Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Shereen Salfity"'
Autor:
Apar Kishor Ganti, Surinder K. Batra, Moorthy P. Ponnusamy, Subodh M. Lele, Raghupathy Vengoji, Rama Krishna Nimmakayala, Prabin D. Majhi, Srustidhar Das, Abigail Thomas, Satyanarayana Rachagani, Parthasarathy Seshacharyulu, Shereen Salfity, Imayavaramban Lakshmanan
MUC16 incidence in lung cancer. A, MUC16 is overexpressed in a greater proportion of lung adenocarcinoma compared to other histological subtypes. B, Data from TCGA also shows that MUC16 is highly expressed in adenocarcinoma tissues than squamous carc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20142af2ff59959be7cd34aab7c53b41
https://doi.org/10.1158/1078-0432.22465764
https://doi.org/10.1158/1078-0432.22465764
Autor:
Apar Kishor Ganti, Surinder K. Batra, Moorthy P. Ponnusamy, Subodh M. Lele, Raghupathy Vengoji, Rama Krishna Nimmakayala, Prabin D. Majhi, Srustidhar Das, Abigail Thomas, Satyanarayana Rachagani, Parthasarathy Seshacharyulu, Shereen Salfity, Imayavaramban Lakshmanan
Supplementary Figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40146c24ed34a680121dd23f2cc7895b
https://doi.org/10.1158/1078-0432.22465767.v1
https://doi.org/10.1158/1078-0432.22465767.v1
Autor:
Apar Kishor Ganti, Surinder K. Batra, Moorthy P. Ponnusamy, Subodh M. Lele, Raghupathy Vengoji, Rama Krishna Nimmakayala, Prabin D. Majhi, Srustidhar Das, Abigail Thomas, Satyanarayana Rachagani, Parthasarathy Seshacharyulu, Shereen Salfity, Imayavaramban Lakshmanan
Stable knockdown of TSPYL5 in lung cancer cells. A, MUC16 expression was significantly elevated in cisplatin resistant cell line. To determine the TSPYL5 role in lung cancer, we stably knocked down TSPYL5 in H292 cells. B, Upon TSPYL5 knockdown, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beedff07cbbcee7afcabf7a93761b5d3
https://doi.org/10.1158/1078-0432.22465755.v1
https://doi.org/10.1158/1078-0432.22465755.v1
Autor:
Apar Kishor Ganti, Surinder K. Batra, Moorthy P. Ponnusamy, Subodh M. Lele, Raghupathy Vengoji, Rama Krishna Nimmakayala, Prabin D. Majhi, Srustidhar Das, Abigail Thomas, Satyanarayana Rachagani, Parthasarathy Seshacharyulu, Shereen Salfity, Imayavaramban Lakshmanan
Purpose: MUC16, a tumor biomarker and cell surface–associated mucin, is overexpressed in various cancers; however, its role in lung cancer pathogenesis is unknown. Here, we have explored the mechanistic role of MUC16 in lung cancer.Experimental Des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23abca2baba536b989fd8e25b7cd9f12
https://doi.org/10.1158/1078-0432.c.6526143
https://doi.org/10.1158/1078-0432.c.6526143
Autor:
Apar Kishor Ganti, Surinder K. Batra, Moorthy P. Ponnusamy, Subodh M. Lele, Raghupathy Vengoji, Rama Krishna Nimmakayala, Prabin D. Majhi, Srustidhar Das, Abigail Thomas, Satyanarayana Rachagani, Parthasarathy Seshacharyulu, Shereen Salfity, Imayavaramban Lakshmanan
Pharmacological inhibition of phospho JAK1/2 in lung cancer cells. A, Upon JAK1/2 inhibition by ruxolitinib, we observed decreased phosphorylation of STAT3 (Y705) but no change in STAT3 expression. B, Similar effect was also observed in MUC16-Cter ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3c92be42a991560bb05926c9f3c9a2
https://doi.org/10.1158/1078-0432.22465761.v1
https://doi.org/10.1158/1078-0432.22465761.v1
Autor:
Apar Kishor Ganti, Surinder K. Batra, Moorthy P. Ponnusamy, Subodh M. Lele, Raghupathy Vengoji, Rama Krishna Nimmakayala, Prabin D. Majhi, Srustidhar Das, Abigail Thomas, Satyanarayana Rachagani, Parthasarathy Seshacharyulu, Shereen Salfity, Imayavaramban Lakshmanan
Supplementary Figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc66a704708c41ce380eb60759cba162
https://doi.org/10.1158/1078-0432.22465767
https://doi.org/10.1158/1078-0432.22465767
Autor:
Apar Kishor Ganti, Surinder K. Batra, Moorthy P. Ponnusamy, Subodh M. Lele, Raghupathy Vengoji, Rama Krishna Nimmakayala, Prabin D. Majhi, Srustidhar Das, Abigail Thomas, Satyanarayana Rachagani, Parthasarathy Seshacharyulu, Shereen Salfity, Imayavaramban Lakshmanan
Chemoresistance properties of MUC16 and effect of cisplatin on apoptosis of MUC16 knockdown cells. A & B, MUC16 knockdown (H1975-shMUC16 seq1 and 2) cells were highly sensitive to cisplatin (A) and gemcitabine (B). C, The percentage of apoptotic cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40c71cacb30efeb377b9bc87e0ae2f5
https://doi.org/10.1158/1078-0432.22465758
https://doi.org/10.1158/1078-0432.22465758
Autor:
Parthasarathy Seshacharyulu, Satyanarayana Rachagani, Subodh M. Lele, Abigail Thomas, Srustidhar Das, Imayavaramban Lakshmanan, Raghupathy Vengoji, Apar Kishor Ganti, Shereen Salfity, Prabin D. Majhi, Moorthy P. Ponnusamy, Rama Krishna Nimmakayala, Surinder K. Batra
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 23(14)
Purpose: MUC16, a tumor biomarker and cell surface–associated mucin, is overexpressed in various cancers; however, its role in lung cancer pathogenesis is unknown. Here, we have explored the mechanistic role of MUC16 in lung cancer. Experimental De
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a600a80ef0b8b38fd9c326c5d601e7
https://pubmed.ncbi.nlm.nih.gov/28196872
https://pubmed.ncbi.nlm.nih.gov/28196872
