Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Shengtao Yuan"'
Autor:
Shikai Gui, Wanli Yu, Jiabao Xie, Lunshan Peng, Yuanyuan Xiong, Zhen Song, Haitao Luo, Juexian Xiao, Shengtao Yuan, Zujue Cheng
Publikováno v:
Endocrine Connections, Vol 13, Iss 7, Pp 1-11 (2024)
Invasive pituitary neuroendocrine tumors (PitNETs) are the most prevalent types of intracranial and neuroendocrine tumors. Their aggressive growth and difficulty in complete resection result in a high recurrence rate. Cystine transporter solute carri
Externí odkaz:
https://doaj.org/article/d30ddbd28ee94ff4982e952d504ddcf8
Autor:
Xin Zhang, Jiajia Wang, Kun Tang, Yu Yang, Xiaowei Liu, Shengtao Yuan, Feng Guo, Lianjun Zhang, Kaili Ma
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-13 (2024)
Abstract The therapeutic efficacy of adoptive T cell therapy is largely restricted by reduced viability and dysfunction of CD8+ T cells. Continuous antigen stimulation disrupts the expansion, effector function, and metabolic fitness of CD8+ T cells,
Externí odkaz:
https://doaj.org/article/9ae066eaa4684b86867aea29068cfea3
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 176, Iss , Pp 116826- (2024)
Background: Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha (PIP5K1A) acts upstream of the Akt regulatory pathway and is abnormally expressed in many types of malignancies. However, the role and mechanism of PIP5K1A in colorectal cancer (CRC)
Externí odkaz:
https://doaj.org/article/d5deb7e7336b468ea5136ed22034c496
Autor:
Yang Liu, Ting Liu, Yuanzhang Zhou, Wenjie Li, Min Wang, Nanshan Song, Wenbin Zhang, Jingwei Jiang, Shengtao Yuan, Jianhua Ding, Gang Hu, Ming Lu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 2, Pp 662-677 (2023)
Alanine–serine–cysteine transporter 2 (ASCT2) is reported to participate in the progression of tumors and metabolic diseases. It is also considered to play a crucial role in the glutamate-glutamine shuttle of neuroglial network. However, it remai
Externí odkaz:
https://doaj.org/article/1401357c85f546649511a5744180d615
Autor:
Zhengrui Liu, Xiaodan Lyu, Jiaxu Chen, Benteng Zhang, Siman Xie, Yan Yuan, Li Sun, Shengtao Yuan, Hong Yu, Jian Ding, Mei Yang
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 224 (2024)
Background: Arnicolide C, which is isolated from Centipeda minima, has excellent antitumor effects. However, the potential impacts and related mechanisms of action of arnicolide C in breast cancer remain unknown. Methods: The viability of breast canc
Externí odkaz:
https://doaj.org/article/ef4100b8878d44be83b5aa187620c658
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Hepatocellular carcinoma (HCC) is the most common form of primary liver cancer, and it usually occurs following chronic liver disease. Although some progress has been made in the treatment of HCC, the prognosis of patients with advanced HCC is not op
Externí odkaz:
https://doaj.org/article/450fefafcf9e4632a6890c25f3ee75ac
Publikováno v:
World Journal of Surgical Oncology, Vol 20, Iss 1, Pp 1-9 (2022)
Abstract Background As reported, preclinical animal models differ greatly from the human body. The evaluation model may be the colossal obstacle for scientific research and anticancer drug development. Therefore, it is essential to propose efficient
Externí odkaz:
https://doaj.org/article/132ce0fe1c194eb1bbb678f648559b5a
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 2, Pp 558-580 (2022)
Hepatocellular carcinoma (HCC) is an aggressive human cancer with increasing incidence worldwide. Multiple efforts have been made to explore pharmaceutical therapies to treat HCC, such as targeted tyrosine kinase inhibitors, immune based therapies an
Externí odkaz:
https://doaj.org/article/2bcfef3596e44c83ae33b11e94d7c278
Autor:
Zhiqiang Wang, Zhibo Zhang, Yong Li, Li Sun, Dezhen Peng, Danyu Du, Xian Zhang, Luwei Han, Liwen Zhao, Ligong Lu, Hongzhi Du, Shengtao Yuan, Meixiao Zhan
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1526-1540 (2021)
Acute myeloid leukaemia (AML) is the most common form of acute leukaemia in adults, with increasing incidence with age and a generally poor prognosis. Almost 20% of AML patients express mutant isocitrate dehydrogenase 2 (mIDH2), which leads to the ac
Externí odkaz:
https://doaj.org/article/e33fabccea1f46cc8d7aca7e5c48fa8b
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4954 (2023)
Abnormal energy metabolism is a characteristic of tumor cells, and mitochondria are important components of tumor metabolic reprogramming. Mitochondria have gradually received the attention of scientists due to their important functions, such as prov
Externí odkaz:
https://doaj.org/article/205ab7b299bf44cb84162bb9c5661561