Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Shenghui Mei"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Our study aims to explore the pharmacokinetics of valproic acid (VPA) in Chinese patients with epilepsy or after neurosurgery and establish a robust population pharmacokinetics (PPK) model. The PPK model was developed using nonlinear mixed-effects mo
Externí odkaz:
https://doaj.org/article/8c14744d3d5c4acaa05e96fdabafc752
Autor:
Xiao Ning, Lulu Wang, Jia-Sheng Wang, Jian Ji, Shaoming Jin, Jiadi Sun, Yongli Ye, Shenghui Mei, Yinzhi Zhang, Jin Cao, Xiulan Sun
Publikováno v:
Toxics, Vol 12, Iss 6, p 395 (2024)
Mycotoxins are a class of exogenous metabolites that are major contributors to foodborne diseases and pose a potential threat to human health. However, little attention has been paid to trace mycotoxin co-exposure situations in vivo. To address this,
Externí odkaz:
https://doaj.org/article/2ec884712fa14332a772cb1a08f2101d
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundObservational studies have found an increased risk of stroke in patients with spondyloarthritis, but the results are susceptible to reverse causality and confounders. Therefore, the study aimed to further explore the association between spo
Externí odkaz:
https://doaj.org/article/19f55ed8a20e4104810c818ad902bf2c
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
PurposeAcute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a dangerous symptom in patients with severe viral pneumonia. This study aims to comprehensively review the cooperation and influence of countries, institutions, authors and co
Externí odkaz:
https://doaj.org/article/4d98688a329f48a6b63f6c5c303e5fd9
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 19, Iss 1 (2023)
Vaccines may play an important role in cancer prevention. This bibliometric study in the field of vaccine and cancer prevention is designed to evaluate key research advances, identify existing deficiencies, and provide reference for future investigat
Externí odkaz:
https://doaj.org/article/412ce3563e4f4c1185aaea6ec1d7d428
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundCancer chemotherapy resistance is one of the most critical obstacles in cancer therapy. Since Warburg O first observed alterations in cancer metabolism in the 1950s, people gradually found tumor metabolism pathways play a fundamental role i
Externí odkaz:
https://doaj.org/article/1f469f8261cc44a9a7e564111ec963dd
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Objective: Vancomycin is commonly used in postoperative neurosurgical patients for empirical anti-infective treatment due to the low success rate of bacterial culture in cerebrospinal fluid (about 20%) and the high mortality of intracranial infection
Externí odkaz:
https://doaj.org/article/c7f4e9b9dbde45d1ab737e82c4160835
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-12 (2020)
Abstract Objectives The homeostasis of oral pathogenic bacteria and probiotics plays a crucial role in maintaining the well-being and healthy status of human host. Our previous study confirmed that imbalanced oral microbiota could impair mesenchymal
Externí odkaz:
https://doaj.org/article/b50007b2193e40a7b9a551666d549069
Autor:
Qiongyu Yan, Bin Zhang, Xi Ling, Bin Zhu, Shenghui Mei, Hua Yang, Dongjie Zhang, Jiping Huo, Zhigang Zhao
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Cytotoxic T-lymphocyte–associated protein 4 (CTLA-4) plays a pivotal role in regulating immune responses. It accumulates in intracellular compartments, translocates to the cell surface, and is rapidly internalized. However, the cytoplasmic function
Externí odkaz:
https://doaj.org/article/081f8918ed164f788b24f42903618eaa
Publikováno v:
Journal of Analytical Science and Technology, Vol 10, Iss 1, Pp 1-10 (2019)
Abstract Lamotrigine (LTG) and oxcarbazepine (OXC) are first-line drugs for epilepsy treatment. Their large pharmacokinetics variabilities and relations between efficacy and toxicity and blood plasma concentration require routine monitoring for dose
Externí odkaz:
https://doaj.org/article/8044d7e352bf45acb255560433b71735