Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Shenshen Hu"'
Autor:
Thomas Marron, Brett G M Hughes, Jason John Luke, Shenshen Hu, Suresh Mahabhashyam, Richard A Miller, William B Jones, Jaime R Merchan, Stephen B Willingham
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 12 (2022)
Background CD73 is widely expressed on immune cells playing a critical role in immunomodulatory functions including cell adhesion and migration, as a costimulatory molecule for T cells and in production of adenosine. The function of CD73 expressed on
Externí odkaz:
https://doaj.org/article/e01f803878c74d1d9d09ada0e739c0f0
Autor:
Igor Puzanov, Richard Miller, Jason Luke, Jeffrey Sosman, Thomas Marron, Brett Hughes, Abhishek Tripathi, Mehrdad Mobasher, Craig Hill, Shenshen Hu, Suresh Mahabhashyam, Kristen Marrone, Jaime Merchan, James Janc, Jenny Rudnick
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/03e6bccc86e0415f8d78ce6f1694289c
Autor:
Joshua Brody, Stephen Willingham, Richard Miller, Thomas Marron, Gerard Criner, Mehrdad Mobasher, Craig Hill, Shenshen Hu, Suresh Mahabhashyam
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/38d0ec6638e449f58996a29a7eec3d1d
Autor:
Adam R. Offenbacher, Shenshen Hu, Erin M. Poss, Cody A. M. Carr, Alexander D. Scouras, Daniil M. Prigozhin, Anthony T. Iavarone, Ali Palla, Tom Alber, James S. Fraser, Judith P. Klinman
Publikováno v:
ACS Central Science, Vol 3, Iss 6, Pp 570-579 (2017)
Externí odkaz:
https://doaj.org/article/9e694d41cae949cb94870565b513e6ae
Autor:
Jan Paulo T. Zaragoza, Adam R. Offenbacher, Shenshen Hu, Christine L. Gee, Zachary M. Firestein, Natalie Minnetian, Zhenyu Deng, Flora Fan, Anthony T. Iavarone, Judith P. Klinman
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The enzyme soybean lipoxygenase (SLO) provides a prototype for deep tunneling mechanisms in hydrogen transfer catalysis. This work combines room temperature X-ray studies with extended hydrogen–deuterium exchange experiments to define a catalytical
Autor:
Jan Paulo T. Zaragoza, Adam R. Offenbacher, Shenshen Hu, Christine L. Gee, Zachary M. Firestein, Natalie Minnetian, Zhenyu Deng, Flora Fan, Anthony T. Iavarone, Judith P. Klinman
The enzyme soybean lipoxygenase (SLO) provides a prototype for deep tunneling mechanisms in hydrogen transfer catalysis. This work combines room temperature X-ray studies with extended hydrogen deuterium exchange experiments to detect a radiating con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bac6f2887f20a341ea3b930c5657c441
https://doi.org/10.1101/2022.03.31.486235
https://doi.org/10.1101/2022.03.31.486235
Publikováno v:
J Biol Chem
Lipoxygenases are widespread enzymes found in virtually all eukaryotes, including fungi, and, more recently, in prokaryotes. These enzymes act on long-chain polyunsaturated fatty acid substrates (C18 to C20), raising questions regarding how the subst
Autor:
Richard A Miller, Jason John Luke, Shenshen Hu, Suresh Mahabhashyam, William B Jones, Thomas Marron, Jaime R Merchan, Brett G M Hughes, Stephen B Willingham
Publikováno v:
Journal for ImmunoTherapy of Cancer. 10:e005802
BackgroundCD73 is widely expressed on immune cells playing a critical role in immunomodulatory functions including cell adhesion and migration, as a costimulatory molecule for T cells and in production of adenosine. The function of CD73 expressed on
Autor:
Christian Tomaszewski, William B. Jones, Mehrdad Mobasher, James W. Janc, Richard A. Miller, Jorge Robles, Miriam L Cameron, Gerard J. Criner, Shenshen Hu, Stephen Willingham, Pramod Guru, Long Kwei, Philippe R. Bauer, Michael F. Waters, Suresh Mahabhashyam, Haider Mashhedi, Julián Olalla Sierra, Jenny A. Rudnick, J. Scott Overcash
Robust polyclonal humoral immune responses have the potential to generate a diverse set of antibodies to neutralize and eliminate viruses such as SARS-CoV-2 and protect against transmission, re-infection and the evolution of variants that evade immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72828493e8eb39cba2f97205aef7219a
https://doi.org/10.1101/2021.09.13.21263406
https://doi.org/10.1101/2021.09.13.21263406
Autor:
Richard K. Miller, Suresh Mahabhashyam, Thomas U. Marron, Joshua Brody, Shenshen Hu, Mehrdad Mobasher, Craig M. Hill, Stephen Willingham, Gerard J. Criner
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background CD73 is present on subsets of B and T cells and is involved in lymphocyte activation. CPI-006 is a humanized IgG1, Fcγ receptor deficient anti-CD73 that has agonistic properties. In vitro studies and ongoing cancer clinical trials show th