Natural Prenylflavones from the Stem Bark of Artocarpus altilis: Promising Anticancer Agents for Oral Squamous Cell Carcinoma Targeting the Akt/mTOR/STAT‑3 Signaling Pathway

Autor: Maniyamma Aswathy, Dey Parama, Mangala Hegde, Sherin DR, Ravi S. Lankalapalli, Kokkuvayil Vasu Radhakrishnan, Ajaikumar B. Kunnumakkara

Publikováno v: ACS Omega, Vol 9, Iss 23, Pp 24252-24267 (2024)

Externí odkaz: https://doaj.org/article/62c4307b7f184f1581248d9acfa9afe7

Potential Drug Leads for SARS-CoV2 from Phytochemicals of Aerva lanata: An in silico approach

Autor: Sherin DR, Manojkumar TK

COVID-19 outbreak is the recently reported worldwide pandemic threat. As part of our interventions with molecular simulation approaches, we report the inhibitory effect of thirty compounds reported from the sacred plant Aerva lanata and compare their

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f4f57185f8c6c854385f14defdb0e59d
https://doi.org/10.22541/au.164865036.63209674/v1

Flavanoids from Saraca asoca- Ideal Medication for Breast Cancer: A Molecular Simulation Approach

Autor: Manojkumar Tk, Sherin Dr

Publikováno v: Biomedical Journal of Scientific & Technical Research. 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d2cb109b5f007b348153e7ef3f347705
https://doi.org/10.26717/bjstr.2017.01.000533

A comprehensive apoptotic assessment of niloticin in cervical cancer cells: a tirucallane-type triterpenoid from Aphanamixis polystachya (Wall.) Parker.

Autor: Joseph AG; CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Chemical Sciences and Technology Division (CSTD), Organic Chemistry Section Industrial Estate Thiruvananthapuram 695019 India radhu2005@gmail.com kkmaiti@niist.res.in.; Academy of Scientific and Innovative Research (AcSIR) Ghaziabad 201002 India., Biji M; CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Chemical Sciences and Technology Division (CSTD), Organic Chemistry Section Industrial Estate Thiruvananthapuram 695019 India radhu2005@gmail.com kkmaiti@niist.res.in.; Academy of Scientific and Innovative Research (AcSIR) Ghaziabad 201002 India., Murali VP; CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Chemical Sciences and Technology Division (CSTD), Organic Chemistry Section Industrial Estate Thiruvananthapuram 695019 India radhu2005@gmail.com kkmaiti@niist.res.in., Sherin DR; School of Digital Sciences, Kerala University of Digital Sciences, Innovation and Technology Thiruvananthapuram-695317 India., Valsan A; CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Chemical Sciences and Technology Division (CSTD), Organic Chemistry Section Industrial Estate Thiruvananthapuram 695019 India radhu2005@gmail.com kkmaiti@niist.res.in.; Academy of Scientific and Innovative Research (AcSIR) Ghaziabad 201002 India., Sukumaran VP; CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Chemical Sciences and Technology Division (CSTD), Organic Chemistry Section Industrial Estate Thiruvananthapuram 695019 India radhu2005@gmail.com kkmaiti@niist.res.in.; Academy of Scientific and Innovative Research (AcSIR) Ghaziabad 201002 India., Radhakrishnan KV; CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Chemical Sciences and Technology Division (CSTD), Organic Chemistry Section Industrial Estate Thiruvananthapuram 695019 India radhu2005@gmail.com kkmaiti@niist.res.in., Maiti KK; CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Chemical Sciences and Technology Division (CSTD), Organic Chemistry Section Industrial Estate Thiruvananthapuram 695019 India radhu2005@gmail.com kkmaiti@niist.res.in.

Publikováno v: RSC medicinal chemistry [RSC Med Chem] 2024 Aug 08. Date of Electronic Publication: 2024 Aug 08.

Pharmacological attenuation of melanoma by tryptanthrin pertains to the suppression of MITF-M through MEK/ERK signaling axis.

Autor: Shabna A; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, 695014, India., Antony J; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, 695014, India.; Department of Zoology, St. Thomas College, Palai, Kottayam, Kerala, India., Vijayakurup V; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, 695014, India.; Department of Anatomy and Cell Biology, Cancer and Genetics Research Complex, University of Florida, Gainesville, FL, 32610, USA., Saikia M; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, 695014, India., Liju VB; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, 695014, India.; The Shraga Segal Department of Microbiology Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, 84105, Beer Sheva, Israel., Retnakumari AP; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, 695014, India., Amrutha NA; Department of Biotechnology and Microbiology, Thalassery Campus, Kannur University, Kannur, Kerala, 670661, India., Alex VV; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, 695014, India., Swetha M; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, 695014, India., Aiswarya SU; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, 695014, India.; Department of Biotechnology, University of Calicut, Malappuram, Kerala, 673635, India., Jannet S; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, 695014, India., Unni US; KRIBS-BioNest, Third Campus of Rajiv Gandhi Centre for Biotechnology (RGCB) Kalamassery, Kochi, Kerala, India., Sundaram S; Department of Pathology, Government Medical College, Kottayam, Kerala, 686008, India., Sherin DR; Indian Institute of Information Technology and Management, Karyavattom, Kazhakkoottam, Kerala, 695581, India., Anto NP; The Shraga Segal Department of Microbiology Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, 84105, Beer Sheva, Israel., Bava SV; Department of Biotechnology, University of Calicut, Malappuram, Kerala, 673635, India., Chittalakkottu S; Department of Biotechnology and Microbiology, Thalassery Campus, Kannur University, Kannur, Kerala, 670661, India., Ran S; Department of Medical Microbiology, Immunology and Cell Biology, Southern Illinois University-School of Medicine, PO Box 19626, Springfield, IL, USA., Anto RJ; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, 695014, India. rjanto@rgcb.res.in.

Publikováno v: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2022 Aug 10; Vol. 79 (9), pp. 478. Date of Electronic Publication: 2022 Aug 10.