Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Shengnan Shen"'
Publikováno v:
Journal of Materials Research and Technology, Vol 30, Iss , Pp 8740-8748 (2024)
Laser powder bed fusion (LPBF) is a cutting-edge metal additive manufacturing technology with promising applications in aerospace, biomedicine, and industrial automation. Its ability to fabricate intricate geometric shapes, achieve high surface preci
Externí odkaz:
https://doaj.org/article/c0adb8e630e34b95b0267d3edad4bfa5
Influence of shielding gas flow on pore evolution in AlSi10Mg/In718 alloy by laser powder bed fusion
Publikováno v:
Journal of Materials Research and Technology, Vol 30, Iss , Pp 8774-8791 (2024)
Laser powder bed fusion (LPBF) manufactured parts often suffer from porosity defects due to the rapid cooling and solidification processes, as well as the complex flow dynamics within the molten pool. These defects directly affect the mechanical prop
Externí odkaz:
https://doaj.org/article/3000f4d3e9984fe28d638c87855fef24
Autor:
Shengnan Shen, Qiwen Liao, Liwei Gu, Yongping Zhu, Yanqing Liu, Xinwei Zhang, Junzhe Zhang, Qiaoli Shi, Yuxiang Sun, Jigang Wang, Ligen Lin
Publikováno v:
Acta Materia Medica, Vol 3, Iss 1, Pp 31-45 (2024)
G protein-coupled receptors (GPCRs) are important, potential drug targets for the treatment of metabolic disorders, such as obesity. GPCRs crosstalk with several transducers, including heterotrimeric G proteins, GPCR kinases (GRKs), and β-arrestins.
Externí odkaz:
https://doaj.org/article/ff691603cecd4052bd61b8b36d583a93
Publikováno v:
MedComm, Vol 5, Iss 6, Pp n/a-n/a (2024)
Abstract Aging is a process that represents the accumulation of changes in organism overtime. In biological level, accumulations of molecular and cellular damage in aging lead to an increasing risk of diseases like sarcopenia. Sarcopenia reduces mobi
Externí odkaz:
https://doaj.org/article/24d8e8717d1242fd8b3109c38a7ab37e
Publikováno v:
Journal of Materials Research and Technology, Vol 28, Iss , Pp 605-614 (2024)
In view of the non-destructive and non-contact features, laser ultrasonic (LU) technology has long been the effective method to detect tiny defects for laser powder bed fusion (LPBF) additive manufactured specimens. Of larger concern is the variation
Externí odkaz:
https://doaj.org/article/3212f73d3a574b5598de34d5e8eb70de
Autor:
Peng Gao, Jianyou Wang, Chong Qiu, Huimin Zhang, Chen Wang, Ying Zhang, Peng Sun, Honglin Chen, Yin Kwan Wong, Jiayun Chen, Junzhe Zhang, Huan Tang, Qiaoli Shi, Yongping Zhu, Shengnan Shen, Guang Han, Chengchao Xu, Lingyun Dai, Jigang Wang
Publikováno v:
iMeta, Vol 3, Iss 2, Pp n/a-n/a (2024)
Abstract Malaria continues to pose a serious global health threat, and artemisinin remains the core drug for global malaria control. However, the situation of malaria resistance has become increasingly severe due to the emergence and spread of artemi
Externí odkaz:
https://doaj.org/article/7c8b8c7bcffb41ec812b9bb5d61b145a
Autor:
Qiuyan Guo, Minghong Zhao, Qixin Wang, Tianming Lu, Piao Luo, Lin Chen, Fei Xia, Huanhuan Pang, Shengnan Shen, Guangqing Cheng, Chuanhao Dai, Yuqing Meng, Tianyu Zhong, Chong Qiu, Jigang Wang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 173, Iss , Pp 116304- (2024)
Glycyrrhetinic acid (GA) shows great efficiency against non-small cell lung cancer (NSCLC), but the detailed mechanism is unclear, which has limited its clinical application. Herein, we investigated the potential targets of GA against NSCLC by activi
Externí odkaz:
https://doaj.org/article/f2973d33c9374da3990d3140034f8555
Publikováno v:
Journal of Materials Research and Technology, Vol 27, Iss , Pp 6376-6385 (2023)
Laser-directed energy deposition (L-DED) utilizes a high-power laser and coaxial powder feed to rapidly fabricate high-quality components with intricate structures. However, the complex interaction between the powder stream and laser beam is not yet
Externí odkaz:
https://doaj.org/article/06accdc551ad4fd3891c64f750d3ff07
Autor:
Qiuyan Guo, Qixin Wang, Jiayun Chen, Minghong Zhao, Tianming Lu, Zuchang Guo, Chen Wang, Yin Kwan Wong, Xueling He, Lin Chen, Wenjing Zhang, Chuanhao Dai, Shengnan Shen, Huanhuan Pang, Fei Xia, Chong Qiu, Daoyuan Xie, Jigang Wang
Publikováno v:
Research, Vol 7 (2024)
Rheumatoid arthritis (RA) is an autoimmune disease with features of synovial inflammation, cartilage erosion, bone destruction, and pain and is currently lacking a satisfactory treatment strategy. Dihydroartemisinin (DHA), the active metabolite of ar
Externí odkaz:
https://doaj.org/article/a39c62106e924b5caa4406cf42fb83e0
Publikováno v:
Molecules, Vol 28, Iss 23, p 7789 (2023)
Alkaloids represent a large family of natural products with diverse structures and bioactivities. These compounds and their derivatives have been widely used in clinics to treat various diseases. The endophytic Aspergillus is a filamentous fungus ren
Externí odkaz:
https://doaj.org/article/61516bd02528420a8f7e1cd2f9014e47