Zobrazeno 1 - 10
of 229
pro vyhledávání: '"Shengli, Xu"'
Autor:
Han Ping Loh, Farouq Bin Mahfut, Serene W Chen, Yuhan Huang, Jianxin Huo, Wei Zhang, Kong Peng Lam, Shengli Xu, Yuansheng Yang
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTT-cell-engaging bispecific antibodies (T-bsAbs) are promising immunotherapies for cancer treatment due to their capability of redirecting T-cells toward destroying tumor cells. Numerous T-bsAb formats have been developed, each with advantages
Externí odkaz:
https://doaj.org/article/8d90c44d609a46ee84e4e146feab623d
Autor:
Hengjun Huang, Yuxing Li, Gaopu Zhang, Gui-Xin Ruan, Zhijian Zhu, Wenjing Chen, Jia Zou, Rui Zhang, Jing Wang, Yu Ouyang, Shengli Xu, Xijun Ou
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
The germinal centre (GC) response is characterized by regulated production of high affinity, class-switched antibodies in response to T-cell dependent antigens. Here authors show that the GC response is not only regulated at the transcriptional and p
Externí odkaz:
https://doaj.org/article/9dd1d0516d374da390610427b32b3ae4
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Natural Killer (NK) cells are a type of innate lymphoid cells that play a crucial role in immunity by killing virally infected or tumor cells and secreting cytokines and chemokines. NK cell-mediated immunotherapy has emerged as a promising approach f
Externí odkaz:
https://doaj.org/article/2c9f247d1d2f47a99b7f3431d5c96bd2
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 4 (2023)
Cell therapy encompasses an expanding spectrum of cell-based regimes for the treatment of human ailments, such as the use of immune cells, in particular T cells, for combating tumors and the modulation of inflammatory immune responses. In this review
Externí odkaz:
https://doaj.org/article/bd38ac33a74547ae8340fa2a70491be7
Publikováno v:
Frontiers in Physics, Vol 11 (2023)
The direction-of-arrival (DOA) tracking of underwater targets is an important research topic in sonar signal processing. Considering that the underwater DOA tracking is a typical multi-target problem under unknown underwater environment with missing
Externí odkaz:
https://doaj.org/article/2186354f7bad4e0a8668d3fef72c799c
Publikováno v:
Cell Death and Disease, Vol 12, Iss 5, Pp 1-15 (2021)
Abstract Inflammatory bowel disease (IBD) is driven by multiple genetic and environmental risk factors. Patients with mutations in Bruton’s tyrosine kinase (BTK) is known to manifest high prevalence of intestinal disorders including IBD. Although B
Externí odkaz:
https://doaj.org/article/9bdc3c983c534270a4bd25ff43292385
Autor:
Qingkang Xu, Chen Chen, Zhefeng Xu, Feng Chen, Yongtao Yu, Xiang Hong, Shengli Xu, Jiajia Chen, Qin Ding, Hong Chen
Publikováno v:
Asian Journal of Urology, Vol 7, Iss 1, Pp 51-55 (2020)
Objective: To determine the feasibility of decellularized small intestinal submucosa (SIS) matrix in repairing ureteral strictures. Methods: Two patients with ureteral stenoses underwent ureteral reconstruction with SIS matrix at the Zhejiang Provinc
Externí odkaz:
https://doaj.org/article/605809fd44344e54a44ca250e2e0d646
Autor:
Gui-Xin Ruan, Yuxing Li, Wenjing Chen, Hengjun Huang, Rui Zhang, Changxu Chen, Kong-Peng Lam, Shengli Xu, Xijun Ou
Publikováno v:
Cell Reports, Vol 38, Iss 6, Pp 110338- (2022)
Summary: The spliceosome is a large ribonucleoprotein complex responsible for pre-mRNA splicing and genome stability maintenance. Disruption of the spliceosome activity may lead to developmental disorders and tumorigenesis. However, the physiological
Externí odkaz:
https://doaj.org/article/37745cba1d4f4c669ce1e89dd3a6fc14
Publikováno v:
International Journal of Aerospace Engineering, Vol 2022 (2022)
This paper is devoted to H∞ consensus design and online scheduling for homogeneous multiagent systems (MASs) with switching topologies via deep reinforcement learning. The model of homogeneous MASs with switching topologies is established based on
Externí odkaz:
https://doaj.org/article/f06d0628cb7947e299526711a60c2c5e
Autor:
Liting Hang, Ziyin Wang, Aaron S.C. Foo, Geraldine W.Y. Goh, Huey Ching Choong, John Thundyil, Shengli Xu, Kong-Peng Lam, Kah-Leong Lim
Publikováno v:
Neurobiology of Disease, Vol 161, Iss , Pp 105560- (2021)
Emerging studies implicate energy dysregulation as an underlying trigger for Parkinson's disease (PD), suggesting that a better understanding of the molecular pathways governing energy homeostasis could help elucidate therapeutic targets for the dise
Externí odkaz:
https://doaj.org/article/e681f29124b6458790dfeedd53c81d8a