Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Shereen Sabbah"'
Publikováno v:
PLoS Pathogens, Vol 12, Iss 11, p e1006042 (2016)
Kaposi sarcoma-associated herpesvirus (KSHV) is linked with the development of Kaposi sarcoma and the B lymphocyte disorders primary effusion lymphoma (PEL) and multi-centric Castleman disease. T cell immunity limits KSHV infection and disease, howev
Externí odkaz:
https://doaj.org/article/13260334cce64992933330fb7cf3e711
Publikováno v:
Journal of Virology
Kaposi's sarcoma-associated herpesvirus (KSHV) has tropism for B lymphocytes, in which it establishes latency, and can also cause lymphoproliferative disorders of these cells manifesting as primary effusion lymphoma (PEL) and multicentric Castleman d
Autor:
Julie Douthwaite, Jacques Moisan, Cyril Privezentzev, Blagoje Soskic, Shereen Sabbah, Suzanne Cohen, Andie Collinson, Elizabeth England, Catherine Huntington, Ben Kemp, Li Zhuang, Suzanne Hudak, D. Gareth Rees, Debbie Goldberg, Chris Barton, Linda Chang, Inna Vainshtein, Meina Liang, Laurie Iciek, Philip Ambery, Mark Peakman, Tristan J. Vaughan, Tim I. M. Tree, David M. Sansom, Michael A. Bowen, Ralph R. Minter, Lutz Jermutus
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 199(5)
Autor:
Timothy Tree, Anthony E. Ting, Amy Raber, Robin R. Knight, Jef Pinxteren, James L. Reading, Robert J. Deans, Jennie H M Yang, Ania Skowera, Bart Vaes, Timothy E Allsopp, Sarah A. Busch, Shereen Sabbah
Publikováno v:
The Journal of Immunology. 190:4542-4552
A major goal of immunotherapy remains the control of pathogenic T cell responses that drive autoimmunity and allograft rejection. Adherent progenitor cells, including mesenchymal stromal cells (MSCs) and multipotent adult progenitor cells (MAPCs), re
Publikováno v:
Current Opinion in Organ Transplantation. 18:59-64
Purpose of review To evaluate the potential for mesenchymal stromal cells (MSCs) to regulate T-cell responses responsible for graft destruction following allogeneic islet transplantation (AIT). Recent findings Despite a high level of primary graft fu
Autor:
Alan B. Rickinson, Odette Chagoury, Rachel J. M. Abbott, Shereen Sabbah, Alison M. Leese, Heather M. Long, Eddie A. James, William W. Kwok, Gordon B. Ryan, Laura T. Morton
Publikováno v:
The Journal of Experimental Medicine
Characterization of the human EBV-specific CD4+ T cell response using MHC II tetramers reveals the latent EBV antigen response is more frequent than the lytic response with a delayed EBNA1 response that coincides with diminished cross-presentation.
Autor:
Tristan J. Vaughan, Linda Chang, Laurie Iciek, Timothy Tree, Philip Ambery, Elizabeth England, Inna Vainshtein, Debbie Goldberg, Catherine Huntington, Meina Liang, Suzanne Hudak, Suzanne Cohen, Chris Barton, Mark Peakman, Julie A. Douthwaite, Ben Kemp, Blagoje Soskic, Jacques Moisan, Li Zhuang, Ralph Minter, D. Gareth Rees, Andie Collinson, Shereen Sabbah, Michael A. Bowen, Lutz Jermutus, David M. Sansom, Cyril Privezentzev
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 198(1)
Affinity- and stability-engineered variants of CTLA4-Ig fusion molecules with enhanced pharmacokinetic profiles could yield improved therapies with the potential of higher efficacy and greater convenience to patients. In this study, to our knowledge,
Autor:
Shereen Sabbah, Christian Brander, Jianmin Zuo, Andrew D. Hislop, Katie L. Flanagan, Mohammad Mainul Ahasan, Sarah Rowland-Jones, Ya Jankey Jagne, Thushan I de Silva
Publikováno v:
Blood. 119:2083-2092
T-cell immunity is important for controlling Kaposi sarcoma–associated herpesvirus (KSHV) diseases such as the endothelial cell malignancy Kaposi sarcoma, or the B-cell malignancy, primary effusion lymphoma (PEL). However, little is known about KSH
Autor:
Andrew D. Hislop, Shereen Sabbah
Publikováno v:
Seminars in Cancer Biology. 18:416-422
Gammaherpesviruses are agents which have evolved to persist within the lymphoid system and many have oncogenic potential; studying gammaherpesvirus infections therefore has the potential to reveal much about the workings of the immune system and the
Autor:
Bart Vaes, Robert J. Deans, Nicholas Lehman, Anthony DiPiero, Anthony E. Ting, Fiona Carty, Shereen Sabbah, Nancy S Wang, Jen M Taggart, Thomas Hayday, Karen English, James L. Reading, Caroline M. Hull, Timothy Tree, Jef Pinxteren
T-cell depletion therapy is used to prevent acute allograft rejection, treat autoimmunity and create space for bone marrow or hematopoietic cell transplantation. The evolved response to T-cell loss is a transient increase in IL-7 that drives compensa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da9e68233200722aff14de17787ce563
https://europepmc.org/articles/PMC4817941/
https://europepmc.org/articles/PMC4817941/