Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Shengshuai Shan"'
Autor:
Shengshuai Shan, Abdulaziz H. Alanazi, Yohan Han, Duo Zhang, Yutao Liu, S. Priya Narayanan, Payaningal R. Somanath
Publikováno v:
Biomedicines, Vol 12, Iss 9, p 2053 (2024)
Diabetic retinopathy (DR) is a leading cause of blindness, yet its molecular mechanisms are unclear. Extracellular vesicles (EVs) contribute to dysfunction in DR, but the characteristics and functions of vitreous EVs are unclear. This study investiga
Externí odkaz:
https://doaj.org/article/a57e88ceca094a809a455712239e8e70
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
ObjectivesIn cardiovascular disease, previous studies have suggested young age as one of the reasons to explain the obesity paradox. This study attempts to provide a different opinion on this claim through unexpected findings.MethodsWe used a cross-s
Externí odkaz:
https://doaj.org/article/1a76924f3ce54e1f81689f620a95ace5
Publikováno v:
Life, Vol 14, Iss 7, p 883 (2024)
Background: Diabetic retinopathy (DR) is a leading cause of vision loss, with complex mechanisms. The study aimed to comprehensively explore vitreous humor of diabetic and non-diabetic individuals, paving the way for identifying the potential molecul
Externí odkaz:
https://doaj.org/article/6c730b961edf4a298d05b9913f35dc92
Autor:
Shengshuai Shan, Fang Liu, Edith Ford, Ruth B. Caldwell, S. Priya Narayanan, Payaningal R. Somanath
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 162, Iss , Pp 114714- (2023)
Proliferative retinopathies are the leading cause of irreversible blindness in all ages, and there is a critical need to identify novel therapies. We investigated the impact of triciribine (TCBN), a tricyclic nucleoside analog and a weak Akt inhibito
Externí odkaz:
https://doaj.org/article/4c5450ac96e4416eabf40d00605e6b7f
Publikováno v:
Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-9 (2020)
Abstract Background Dyslipidaemia and male sex are associated with gallbladder polyp (GBP) formation. However, the potential relation between the non-high-density lipoprotein-cholesterol-to-high-density lipoprotein-cholesterol (non-HDL-c/HDL-c) ratio
Externí odkaz:
https://doaj.org/article/59f7d2cd504344ef8b3ba98c0af4ccf0
Publikováno v:
Environmental Health, Vol 18, Iss 1, Pp 1-9 (2019)
Abstract Background The associations between maternal exposure to ambient PM2.5 during pregnancy and the risk of premature rupture of membranes (PROM) and preterm premature rupture of membranes (PPROM) are controversial. And no relevant study has bee
Externí odkaz:
https://doaj.org/article/016cc4a203164d9d8838e1fcd81a59a9
Autor:
Ping Gao, Pan Gao, Jinjing Zhao, Shengshuai Shan, Wei Luo, Orazio J. Slivano, Wei Zhang, Akiko Tabuchi, Scott A. LeMaire, Lars Maegdefessel, Ying H. Shen, Joseph M. Miano, Harold A. Singer, Xiaochun Long
Publikováno v:
Redox Biology, Vol 41, Iss , Pp 101903- (2021)
Abdominal aortic aneurysm (AAA) is a catastrophic disease with little effective therapy. Myocardin related transcription factor A (MRTFA, MKL1) is a multifaceted transcription factor, regulating diverse biological processes. However, a detailed under
Externí odkaz:
https://doaj.org/article/d02a080db3b2478899c5ec252816e38c
Publikováno v:
Lipids in Health and Disease, Vol 17, Iss 1, Pp 1-8 (2018)
Abstract Background The nonHDLc/HDLc ratio (in which nonHDLc is defined as total cholesterol minus HDLc) is positively associated with multiple dyslipidemia-related disorders. This study aimed to determine whether the nonHDLc/HDLc ratio is an indepen
Externí odkaz:
https://doaj.org/article/e848fe8f7653411d839cf3f3cefdb090
Transgenic Overexpression of IL-37 Protects Against Atherosclerosis and Strengthens Plaque Stability
Autor:
Jing Liu, Jibin Lin, Shaolin He, Chun Wu, Boyuan Wang, Jie Liu, Yanping Duan, Tianxiao Liu, Shengshuai Shan, Keping Yang, Nianguo Dong, Qingwei Ji, Kai Huang, Dazhu Li
Publikováno v:
Cellular Physiology and Biochemistry, Vol 45, Iss 3, Pp 1034-1050 (2018)
Background/Aims: Recently, studies have shown that interleukin-37 (IL-37) is involved in atherosclerosis-related diseases. However, the regulatory mechanisms of IL-37 in atherosclerosis remain unknown. This study aims to determine the role of IL-37 i
Externí odkaz:
https://doaj.org/article/7c758554e3c84bce905aa792708652fc
Publikováno v:
Journal of Medical Case Reports, Vol 11, Iss 1, Pp 1-7 (2017)
Abstract Background The coexistence of congenital left ventricular aneurysm and abnormal cardiac trabeculation with gene mutation has not been reported previously. Here, we report a case of coexisting congenital left ventricular aneurysm and prominen
Externí odkaz:
https://doaj.org/article/a0faf8aab4344fc8ab8b4e05867ede41