Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sheridan J. S. Carrington"'
Autor:
Christopher S. Hofmann, Karen J. Gregory, Colleen M. Niswender, Sheridan J. S. Carrington, Andrew N. Keller
Publikováno v:
RNA. 27:1220-1240
Metabotropic glutamate receptor 4 (mGlu4) is one of eight mGlu receptors within the Class C G protein-coupled receptor superfamily. mGlu4 is primarily localized to the presynaptic membrane of neurons where it functions as an auto and heteroreceptor c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c146cfbe89018a9aa22a22c88cd2b843
https://doi.org/10.1261/rna.078729.121
https://doi.org/10.1261/rna.078729.121
Autor:
Roger D. Cone, Michael J Litt, Sheridan J. S. Carrington, Isin Cakir, Masoud Ghamari-Langroudi, Taneisha Gillyard, Luis E. Gimenez, Erica J. P. Anderson
Publikováno v:
Journal of Molecular Endocrinology. 56:T157-T174
The melanocortin peptides derived from pro-opiomelanocortin (POMC) were originally understood in terms of the biological actions of α-melanocyte-stimulating hormone (α-MSH) on pigmentation and adrenocorticotrophic hormone on adrenocortical glucocor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a02b8b06e6e71f6a00d2c4b56e569c5
https://doi.org/10.1530/jme-16-0014
https://doi.org/10.1530/jme-16-0014
Autor:
Ciria C. Hernandez, Daniel R. Swale, Oluwatosin A. Aluko, Jerod S. Denton, Roger D. Cone, Sheridan J. S. Carrington
Publikováno v:
The Journal of biological chemistry. 293(46)
Kir7.1 is an inwardly rectifying potassium channel with important roles in the regulation of the membrane potential in retinal pigment epithelium, uterine smooth muscle, and hypothalamic neurons. Regulation of G protein–coupled inwardly rectifying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20715f15b2350e8142faf2a2a0b08d74
https://pubmed.ncbi.nlm.nih.gov/30257863
https://pubmed.ncbi.nlm.nih.gov/30257863
Autor:
Hyekyung P. Cho, Michael R. Wood, Kimberly M. Lovell, James C. Tarr, Christian Sevel, Sheridan J. S. Carrington, Douglas J. Sheffler, Uyen M. Le, Craig W. Lindsley, Colleen M. Niswender, P. Jeffrey Conn, Gregory J. Digby, Corey R. Hopkins
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:223-227
This letter describes the further exploration of two series of M(1) allosteric agonists, TBPB and VU0357017, previously reported from our lab. Within the TPBP scaffold, either electronic or steric perturbations to the central piperidine ring led to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cf1ae77a64e4fda985e731f54d0114c
https://doi.org/10.1016/j.bmcl.2012.10.132
https://doi.org/10.1016/j.bmcl.2012.10.132
Autor:
Sheridan J. S. Carrington, Nicholas D. P. Cosford, P. Jeffrey Conn, Colleen M. Niswender, Ryan D. Morrison, Douglas J. Sheffler, Anna L. Blobaum, Kiran Gogi, Shaun R. Stauffer, Joshua A. Bruner, Paige N. Vinson, J. Scott Daniels, Cody J. Wenthur, Mitchell Vamos, Craig W. Lindsley
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:3921-3925
Herein we report the discovery and SAR of a novel metabotropic glutamate receptor 3 (mGlu(3)) NAM probe (ML289) with 15-fold selectivity versus mGlu(2). The mGlu(3) NAM was discovered via a 'molecular switch' from a closely related, potent mGlu(5) po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084b68979b06bb1d3f771e787ac65e07
https://doi.org/10.1016/j.bmcl.2012.04.112
https://doi.org/10.1016/j.bmcl.2012.04.112