Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Shenglong Cao"'
Autor:
Shenglong Cao, Sudeep Shrestha, Jianru Li, Xiaobo Yu, Jingyin Chen, Feng Yan, Guangyu Ying, Chi Gu, Lin Wang, Gao Chen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-6 (2024)
Externí odkaz:
https://doaj.org/article/bcf7914d053c4103a3ccc42b2f885650
Autor:
Hanhai Zeng, Huaijun Chen, Min Li, Jianfeng Zhuang, Yucong Peng, Hang Zhou, Chaoran Xu, Qian Yu, Xiongjie Fu, Shenglong Cao, Jing Cai, Feng Yan, Gao Chen
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
Abstract Background Neuroinflammation and oxidative stress plays an important role in the pathogenesis of early brain injury (EBI) after subarachnoid hemorrhage (SAH). This study is the first to show that activation of autophagy protein nuclear recep
Externí odkaz:
https://doaj.org/article/d4653c589f4c45d483ca0e80f81a2ac4
Autor:
Yonghe Zheng, Linfeng Fan, Siqi Xia, Qiguo Yang, Zhihua Zhang, Huaijun Chen, Hanhai Zeng, Xiongjie Fu, Yucong Peng, Chaoran Xu, Kaibo Yu, Fuyi Liu, Shenglong Cao
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
AimThe complement cascade is activated and may play an important pathophysiologic role in brain injury after experimental intracerebral hemorrhage (ICH). However, the exact mechanism of specific complement components has not been well studied. This s
Externí odkaz:
https://doaj.org/article/6897474fe4d94742b36631ad3305e98e
Autor:
Hang Zhou, Libin Hu, Jianru Li, Wu Ruan, Yang Cao, Jianfeng Zhuang, Hangzhe Xu, Yucong Peng, Zhongyuan Zhang, Chaoran Xu, Qian Yu, Yin Li, Zhangqi Dou, Junwen Hu, Xinyan Wu, Xiaobo Yu, Chi Gu, Shenglong Cao, Feng Yan, Gao Chen
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-17 (2021)
Abstract Background Complex changes in the brain microenvironment following traumatic brain injury (TBI) can cause neurological impairments for which there are few efficacious therapeutic interventions. The reactivity of astrocytes is one of the keys
Externí odkaz:
https://doaj.org/article/9d21e5d648dd45b4990e27c594082166
Autor:
Yinghan Guo, Jiang Liu, Hanhai Zeng, Lingxin Cai, Tingting Wang, Xinyan Wu, Kaibo Yu, Yonghe Zheng, Huaijun Chen, Yucong Peng, Xiaobo Yu, Feng Yan, Shenglong Cao, Gao Chen
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundThe relationship between neutrophil to lymphocyte ratio (NLR) and poor outcome of aneurysmal subarachnoid hemorrhage (aSAH) is controversial. We aim to evaluate the relationship between NLR on admission and the poor outcome after aSAH.Metho
Externí odkaz:
https://doaj.org/article/6609dfd1bb5d45eaae73743f949c9b87
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Neurovascular units (NVUs) are basic functional units in the central nervous system and include neurons, astrocytes and vascular compartments. Ischemic stroke triggers not only neuronal damage, but also dissonance of intercellular crosstalk within th
Externí odkaz:
https://doaj.org/article/e58fa21d24f2451e82ec930c50eb1ba0
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
AimPrevious studies have proved that inhibiting inflammasome activation provides neuroprotection against early brain injury (EBI) after subarachnoid hemorrhage (SAH), which is mainly focused on the microglial inflammatory response, but the potential
Externí odkaz:
https://doaj.org/article/4f432496440f436f86f78d5cd157c5ed
Autor:
Yucong Peng, Jianfeng Zhuang, Guangyu Ying, Hanhai Zeng, Hang Zhou, Yang Cao, Huaijun Chen, Chaoran Xu, Xiongjie Fu, Hangzhe Xu, Jianru Li, Shenglong Cao, Jingyin Chen, Chi Gu, Feng Yan, Gao Chen
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-20 (2020)
Abstract Background Neuroinflammation is closely associated with the poor prognosis in subarachnoid hemorrhage (SAH) patients. This study was aimed to determine the role of stimulator of IFN genes (STING), an essential regulator to innate immunity, i
Externí odkaz:
https://doaj.org/article/c0dc07953fd740abb1e2fad8df00e887
Autor:
Xiaobo Yu, Xiongjie Fu, Xinyan Wu, Wenwen Tang, Lei Xu, Libin Hu, Chaoran Xu, Hang Zhou, Guoyang Zhou, Jianru Li, Shenglong Cao, Jiang Liu, Feng Yan, Lin Wang, Fuyi Liu, Gao Chen
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2022)
The gut microbiota plays a key role in regulating intracerebral hemorrhage (ICH)-induced neuroinflammation. The anti-neuroinflammatory effects of metformin (Met) have been reported in many central nervous system (CNS) diseases. However, whether Met r
Externí odkaz:
https://doaj.org/article/149fc42fa71147b78e9c811456d2dc12
Autor:
Hanhai Zeng, Bo Shao, Jianfeng Zhuang, Yucong Peng, Huaijun Chen, Qian Yu, Chaoran Xu, Xiongjie Fu, Hang Zhou, Yang Cao, Xiaobo Yu, Jianru Li, Shenglong Cao, Xiaoxiao Tan, Chi Gu, Feng Yan, Gao Chen
Publikováno v:
Journal of Functional Foods, Vol 72, Iss , Pp 104043- (2020)
Naringenin exhibits multiple pharmaceutical effects, while the effects of naringenin on early brain injury (EBI) after subarachnoid hemorrhage (SAH) and its underlying mechanism have not been well-studied yet. Here, male C57BL/6 mice were utilized to
Externí odkaz:
https://doaj.org/article/7d64e9609e224e44b37900efbf2b4c91