Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sherida M, de Leeuw"'
Autor:
Sherida M. de Leeuw, Tal Nuriel
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102779- (2024)
Summary: Studying cholesterol biology in the brain has been greatly hindered by the lack of adequate cholesterol visualization techniques. Here, we present a protocol for using a high-affinity cholesterol probe D4H∗-mCherry as a histology reagent i
Externí odkaz:
https://doaj.org/article/bebd1a4573994f6bbfe12bb843629367
Autor:
Joanna A. Korecka, Sebastien Talbot, Teresia M. Osborn, Sherida M. de Leeuw, Simon A. Levy, Eliza J. Ferrari, Alyssa Moskites, Elise Atkinson, Francine M. Jodelka, Anthony J. Hinrich, Michelle L. Hastings, Clifford J. Woolf, Penelope J. Hallett, Ole Isacson
Publikováno v:
Stem Cell Reports, Vol 12, Iss 1, Pp 29-41 (2019)
Summary: The Parkinson disease (PD) genetic LRRK2 gain-of-function mutations may relate to the ER pathological changes seen in PD patients at postmortem. Human induced pluripotent stem cell (iPSC)-derived neurons with the PD pathogenic LRRK2 G2019S m
Externí odkaz:
https://doaj.org/article/872a0bc4898b44ba96fb040e2470c7bb
Autor:
Sherida M. de Leeuw, Aron W.T. Kirschner, Karina Lindner, Ruslan Rust, Vanessa Budny, Witold E. Wolski, Anne-Claude Gavin, Roger M. Nitsch, Christian Tackenberg
Publikováno v:
Stem Cell Reports
Stem cell reports, Vol. 17, No 1 (2022) pp. 110-126
Stem Cell Reports, 17 (1)
Stem cell reports, Vol. 17, No 1 (2022) pp. 110-126
Stem Cell Reports, 17 (1)
Summary The apolipoprotein E4 (APOE4) variant is the strongest genetic risk factor for Alzheimer disease (AD), while the APOE2 allele is protective. A major question is how different APOE genotypes affect the physiology of astrocytes, the main APOE-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b48530d239704416200f45d747af230
http://europepmc.org/articles/PMC8758949
http://europepmc.org/articles/PMC8758949
Autor:
Stephanie Davaz, Vincent Milleret, Martin Ehrbar, Sherida M. de Leeuw, Debora Wanner, Anton F. Gietl, Christian Tackenberg
Publikováno v:
Journal of Neuroscience Methods, 360
Background Induced pluripotent stem cells (iPSCs) can be differentiated into virtually every desired cell type, offering significant potential for modeling human diseases in vitro. A disadvantage is that iPSC-derived cells represent an immature, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49f31642253d5edf39cefe057bfd9e98
https://hdl.handle.net/20.500.11850/491073
https://hdl.handle.net/20.500.11850/491073
Autor:
Karina Lindner, Katharina Beckenbauer, Larissa C. van Ek, Kevin Titeca, Sherida M. de Leeuw, Khader Awwad, Franziska Hanke, Alla V. Korepanova, Vladimir Rybin, Elizabeth Louise van der Kam, Eric G. Mohler, Christian Tackenberg, Viktor Lakics, Anne-Claude Gavin
Publikováno v:
Cell Reports, 38 (9)
Cell reports, Vol. 38, No 9 (2022) P. 110435
Cell reports, Vol. 38, No 9 (2022) P. 110435
Apolipoprotein E transports lipids and couples metabolism between astrocytes and neurons. The E4 variant (APOE4) affects these functions and represents a genetic predisposition for Alzheimer's disease, but the molecular mechanisms remain elusive. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac36e6a3530779122b54ff176b322c40
https://pubmed.ncbi.nlm.nih.gov/35235798
https://pubmed.ncbi.nlm.nih.gov/35235798
Autor:
Ole Isacson, Anthony J. Hinrich, Simon A. Levy, Elise Atkinson, Sherida M. de Leeuw, Eliza J. Ferrari, Alyssa Moskites, Sébastien Talbot, Clifford J. Woolf, Penelope J. Hallett, Teresia Osborn, Joanna A. Korecka, Francine M. Jodelka, Michelle L. Hastings
Publikováno v:
Stem Cell Reports, Vol 12, Iss 1, Pp 29-41 (2019)
Summary: The Parkinson disease (PD) genetic LRRK2 gain-of-function mutations may relate to the ER pathological changes seen in PD patients at postmortem. Human induced pluripotent stem cell (iPSC)-derived neurons with the PD pathogenic LRRK2 G2019S m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f993e77d09a81f7c9f359c3ea4c53bf5
http://www.sciencedirect.com/science/article/pii/S2213671118304909
http://www.sciencedirect.com/science/article/pii/S2213671118304909
Publikováno v:
Translational Neurodegeneration
Translational Neurodegeneration, Vol 8, Iss 1, Pp 1-13 (2019)
Translational Neurodegeneration, 8
Translational Neurodegeneration, Vol 8, Iss 1, Pp 1-13 (2019)
Translational Neurodegeneration, 8
Background Since the discovery of the induced pluripotent stem cell (iPSC) technique more than a decade ago, extensive progress has been made to develop clinically relevant cell culture systems. Alzheimer’s disease (AD) is the most common neurodege
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10edb82b05db2d473350483188023995
http://europepmc.org/articles/PMC6624934
http://europepmc.org/articles/PMC6624934
Autor:
Joanna A, Korecka, Sebastien, Talbot, Teresia M, Osborn, Sherida M, de Leeuw, Simon A, Levy, Eliza J, Ferrari, Alyssa, Moskites, Elise, Atkinson, Francine M, Jodelka, Anthony J, Hinrich, Michelle L, Hastings, Clifford J, Woolf, Penelope J, Hallett, Ole, Isacson
Publikováno v:
Stem Cell Reports
Summary The Parkinson disease (PD) genetic LRRK2 gain-of-function mutations may relate to the ER pathological changes seen in PD patients at postmortem. Human induced pluripotent stem cell (iPSC)-derived neurons with the PD pathogenic LRRK2 G2019S mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::73d3f53cb076d0d3c3693e4544876483
https://pubmed.ncbi.nlm.nih.gov/30595548
https://pubmed.ncbi.nlm.nih.gov/30595548