Zobrazeno 1 - 10
of 187
pro vyhledávání: '"Shenglan, Liu"'
Autor:
Shenglan Liu, Wei Dai, Bei Jin, Feng Jiang, Hao Huang, Wen Hou, Jinxia Lan, Yanli Jin, Weijie Peng, Jingxuan Pan
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-24 (2024)
Abstract Metastasis remains the principal cause of cancer-related lethality despite advancements in cancer treatment. Dysfunctional epigenetic alterations are crucial in the metastatic cascade. Among these, super-enhancers (SEs), emerging as new epig
Externí odkaz:
https://doaj.org/article/c8b38a97b146474baae723425467e4e1
Publikováno v:
Zhongguo quanke yixue, Vol 26, Iss 31, Pp 3902-3907 (2023)
Background China's aging adults are increasing, and have increasing prevalence of multimorbidity and polypharmacy, leading to a high risk of drug-drug interactions and adverse drug reactions. There are few studies on potentially inappropriate medicat
Externí odkaz:
https://doaj.org/article/ef949b45938a4b06a941fa63f3ec3936
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-8 (2023)
Abstract Human body expressions convey emotional shifts and intentions of action and, in some cases, are even more effective than other emotion models. Despite many datasets of body expressions incorporating motion capture available, there is a lack
Externí odkaz:
https://doaj.org/article/9ef58e5bfb794b56b84716b21887b1f5
Autor:
Wei Dai, Caiyao Guo, Yu Wang, Yumei Li, Renjian Xie, Junhong Wu, Baole Yao, Dong Xie, Ling He, Yingying Li, Hao Huang, Yun Wang, Shenglan Liu
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Background Colorectal cancer (CRC) is one of the most prevalent types of malignant tumours. Metastasis is the leading cause of cancer-related mortality, with lung metastases accounting for 32.9% of all metastatic CRCs. However, since the bio
Externí odkaz:
https://doaj.org/article/911001d167b6412a8ab550a89e32408a
Autor:
Xiaopeng Peng, Ziwen Yu, Goverdhan Surineni, Bulian Deng, Meizhu Zhang, Chuan Li, Zhiqiang Sun, Wanyi Pan, Yao Liu, Shenglan Liu, Bin Yu, Jianjun Chen
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
In this study, a novel series of histone deacetylases 6 (HDAC6) inhibitors containing polycyclic aromatic rings were discovered and evaluated for their pharmacological activities. The most potent compound 10c exhibited high HDAC6 inhibitory activity
Externí odkaz:
https://doaj.org/article/88ad33862024465eabf4c987c34fa3eb
Autor:
Wen Hou, Lejun Huang, Hao Huang, Shenglan Liu, Wei Dai, Jianhong Tang, Xiangzhao Chen, Xiaolu Lu, Qisheng Zheng, Zhinuo Zhou, Ziyun Zhang, Jinxia Lan
Publikováno v:
Molecules, Vol 29, Iss 2, p 540 (2024)
Sinomenine, an isoquinoline alkaloid extracted from the roots and stems of Sinomenium acutum, has been extensively studied for its derivatives as bioactive agents. This review concentrates on the research advancements in the biological activities and
Externí odkaz:
https://doaj.org/article/3ea68b2ee08644ee9c2420976d6817db
Publikováno v:
IEEE Access, Vol 10, Pp 97835-97842 (2022)
The development of 3D sensors encourages researchers to process point cloud data directly. Point cloud data requires less memory but conveys more detailed 3D shape information. However, because of occlusion, sensing distance and other reasons, sensor
Externí odkaz:
https://doaj.org/article/fca82be902264a67b5e409071b50e5d4
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-7 (2021)
Externí odkaz:
https://doaj.org/article/b6f36191fda24c9d816b9419c66af2d5
Autor:
Wei Dai, Junhong Wu, Xiaopeng Peng, Wen Hou, Hao Huang, Qilai Cheng, Zhiping Liu, Walter Luyten, Liliane Schoofs, Jingfeng Zhou, Shenglan Liu
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 10, Pp n/a-n/a (2022)
Abstract Background Hepatic metastasis is the primary and direct cause of death in individuals with colorectal cancer (CRC) attribute to lack of effective therapeutic targets. The present study aimed to identify potential druggable candidate targets
Externí odkaz:
https://doaj.org/article/6c5cfe2e07204a19b6cd377fbda17070
Autor:
Wei Dai, Shenglan Liu, Shubo Wang, Li Zhao, Xiao Yang, Jingfeng Zhou, Yun Wang, Jing Zhang, Ping Zhang, Ke Ding, Yangqiu Li, Jingxuan Pan
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-16 (2021)
Abstract Colonization is believed a rate-limiting step of metastasis cascade. However, its underlying mechanism is not well understood. Uveal melanoma (UM), which is featured with single organ liver metastasis, may provide a simplified model for real
Externí odkaz:
https://doaj.org/article/850a7f385c8749a2b40757e94baacac0