Zobrazeno 1 - 10
of 720
pro vyhledávání: '"Shengrong S"'
Publikováno v:
Revista de Investigación Clínica, Vol 76, Iss 4 (2024)
Background: Triple-negative breast cancer (TNBC) represents the most aggressive subtype of breast cancer (BC), characterized by a dismal prognosis. Dysregulated long non-coding RNA LINC01614 might be a potential biomarker for BC as previously reporte
Externí odkaz:
https://doaj.org/article/494dd28ab6f141d5a36fbd8f5c93d518
Autor:
Hang Lu MD, Xin Yu MD, Zhiliang Xu MD, Jingwen Deng MD, Master Jingwen Zhang MD, Yimin Zhang MD, Shengrong Sun MD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 23 (2024)
IGFBP6, a member of the IGF binding protein (IGFBP) family, is a specific inhibitor of insulin-like growth factor II (IGF-II) and can inhibit the growth of malignant tumors overexpressing IGF-II. Type 2 diabetes (T2D) is a basic disorder of glucose m
Externí odkaz:
https://doaj.org/article/c8dbb19dc3984bc690a2f473c2593883
Autor:
Chengwu Zhang, Yuanhong Zhou, Tao Chen, Sudhanshu Bhushan, Shengrong Sun, Panshi Zhang, Yalong Yang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Triple-negative breast cancer (TNBC) is currently the type of breast cancer with the worst prognosis; it lacks specific treatments, such as ER/PR antagonistic endocrine and anti-HER2 targeted therapies. Although immunotherapy with immune che
Externí odkaz:
https://doaj.org/article/300c09bfeff044ec90ba5df2e8192517
Autor:
Liantao Guo, Hong Cheng, Jianhua Liu, Weikang Shao, Lan Luo, Weijie Zheng, Shengrong Sun, Deguang Kong, Chuang Chen
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-13 (2024)
Abstract Background Breast cancer is the second leading cause of cancer-related death in women, and drug resistance during treatment is a major challenge. However, the mechanisms underlying drug resistance are not fully understood. Here we applied wh
Externí odkaz:
https://doaj.org/article/714bc638cd6444fd891306ed71929bdb
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Bladder cancer, a prevalent and heterogeneous malignancy, necessitates the discovery of pertinent biomarkers to enable personalized treatment. The mammalian target of rapamycin complex 1 (mTORC1), a pivotal regulator of cellular growth, meta
Externí odkaz:
https://doaj.org/article/50de7ad13a2240c4a0c687227f2bdcc7
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract Background Sine oculis homeobox homolog 1 (SIX1) is a transcription factor that has recently been identified as a crucial regulator of embryonic development and tumorigenesis. SIX1 is upregulated in different types of tumors, including breas
Externí odkaz:
https://doaj.org/article/9ab92a35fc0f4869b14403589cf01388
Autor:
Jingwen Zhang, Jingwen Deng, Jin Huang, Liye Mei, Ni Liao, Feng Yao, Cheng Lei, Shengrong Sun, Yimin Zhang
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
PurposeThe aim of this study was to investigate the value of a deep learning model (DLM) based on breast tumor ultrasound image segmentation in predicting pathological response to neoadjuvant chemotherapy (NAC) in breast cancer.MethodsThe dataset con
Externí odkaz:
https://doaj.org/article/2dfc5a9300494dab9bf7eadb49b66331
Autor:
Xin Yu, Ai-Ling Tian, Ping Wang, Juanjuan Li, Juan Wu, Bei Li, Zhou Liu, Siqing Liu, Zhijie Gao, Si Sun, Shengrong Sun, Yi Tu, Qi Wu
Publikováno v:
Cell Stress, Vol 7, Iss 4, Pp 20-33 (2023)
Macrolide antibiotics are widely used antibacterial agents that are associated with autophagy inhibition. This study aimed to investigate the association between macrolide antibi-otics and malignant tumors, as well as the effect on autophagy, reactiv
Externí odkaz:
https://doaj.org/article/9fa465f30f3148a785c8cd5ca98ecab8
Publikováno v:
Journal of Investigative Surgery, Vol 36, Iss 1 (2023)
Purpose Granulomatous lobular mastitis (GLM) is a benign inflammatory disease of the mammary gland with unknown etiology. Erythema nodosum (EN) is a rare, extramammary symptom of GLM. The purpose of this article was to investigate the clinical featur
Externí odkaz:
https://doaj.org/article/59128a9150b546d1a594302718be7b4f
Autor:
Liantao Guo, Deguang Kong, Jianhua Liu, Ling Zhan, Lan Luo, Weijie Zheng, Qingyuan Zheng, Chuang Chen, Shengrong Sun
Publikováno v:
Experimental Hematology & Oncology, Vol 12, Iss 1, Pp 1-27 (2023)
Abstract Breast cancer heterogeneity determines cancer progression, treatment effects, and prognosis. However, the precise mechanism for this heterogeneity remains unknown owing to its complexity. Here, we summarize the origins of breast cancer heter
Externí odkaz:
https://doaj.org/article/6d7332617b73497aa1cfa4022e682b07