Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Shenhai Gong"'
Autor:
Dongping Li, Rongjuan Wei, Xianglong Zhang, Shenhai Gong, Meijuan Wan, Fangzhao Wang, Jiaxin Li, Meiling Chen, Ruofan Liu, Yantong Wan, Yinghao Hong, Zhenhua Zeng, Peng Gu, Zhang Wang, Kutty Selva Nandakumar, Yong Jiang, Hongwei Zhou, Peng Chen
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 7, Pp 3068-3085 (2024)
Sepsis progression is significantly associated with the disruption of gut eubiosis. However, the modulatory mechanisms of gut microbiota operating during sepsis are still unclear. Herein, we investigated how gut commensals impact sepsis development i
Externí odkaz:
https://doaj.org/article/e06ecacde56b49cbb689fd4680682fa1
Autor:
Fen Li, Na Qin, Yiqin Yu, Rui Dong, Xiaojie Li, Shenhai Gong, Zhenhua Zeng, Lin Huang, Hong Yang
Publikováno v:
Archives of Medical Science, Vol 20, Iss 3, Pp 984-996 (2024)
Introduction Recently, NLR family pyrin domain containing 3 (NLRP3) and pyroptosis have been reported to be involved in traumatic brain injury-induced acute lung injury (TBI-ALI). Studies have shown that triggering receptor expressed on myeloid cells
Externí odkaz:
https://doaj.org/article/a4bc04c9609c4a04b2dc49d061790c61
Autor:
Ping Qin, Yanru Li, Yangjing Su, Ze Wang, Rong Wu, Xiaoqi Liang, Yunong Zeng, Peiheng Guo, Zhichao Yu, Xintao Huang, Hong Yang, Zhenhua Zeng, Xiaoshan Zhao, Shenhai Gong, Jiaochan Han, Zhongqing Chen, Wei Xiao, Ali Chen
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Acetaminophen (APAP)-induced liver injury (AILI) is a pressing public health concern. Although evidence suggests that Bifidobacterium adolescentis (B. adolescentis) can be used to treat liver disease, it is unclear if it can prevent AILI. In
Externí odkaz:
https://doaj.org/article/744e579e7d444eafb646721bc9a0d5f8
Autor:
Shenhai Gong, Yunong Zeng, Ze Wang, Yanru Li, Rong Wu, Lei Li, Hongbin Hu, Ping Qin, Zhichao Yu, Xintao Huang, Peiheng Guo, Hong Yang, Yi He, Zhibin Zhao, Weidong Xiao, Xiaoshan Zhao, Lei Gao, Shumin Cai, Zhenhua Zeng
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Acetaminophen (APAP) overdose is a leading cause of drug-induced liver injury (DILI), with gender-specific differences in susceptibility. However, the mechanism underlying this phenomenon remains unclear. Our study reveals that the gender-specific di
Externí odkaz:
https://doaj.org/article/e1333a7e75224522889e1baa37929b5b
Autor:
Sheng An, Yi Yao, Hongbin Hu, Junjie Wu, Jiaxin Li, Lulan Li, Jie Wu, Maomao Sun, Zhiya Deng, Yaoyuan Zhang, Shenhai Gong, Qiaobing Huang, Zhongqing Chen, Zhenhua Zeng
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-13 (2023)
Abstract The increase of lactate is an independent risk factor for patients with sepsis-induced acute kidney injury (SAKI). However, whether elevated lactate directly promotes SAKI and its mechanism remain unclear. Here we revealed that downregulatio
Externí odkaz:
https://doaj.org/article/cc15e6bf19704d4da11c4499ab6efa44
Autor:
Zhuoen He, Yunong Zeng, Shuyu Li, Lizhen Lin, Ruisi Zhou, Fangzhao Wang, Wenjiao Yang, Yuhao Wu, Junhao Yang, Ali Chen, Zhang Wang, Hong Yang, Xiaoshan Zhao, Wei Xiao, Lei Li, Shenhai Gong
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Background and AimsDrug-induced liver injury (DILI) is a common cause of acute liver failure and represents a significant global public health problem. When discussing the gut-liver axis, although a great deal of research has focused on the role of g
Externí odkaz:
https://doaj.org/article/5766a386808543599d17a63cb988b622
Autor:
Shenhai Gong, Yinglin Feng, Yunong Zeng, Huanrui Zhang, Meiping Pan, Fangjie He, Rong Wu, Jingrui Chen, Jiuling Lu, Siyou Zhang, Songhua Yuan, Xia Chen
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-13 (2021)
Abstract Background Gut microbiota has been reported to be disrupted by cisplatin, as well as to modulate chemotherapy toxicity. However, the precise role of intestinal microbiota in the pathogenesis of cisplatin hepatotoxicity remains unknown. Metho
Externí odkaz:
https://doaj.org/article/96a7a884a5b74632b3fb030b10e69596
Autor:
Jinge Xin, Ning Sun, Hesong Wang, Hailin Ma, Bangyuan Wu, Lianxin Li, Yanyan Wang, Haonan Huang, Dong Zeng, Xiuquan Bai, Ali Chen, Shenhai Gong, Xueqin Ni, Yang Bai
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 228, Iss , Pp 113006- (2021)
Fluoride (F) exposure was widely reported to be associated with renal diseases. Since absorbed F enters the organism from drinking water mostly through the gastrointestinal tract, investigating changes of gut microbes may have profound implications f
Externí odkaz:
https://doaj.org/article/7fd218dbfee04c6e8607abf025f114f6
Autor:
Zhengzheng Yan, Boxuan Chen, Yuqiong Yang, Xinzhu Yi, Mingyuan Wei, Gertrude Ecklu-Mensah, Mary M. Buschmann, Haiyue Liu, Jingyuan Gao, Weijie Liang, Xiaomin Liu, Junhao Yang, Wei Ma, Zhenyu Liang, Fengyan Wang, Dandan Chen, Lingwei Wang, Weijuan Shi, Martin R. Stampfli, Pan Li, Shenhai Gong, Xia Chen, Wensheng Shu, Emad M. El-Omar, Jack A. Gilbert, Martin J. Blaser, Hongwei Zhou, Rongchang Chen, Zhang Wang
Publikováno v:
Nature Microbiology. 7:1361-1375
The mechanistic role of the airway microbiome in chronic obstructive pulmonary disease (COPD) remains largely unexplored. We present a landscape of airway microbe-host interactions in COPD through an in-depth profiling of the sputum metagenome, metab
Autor:
Weijie Liang, Yuqiong Yang, Shenhai Gong, Mingyuan Wei, Yingfei Ma, Ruipei Feng, Jingyuan Gao, Xiaomin Liu, Fuyi Tu, Wei Ma, Xinzhu Yi, Zhenyu Liang, Fengyan Wang, Lingwei Wang, Dandan Chen, Wensheng Shu, Bruce E. Miller, Ruth Tal-Singer, Gavin C. Donaldson, Jadwiga A. Wedzicha, Dave Singh, Tom M.A. Wilkinson, Christopher E. Brightling, Rongchang Chen, Nanshan Zhong, Zhang Wang
Publikováno v:
Cell Host & Microbe.