Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Shengtian Zhao"'
Autor:
Yanan An, Chao Wang, Baozhen Fan, Ziqi Wang, Ying Li, Feng Kong, Chengjun Zhou, Zhang Cao, Mingxia Wang, Hui Sun, Shengtian Zhao, Yongfeng Gong
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113118- (2023)
Summary: Lipolysis-stimulated lipoprotein receptor (LSR) is a multi-functional protein that is best known for its roles in assembly of epithelial tricellular tight junctions and hepatic clearance of lipoproteins. Here, we investigated whether LSR con
Externí odkaz:
https://doaj.org/article/29d1911cb54344b0b93e48b7e124ba48
Autor:
Hui Sun, Hui Li, Jie Yan, Xiangdong Wang, Mengyuan Xu, Mingxia Wang, Baozhen Fan, Jieying Liu, Ninghua Lin, Xin Wang, Li Li, Shengtian Zhao, Yongfeng Gong
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Claudin-5 is a tight junction integral membrane protein, but it is also expressed in mature podocytes which lack tight junctions. Here the authors report that podocyte claudin-5 regulates WNT signaling activity by modulating WIF1 expression, and its
Externí odkaz:
https://doaj.org/article/3d73d61ba4cd4ce29ca7cc8b977fbb5f
Autor:
Ganggang Wang, Zheng Wang, Haiquan Lu, Zhiqun Zhao, Liqiang Guo, Feng Kong, Aizhen Wang, Shengtian Zhao
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: FRAS1 (Fraser syndrome protein 1), together with FREM1 (the Fras1-related extracellular matrix proteins 1) and FREM2, belonging to the FRAS1/FREM extracellular matrix protein family, are considered to play essential roles in renal organog
Externí odkaz:
https://doaj.org/article/69cbcf9523eb4f0ab11752d35c7c2288
Autor:
Haoran Wang, Keqin Zhang, Zheng Ruan, Dingqi Sun, Hui Zhang, Guiting Lin, Liangliang Hu, Shengtian Zhao, Qiang Fu
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/300708b52c07422ba9922b233e1cdf73
Publikováno v:
Pharmaceutical Biology, Vol 59, Iss 1, Pp 715-722 (2021)
Context Verbascoside (VB), which is found in many medicinal plant families, exhibits biological activities in various diseases. However, its effects on varicocele (VCL)-induced damage remain unknown. Objective To investigate the effects and mechanism
Externí odkaz:
https://doaj.org/article/5b7d0a0cfac944c880b5ce776677414f
Autor:
Xin Yu, Haitao Wang, Fang Xiao, Shan Jiang, Kailin Li, Qiuxing Chen, Gaosheng Wang, Feng Kong, Shengtian Zhao
Publikováno v:
Stem Cell Research, Vol 61, Iss , Pp 102751- (2022)
Glomerulopathy with fibronectin deposits (GFND) is an autosomal dominant kidney disease exhibiting microscopic hematuria, proteinuria, and hypertension that may lead to end-stage renal failure. In this study, using non-integrative episomal vectors an
Externí odkaz:
https://doaj.org/article/31c90ad46e0f46028bac7506c3bb331a
Autor:
Haoran Wang, Keqin Zhang, Zheng Ruan, Dingqi Sun, Hui Zhang, Guiting Lin, Liangliang Hu, Shengtian Zhao, Qiang Fu
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-11 (2020)
Abstract Background Intracavernous injection of mesenchymal stem cells (MSCs) is a promising method for diabetic mellitus-induced erectile dysfunction (DMED), but short survival time of MSCs in cavernous is a fatal defect for therapy. This study inve
Externí odkaz:
https://doaj.org/article/212c4b47e93246e296ba2ca5ef4036fa
Autor:
Kailin Li, Yuan Chen, Jianye Zhang, Yong Guan, Chao Sun, Xian Li, Xiaoshuai Xie, Denglu Zhang, Xin Yu, Tongyan Liu, Xufeng Zhang, Feng Kong, Shengtian Zhao
Publikováno v:
Renal Failure, Vol 42, Iss 1, Pp 89-97 (2020)
Background Embryonic metanephros is the mammalian renal anlagen, which is considered as a potential source for the regeneration of functional whole kidneys. Some studies reported that metanephros implanted into unilateral nephrectomized animals can d
Externí odkaz:
https://doaj.org/article/54657dbb410a48b68c046a5ba5ff85ea
Publikováno v:
Stem Cell Research, Vol 55, Iss , Pp 102453- (2021)
Robertsonian translocation between chromosomes 13 and 14 is reported to be a cause of male infertility. Here, we established an iPSC line (HRMSDUi001-A) from an azoospermic patient with 45,XY,der(13;14)(q10;q10) karyotype. Peripheral blood mononuclea
Externí odkaz:
https://doaj.org/article/de2ba8a917364c65b874ad62ae20c462
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Acute kidney injury (AKI) is a frequent clinical complication in critically ill patients, and it rapidly develops into renal failure with high morbidity and mortality. However, other than dialysis, no effective therapeutic interventions can offer rel
Externí odkaz:
https://doaj.org/article/ded2a87563b44164bdc76d0419d63c2a