Siglec‐G Suppresses CD8+ T Cells Responses through Metabolic Rewiring and Can be Targeted to Enhance Tumor Immunotherapy

Autor: Shenhui Yin, Chunzhen Li, Xin Shen, Guanyu Yu, Likun Cui, Yunyang Wu, Yixian He, Shu Yu, Jie Chen, Shaoteng Lu, Guifang Qiu, Mengqi Song, Cheng Qian, Zui Zou, Yizhi Yu, Sheng Xu

Publikováno v: Advanced Science, Vol 11, Iss 45, Pp n/a-n/a (2024)

Abstract CD8+ T cells play a critical role in cancer immune‐surveillance and pathogen elimination. However, their effector function can be severely impaired by inhibitory receptors such as programmed death‐1 (PD‐1) and T cell immunoglobulin dom

Externí odkaz: https://doaj.org/article/5f022f9e70da450fa1f49680c294eff2

Siglec‐G Suppresses CD8⁺ T Cells Responses through Metabolic Rewiring and Can be Targeted to Enhance Tumor Immunotherapy.

Autor: Yin, Shenhui¹ (AUTHOR), Li, Chunzhen¹ (AUTHOR), Shen, Xin¹ (AUTHOR), Yu, Guanyu² (AUTHOR), Cui, Likun¹ (AUTHOR), Wu, Yunyang¹ (AUTHOR), He, Yixian¹ (AUTHOR), Yu, Shu¹ (AUTHOR), Chen, Jie¹ (AUTHOR), Lu, Shaoteng¹ (AUTHOR), Qiu, Guifang¹ (AUTHOR), Song, Mengqi¹ (AUTHOR), Qian, Cheng¹ (AUTHOR), Zou, Zui^3,4 (AUTHOR) zouzui@smmu.edu.cn, Yu, Yizhi¹ (AUTHOR) yuyz@immunol.org, Xu, Sheng¹ (AUTHOR) xusheng@immunol.org

Publikováno v: Advanced Science. 12/4/2024, Vol. 11 Issue 45, p1-17. 17p.

Researchers at Naval Medical University Target Melanoma (A Signature of Seven Hypoxia-related Lncrnas Is a Potential Biomarker for Predicting the Prognosis of Melanoma).

Publikováno v: Immunotherapy Weekly; 6/11/2024, p1122-1122, 1p