Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Shengshuang Chen"'
Autor:
Weilin Liao, Imran Khan, Guoxin Huang, Shengshuang Chen, Liang Liu, Wai Kit Leong, Xiao Ang Li, Jianlin Wu, W. L. Wendy Hsiao
Publikováno v:
Gut Microbes, Vol 13, Iss 1 (2021)
Colorectal cancer (CRC) ranks the third most common cancer type in both men and women. Besides the known genetic and epigenetic changes in the gut epithelial cells, we now know that disturbed gut microbes could also contribute to the onset and progre
Externí odkaz:
https://doaj.org/article/9ae6eab618f74a47aa03150b756b28d6
Publikováno v:
Medicinal Research Reviews. 42:1704-1734
Many drugs can bind directly to proteins or be bioactivated by metabolizing enzymes to form reactive metabolites (RMs) that rapidly bind to proteins to form drug-protein conjugates or metabolite-protein conjugates (DMPCs). The close relationship betw
Publikováno v:
Journal of Agricultural and Food Chemistry. 70:7085-7094
Flavonoid represents a significant class of secondary metabolites in Pu-erh tea with benefits to human health. For a rapid and complete discovery of such compounds, we established a data mining workflow that integrates software MS-DIAL, MS-FINDER, an
Publikováno v:
International Journal of Nanomedicine
Purpose Psoriasis is an inflammatory skin disease, where keratinocytes play pivotal roles in its pathogenesis. We prepared Celastrol Noisome hydrogel (Cel Nio gel) for the treatment of psoriasis and aimed to study its target site as well as the mecha
Publikováno v:
Phytochemistry Letters. 35:15-22
Limonoids are a kind of bioactive triterpenoids and mainly exist in the Meliaceae and Rutaceae plants. In this research, two new nimbolinin-type limonoids (1 and 2), one new trichilin-type limonoid (3), and one new havanensin-type limonoid (4), along
Autor:
Lili Zhang, Na Li, Shengshuang Chen, Xiqing Bian, Mohamed A. Farag, Yahui Ge, Jianbo Xiao, Jian-Lin Wu
Publikováno v:
TrAC Trends in Analytical Chemistry. 157:116818
Publikováno v:
Chemical research in toxicology. 34(11)
Covalent drugs are newly developed and proved to be successful therapies in past decades. However, the pharmacokinetics (PK) and pharmacodynamic (PD) studies of covalent drugs now ignore the drug and metabolite-protein modification. The low abundance
Autor:
W.L. Wendy Hsiao, Guoxin Huang, Jiao Bai, Shengshuang Chen, Jianbo Xiao, Weilin Liao, Shilin Gong, Jian-Lin Wu, Na Li
Publikováno v:
Food chemistry. 347
Probiotics can release many bioactive peptides that confer a myriad of benefits to the host health. However, exploring new bioactive peptides secreted by probiotics is hampered by lots of matrix-related interference peptides from the medium, and the
Autor:
Zaiying Wang, Zhan-Lin Li, Huaqi Pan, Shengshuang Chen, Hui-Ming Hua, Aihong Han, Jiao Bai, Xia-Nan Sang
Publikováno v:
Tetrahedron Letters. 58:740-743
A novel α-pyrone substituted spiciferone, lecanicillolide (1), was isolated along with structurally related known compounds 2–4 from the fungus Lecanicillium sp. PR-M-3. The structure of lecanicillolide was elucidated by UV, IR, HRESIMS, and NMR s
Publikováno v:
Chemical Research in Toxicology; 11/15/2021, Vol. 34 Issue 11, p2309-2318, 10p