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pro vyhledávání: '"Sheril Daniel"'
The TPR2B Domain of the Hsp70/Hsp90 Organizing Protein (Hop) May Contribute Towards Its Dimerization
Publikováno v:
Protein & Peptide Letters. 16:402-407
The role of the TPR2B domain of Hop is as yet unknown. We have shown here by site directed mutagenesis and size exclusion chromatography for the first time that the TPR1 and TPR2B domains of Hop independently dimerized, and that the dimerization of T
Autor:
Sheril Daniel, Gregory L. Blatch, Peter Csermely, Victoria M. Longshaw, Graeme Bradley, Csaba Soti
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1783(6):1003-1014
The Hsp70–Hsp90 complex is implicated in the folding and regulation of numerous signaling proteins, and Hop, the Hsp70–Hsp90 Organizing Protein, facilitates the association of this multichaperone machinery. Phosphatase treatment of mouse cell ext
Publikováno v:
Water, Air, and Soil Pollution. 193:123-130
Stress responses can be measured at various levels of biological organization, from sub-organism through to ecosystem level. This study aimed to investigate stress protein induction as a sub-organism level stress response in two South African freshwa
Publikováno v:
Networking of Chaperones by Co-Chaperones ISBN: 9780387493084
Molecular chaperones and their co-chaperones are crucial for the facilitation of efficient protein folding, and prevention of denaturation and aggregation of nascent polypeptides. Hsp70/Hsp90 organizing protein (Hop), a co-chaperone of the two major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d76b494c1280d6e72fdcb78aafd17310
https://doi.org/10.1007/978-0-387-49310-7_3
https://doi.org/10.1007/978-0-387-49310-7_3
Publikováno v:
Journal of inorganic biochemistry. 98(2)
Curcumin, the major constituent of turmeric is a known, naturally occurring antioxidant. The present study examined the ability of this compound to protect against lead-induced damage to hippocampal cells of male Wistar rats, as well as lipid peroxid
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 27(1)
Alzheimer's disease (AD) is known to be characterised by a decrease in several brain neurotransmitters. However, the neurotransmitter, which decreases most markedly in this disorder, is acetylcholine (Ach). In addition, the biosynthetic enzyme for Ac