Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Shengkai Xia"'
Autor:
Shengkai Xia, Wenzhe Duan, Mingxin Xu, Mengqi Li, Mengyi Tang, Song Wei, Manqing Lin, Encheng Li, Wenwen Liu, Qi Wang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-17 (2024)
Abstract Background Brain metastasis (BM) is common among cases of advanced non-small cell lung cancer (NSCLC) and is the leading cause of death for these patients. Mesothelin (MSLN), a tumor-associated antigen expressed in many solid tumors, has bee
Externí odkaz:
https://doaj.org/article/2576dde8f1c74c4f8d9f75d1687fb139
Autor:
Mengyi Tang, Mingxin Xu, Jian Wang, Ye Liu, Kun Liang, Yinuo Jin, Wenzhe Duan, Shengkai Xia, Guohui Li, Huiying Chu, Wenwen Liu, Qi Wang
Publikováno v:
Advanced Science, Vol 11, Iss 26, Pp n/a-n/a (2024)
Abstract Patients who have non‐small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) mutations are more prone to brain metastasis (BM) and poor prognosis. Previous studies showed that the tumor microenvironment of BM in these
Externí odkaz:
https://doaj.org/article/88e115f98f474a4ba26812cdc045acdc
Autor:
Wenzhe Duan, Wenwen Liu, Shengkai Xia, Yang Zhou, Mengyi Tang, Mingxin Xu, Manqing Lin, Xinyu Li, Qi Wang
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Resistance to pemetrexed (PEM), a rare chemotherapeutic agent that can efficiently cross the blood-brain barrier, limits the therapeutic efficacy for patients with lung cancer brain metastasis (BM). Aldo-keto reductase family 1 B1
Externí odkaz:
https://doaj.org/article/39a4bf8e81eb49fcbbd17cb0727bdc71
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 10, Pp n/a-n/a (2023)
Abstract Background Aggressive brain tumours, whether primary gliomas or secondary metastases, are characterised by hypervascularisation and are fatal. Recent research has emphasised the crucial involvement of endothelial cells (ECs) in all brain tum
Externí odkaz:
https://doaj.org/article/8254872674ed4cfb9d04770efe9dd666
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Glucose-regulating protein 78 (GRP78) is a molecular chaperone in the endoplasmic reticulum (ER) that promotes folding and assembly of proteins, controls the quality of proteins, and regulates ER stress signaling through Ca2+ binding to the
Externí odkaz:
https://doaj.org/article/319ae496bafe49b2b2a08c22b272f444
Autor:
Wenwen Liu, Yang Zhou, Wenzhe Duan, Jing Song, Song Wei, Shengkai Xia, Yingyan Wang, Xiaohui Du, Encheng Li, Caixia Ren, Wei Wang, Qimin Zhan, Qi Wang
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 9, Pp n/a-n/a (2021)
Abstract Background Platinum‐based chemotherapy is effective in inducing shrinkage of primary lung cancer lesions; however, it shows finite therapeutic efficacy in patients suffering from brain metastasis (BM). The intrinsic changes of BM cells, wh
Externí odkaz:
https://doaj.org/article/79caf3b7d343462394b0bdca71b518fb
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Anti-tumor drugs can effectively shrink the lesions of primary lung cancer; however, it has limited therapeutic effect on patients with brain metastasis (BM). A BM preclinical model based on a multi-organ microfluidic chip has been established profic
Externí odkaz:
https://doaj.org/article/c62f99dc0d3b40b3847d886f8f11427a
Background Pemetrexed (PEM), as a rare chemotherapeutic agent that can efficiently cross the blood-brain barrier, has profound implications for the treatment of patients with lung cancer brain metastasis (BM). However, resistance to PEM limits the th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::300c37994767760dd3b186b39153cf89
https://doi.org/10.21203/rs.3.rs-2331831/v1
https://doi.org/10.21203/rs.3.rs-2331831/v1
Publikováno v:
SSRN Electronic Journal.
Autor:
Encheng Li, Wenzhe Duan, Wei Wang, Jing Song, Yang Zhou, Shengkai Xia, Qi Wang, Qimin Zhan, Song Wei, Wenwen Liu, Caixia Ren, Yingyan Wang, Xiaohui Du
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 9, Pp n/a-n/a (2021)
Clinical and Translational Medicine
Clinical and Translational Medicine
Background Platinum‐based chemotherapy is effective in inducing shrinkage of primary lung cancer lesions; however, it shows finite therapeutic efficacy in patients suffering from brain metastasis (BM). The intrinsic changes of BM cells, which contr