Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Sherene Min"'
Autor:
Samit R. Joshi, Disala Fernando, Stephanie Igwe, Litza McKenzie, Anu S. Krishnatry, Fiona Halliday, Joyce Zhan, Thomas J. Greene, Jianfeng Xu, Geraldine Ferron‐Brady, Max Lataillade, Sherene Min
Publikováno v:
Pharmacology Research & Perspectives, Vol 8, Iss 6, Pp n/a-n/a (2020)
Abstract Despite advances in HIV‐1 management with antiretroviral therapy, drug resistance and toxicities with multidrug regimens can result in treatment failure. Hence, there is a continuing demand for antiretroviral agents (ARVs) with novel mecha
Externí odkaz:
https://doaj.org/article/cb56c5de98f44634b415509c7f6e6e7f
Autor:
Javier Morales-Ramirez, Johannes R Bogner, Jean-Michel Molina, Johan Lombaard, Ira B Dicker, David A Stock, Michelle DeGrosky, Margaret Gartland, Teodora Pene Dumitrescu, Sherene Min, Cyril Llamoso, Samit R Joshi, Max Lataillade
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205368 (2018)
GSK3532795 (formerly known as BMS-955176) is a second-generation maturation inhibitor targeting a specific Gag cleavage site between capsid p24 and spacer peptide 1 of HIV-1. Study 205891 (previously AI468038) investigated the efficacy, safety, and d
Externí odkaz:
https://doaj.org/article/92a64a7f2d8649a182aebceafe35e801
Autor:
Ronald D'Amico, Santiago Cenoz Gomis, Riya Moodley, Rodica Van Solingen‐Ristea, Bryan Baugh, Erika Van Landuyt, Veerle Van Eygen, Sherene Min, Amy Cutrell, Caroline Foster, Daniella Chilton, Sabine D. Allard, Annemiek Ruiter
Publikováno v:
HIV Medicine. 24:202-211
OBJECTIVES: Physicians could request compassionate use of oral and long-acting (LA) cabotegravir + rilpivirine for people living with HIV-1 under a single-patient request programme supported by ViiV Healthcare and Janssen. Outcomes are reported. METH
Autor:
Max Lataillade, Lindsey Webster, Jianfeng Xu, Laurie Butcher, Eric Zimmerman, Samit R Joshi, Thomas J Greene, Theresa T. Pham, Mark Johnson, Teodora Pene Dumitrescu, Sherene Min
Publikováno v:
British Journal of Clinical Pharmacology
Aims GSK3640254, a novel, next-generation maturation inhibitor effective against a range of HIV polymorphisms with no cross-resistance to current antiretroviral therapy, could potentially be coadministered with dolutegravir as a 2-drug regimen. In th
Autor:
M Keith Rawlings, Emilio Letang, Romina Quercia, Richard Grove, Ralph DeMasi, Sherene Min, Vani Vannappagari, Andrew Zolopa, Jean van Wyk, Kimberly Smith
Publikováno v:
Open forum infectious diseases. 9(8)
Background In HIV clinical trials, proportions of Black and female participants achieving virologic suppression (VS) are often lower compared with White and male participants. As the antiretroviral therapy (ART) landscape continues to evolve, address
Autor:
Lindsey Webster, Sherene Min, Teodora Pene Dumitrescu, Eric Zimmerman, Max Lataillade, Thomas J Greene, Laurie Butcher, Fiona Halliday, Mark Johnson, Samit R Joshi, Theresa T. Pham, Jianfeng Xu
Publikováno v:
British journal of clinical pharmacology. 88(4)
Aims GSK3640254 is a next-generation maturation inhibitor likely to be coadministered with combined oral contraceptives in HIV-positive women. Methods This phase I, open-label, 1-way study assessed pharmacokinetic and pharmacodynamic interactions of
Autor:
Joyce Zhan, Max Lataillade, Sherene Min, Mark Johnson, Lindsey Webster, Samit R Joshi, Laurie Butcher, Eric Zimmerman, Teodora Pene Dumitrescu, Jianfeng Xu, Antonia M Davidson
Publikováno v:
Antimicrobial Agents and Chemotherapy
GSK3640254 is a next-generation maturation inhibitor that would likely be combined with standard antiretroviral agents to form a regimen of ≥2 fully active classes. This phase I, open-label, 2-period, 1-way study assessed potential pharmacokinetic
Autor:
Thomas J Greene, Sherene Min, Max Lataillade, Joyce Zhan, Samit R Joshi, Fiona Halliday, Stephanie Igwe, Geraldine Ferron-Brady, Litza McKenzie, Jianfeng Xu, Anu Shilpa Krishnatry, Disala Fernando
Publikováno v:
Pharmacology Research & Perspectives
Pharmacology Research & Perspectives, Vol 8, Iss 6, Pp n/a-n/a (2020)
Pharmacology Research & Perspectives, Vol 8, Iss 6, Pp n/a-n/a (2020)
Despite advances in HIV‐1 management with antiretroviral therapy, drug resistance and toxicities with multidrug regimens can result in treatment failure. Hence, there is a continuing demand for antiretroviral agents (ARVs) with novel mechanisms of
Autor:
Rolando M. Viani, Sherene Min, Ellen Townley, Edward P. Acosta, Debra Steimers, Carmelita Alvero, Andrew Wiznia, Rohan Hazra, Terry Fenton
Publikováno v:
Pediatric Infectious Disease Journal. 34:1207-1213
To assess the pharmacokinetics (PK), safety and efficacy of dolutegravir plus optimized background regimen in HIV-infected treatment-experienced adolescents.Children older than 12 to younger than 18 years received dolutegravir weight-based fixed dose
Autor:
Charles B. Hicks, Pablo Tebas, Catherine Granier, Sherene Min, Princy Kumar, Keith A. Pappa, Brian Wynne
Publikováno v:
AIDS (London, England)
Understanding long-term consequences of exposure to individual antiretroviral therapy (ART) components is important in making an initial HIV treatment selection. Initiation of ART is associated with a decrease in bone mineral density (BMD). This init