Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Shenqing Zhang"'
Autor:
Hengxu Mao, Yaoyun Kuang, Du Feng, Xiang Chen, Lin Lu, Wencheng Xia, Tingting Gan, Weimeng Huang, Wenyuan Guo, Hancun Yi, Yirong Yang, Zhuohua Wu, Wei Dai, Hui Sun, Jieyuan Wu, Rui Zhang, Shenqing Zhang, Xiuli Lin, Yuxuan Yong, Xinling Yang, Hongyan Li, Wenjun Wu, Xiaoyun Huang, Zhaoxiang Bian, Hoi Leong Xavier Wong, Xin-Lu Wang, Michael Poppell, Yi Ren, Cong Liu, Wen-Quan Zou, Shengdi Chen, Ping-Yi Xu
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-16 (2024)
Abstract Background Seed amplification assays (SAA) enable the amplification of pathological misfolded proteins, including α-synuclein (αSyn), in both tissue homogenates and body fluids of Parkinson’s disease (PD) patients. SAA involves repeated
Externí odkaz:
https://doaj.org/article/d23c5a987e634c22a6f7e6300ff16365
Publikováno v:
Fundamental Research, Vol 3, Iss 4, Pp 505-519 (2023)
Abnormal aggregation and accumulation of pathological amyloid proteins such as amyloid-β, Tau, and α-synuclein play key pathological roles and serve as histological hallmarks in different neurodegenerative diseases (NDs) such as Alzheimer's disease
Externí odkaz:
https://doaj.org/article/a8d08d8d0d174b5388290b377dfe7eb1
Autor:
Yichen Li, Jinge Gu, Chen Wang, Jiaojiao Hu, Shenqing Zhang, Cong Liu, Shengnan Zhang, Yanshan Fang, Dan Li
Publikováno v:
iScience, Vol 25, Iss 6, Pp 104356- (2022)
Summary: Hsp70 is a key molecular chaperone in the protein quality control system to safeguard protein homeostasis in cells. Previous studies have shown that Hsp70 chaperones TDP-43, a pathogenic protein associated with amyotrophic lateral sclerosis
Externí odkaz:
https://doaj.org/article/c9dfc1ff6efa4224bc7e12d66fecf8c3
Autor:
Yunpeng Sun, Shenqing Zhang, Jiaojiao Hu, Youqi Tao, Wencheng Xia, Jinge Gu, Yichen Li, Qin Cao, Dan Li, Cong Liu
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103701- (2022)
Summary: FUS is a multifunctional nuclear protein which undergoes liquid–liquid phase separation in response to stress and DNA damage. Dysregulation of FUS dynamic phase separation leads to formation of pathological fibril closely associated with n
Externí odkaz:
https://doaj.org/article/a528763ed6ea4ad5819176ff88b96b32
Autor:
Dong-Fei Ma1, Shenqing Zhang2,3, Si-Yao Xu1,4, Zi Huang1,4, Yuanxiao Tao5,6, Feiyang Chen2,3, Shengnan Zhang7,8, Dan Li2,3, Tongsheng Chen4, Cong Liu7,8 liulab@sioc.ac.cn, Ming Li1,5,6 mingli@iphy.ac.cn, Ying Lu1,5,6 yinglu@iphy.ac.cn
Publikováno v:
Science Advances. 10/11/2024, Vol. 10 Issue 41, p1-10. 10p.
Autor:
Kaien Liu, Youqi Tao, Qinyue Zhao, Wencheng Xia, Xiang Li, Shenqing Zhang, Yuxuan Yao, Huaijiang Xiang, Chao Han, Li Tan, Bo Sun, Dan Li, Ang Li, Cong Liu
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 8/27/2024, Vol. 121 Issue 35, p1-12, 30p
Autor:
Qi Wang, Zhouxian Li, Shenqing Zhang, Yichen Li, Yan Wang, Zheng Fang, Yanni Ma, Zhen Liu, Weibing Zhang, Dan Li, Cong Liu, Mingliang Ye
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(43)
Protein arginine methylation plays an important role in regulating protein functions in different cellular processes, and its dysregulation may lead to a variety of human diseases. Recently, arginine methylation was found to be involved in modulating
Autor:
Yun Fan, Qinyue Zhao, Wencheng Xia, Youqi Tao, Wenbo Yu, Mingjia Chen, Yiqi Liu, Jue Zhao, Yan Shen, Yunpeng Sun, Chenfang Si, Shenqing Zhang, Yaoyang Zhang, Wensheng Li, Cong Liu, Jian Wang, Dan Li
Publikováno v:
Cell Research. 32:585-588
Autor:
Yichen Li, Shuaiyao Lu, Jinge Gu, Wencheng Xia, Shengnan Zhang, Shenqing Zhang, Yan Wang, Chong Zhang, Yunpeng Sun, Jian Lei, Cong Liu, Zhaoming Su, Juntao Yang, Xiaozhong Peng, Dan Li
Publikováno v:
Protein & Cell. 13:602-614
The nucleocapsid (N) protein of SARS-CoV-2 has been reported to have a high ability of liquid-liquid phase separation, which enables its incorporation into stress granules (SGs) of host cells. However, whether SG invasion by N protein occurs in the s
Publikováno v:
Fundamental Research.