Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Shengyun Hu"'
Autor:
Yang Liu, Chen Chen, Jinbo Liu, Zhenqiang Sun, Bo Shao, Yanxin Xu, Pengyuan Dang, Shengyun Hu, Haifeng Sun, Chaoguan Wang, Junhong Hu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 5 (2024)
Background Accumulating evidence demonstrates that an increased tumor-associated macrophage abundance is often associated with poor prognosis in colorectal cancer (CRC). The mechanism underlying the effect of tumor-derived exosomes on M2 macrophage p
Externí odkaz:
https://doaj.org/article/94cfc39da1df4f1a8f47058d40b421e7
Autor:
Ming Yue, Shengyun Hu, Haifeng Sun, Baojing Tuo, Bin Jia, Chen Chen, Wenkang Wang, Jinbo Liu, Yang Liu, Zhenqiang Sun, Junhong Hu
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-20 (2023)
Abstract Tumor immunotherapy has transformed neoplastic disease management, yet low response rates and immune complications persist as major challenges. Extracellular vesicles including exosomes have emerged as therapeutic agents actively involved in
Externí odkaz:
https://doaj.org/article/bb9ab1d5114f40d187b5cd1d17d873a9
Autor:
Zhuang Chen, Wenkang Wang, Shengyun Hu, Haifeng Sun, Chen Chen, Zhiyong Zhang, Xinzhi Sun, Bin Jia, Junhong Hu, Chengzeng Wang, Yang Liu, Zhenqiang Sun
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108779- (2024)
Summary: Immune escape is identified as one of the reasons for the poor prognosis of colorectal cancer (CRC) patients. Circular RNAs are considered to promote tumor progression by mediating tumor immune escape. We discovered that higher expression of
Externí odkaz:
https://doaj.org/article/4d3e8c79a35b4ec597722aa7fc81b8c4
Autor:
Senbo Liu, Wenkang Wang, Shengyun Hu, Bin Jia, Baojing Tuo, Haifeng Sun, Qiming Wang, Yang Liu, Zhenqiang Sun
Publikováno v:
Cell Death and Disease, Vol 14, Iss 10, Pp 1-19 (2023)
Abstract Cancer immunotherapy has transformed traditional treatments, with immune checkpoint blockade being particularly prominent. However, immunotherapy has minimal benefit for patients in most types of cancer and is largely ineffective in some can
Externí odkaz:
https://doaj.org/article/e54a5af3efc1445fa1911843bdaa55b8
Autor:
Shengyun Hu, Kunkun Xia, Xiaobei Huang, Ye Zhao, Qingqing Zhang, Dongdong Huang, Weiyi Xu, Zhengju Chen, Chenfei Wang, Zhiyong Zhang
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Colorectal cancer (CRC) is a major cause of cancer-related deaths in humans, and effective treatments are still needed in clinical practice. Despite significant developments in anticancer drugs and inhibitors, their poor stability, water sol
Externí odkaz:
https://doaj.org/article/59d0033d43be4efe86ea22567de79f46
Autor:
Hao Zhang, Lin Liu, Jinbo Liu, Pengyuan Dang, Shengyun Hu, Weitang Yuan, Zhenqiang Sun, Yang Liu, Chengzeng Wang
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-23 (2023)
Abstract In recent years, tumor immunotherapy has made significant progress. However, tumor immunotherapy, particularly immune checkpoint inhibitors (e.g., PD-1/PD-L1 inhibitors), benefits only a tiny proportion of patients in solid cancers. The tumo
Externí odkaz:
https://doaj.org/article/ccc4faadf41f421d9bf6346f2edb939a
Autor:
Menghui Zhang, Shengyun Hu, Lin Liu, Pengyuan Dang, Yang Liu, Zhenqiang Sun, Bingbing Qiao, Chengzeng Wang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-20 (2023)
Abstract Exosome is a subgroup of extracellular vesicles, which has been serving as an efficient therapeutic tool for various diseases. Engineered exosomes are the sort of exosomes modified with surface decoration and internal therapeutic molecules.
Externí odkaz:
https://doaj.org/article/7d2aa9e38a544b11bc689c5554acee40
Publikováno v:
Cell Death and Disease, Vol 13, Iss 6, Pp 1-9 (2022)
Abstract Tumour immunity plays an important role in the development of cancer. Tumour immunotherapy is an important component of antitumour therapy. Exosomes, a type of extracellular vesicle, act as mediators of intercellular communication and molecu
Externí odkaz:
https://doaj.org/article/8c714908cba444b5a5e478160747c50c
Autor:
Kangkang Yang, Quanbo Zhou, Bingbing Qiao, Bo Shao, Shengyun Hu, Guixian Wang, Weitang Yuan, Zhenqiang Sun
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 983-997 (2022)
Exosomes are extracellular vesicles released by various cell types that perform various biological functions, mainly mediating communication between different cells, especially those active in cancer. Noncoding RNAs (ncRNAs), of which there are many
Externí odkaz:
https://doaj.org/article/8b3251ad660e445ea45ecfd33206ef63
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Clustered regularly interspaced short palindromic repeats/CRISPR-associated nuclease9 (CRISPR/Cas9) gene editing technology implements precise programming of the human genome through RNA guidance. At present, it has been widely used in the constructi
Externí odkaz:
https://doaj.org/article/d888f03426b4472ca4299e4d6335708d