin E. Fernandez-Zapico, Sherine F. Elsawa
Publikováno v:
Leukemia research. 116
Waldenström macroglobulinemia (WM) is a B cell lymphoma characterized by the overproduction of a monoclonal IgM antibody, a leading pathogenic feature of the disease. Current therapies are based on our knowledge at the signaling and genetic scale, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f5df76ee82935eab41505207f08169a
https://pubmed.ncbi.nlm.nih.gov/35462170
https://pubmed.ncbi.nlm.nih.gov/35462170
Autor:
Stephan J. Matissek, Mona Karbalivand, Weiguo Han, Ava Boutilier, Estefania Yzar-Garcia, Laura L. Kehoe, Devin Storm Gardner, Adam Hage, Krista Fleck, Vicki Jeffers, Ricardo Rajsbaum, Sherine F. Elsawa
Publikováno v:
Oncotarget. 14:448-448
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9935fcee496d816547e769165802251
https://doi.org/10.18632/oncotarget.28430
https://doi.org/10.18632/oncotarget.28430
Autor:
Ava J Boutilier, Anna D Metzler, Cameron E Banks, Sherine F Elsawa, Stephan Josef Matissek, Katja Koeppen
Publikováno v:
Blood. 140:9309-9309
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66728084404f16300b321656da1d80d7
https://doi.org/10.1182/blood-2022-163241
https://doi.org/10.1182/blood-2022-163241
Autor:
Sherine F. Elsawa, Ava J. Boutilier
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6995, p 6995 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
The M1/M2 macrophage paradigm plays a key role in tumor progression. M1 macrophages are historically regarded as anti-tumor, while M2-polarized macrophages, commonly deemed tumor-associated macrophages (TAMs), are contributors to many pro-tumorigenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb7f0fcf504eb4f13e1d506833e7c1c
https://www.mdpi.com/1422-0067/22/13/6995
https://www.mdpi.com/1422-0067/22/13/6995