Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sheng-Yuh Tang"'
Publikováno v:
Tetrahedron. 56:7885-7892
Prostaglandins are potent natural products which are involved in many biological processes. Here we report an improved synthesis of prostanoids by a three-component coupling approach using a soluble-polymer supported technique. Access to prostanoids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e24224cb1fb2003ded76f9fd780ff6c
https://doi.org/10.1016/s0040-4020(00)00707-9
https://doi.org/10.1016/s0040-4020(00)00707-9
Autor:
Sheng Yuh Tang, Salvino Joseph M, Richard Labaudiniere, Joseph J. Romano, Liang Ma, Morton George C, Marie Pierre Cherrier, Christopher Hulme, Steve Choi
Publikováno v:
Tetrahedron Letters. 41:1889-1893
This communication reveals novel applications of the CO2/MeOH reagent combination coupled with the UDC (Ugi/DeBOC/Cyclize) strategy. The Ugi five component condensation (5CC) affords carbamate protected amino-amides in good yield. When one of the sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22e2e5b1007c9a594dc08e2be046684f
https://doi.org/10.1016/s0040-4039(00)00053-8
https://doi.org/10.1016/s0040-4039(00)00053-8
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 725:103-112
The advent of combinatorial and parallel synthesis methodologies in drug discovery have necessitated the development of analytical techniques which permit high throughput quantitative analysis of mixtures of small organic molecules. High pressure liq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::012a5b18159cfdbd3f66a31e597cc83c
https://doi.org/10.1016/s0378-4347(98)00529-5
https://doi.org/10.1016/s0378-4347(98)00529-5
Publikováno v:
International Journal of Pharmaceutics. 121:95-105
RG 12915 (I) undergoes dechlorination and substitution in aqueous solutions when exposed to an artificial daylight fluorescent light. The free-radical photodecomposition exhibits apparent first-order kinetics at all concentrations and the reaction pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83cd24d92a8b2dd41f067eca66dc0af7
https://doi.org/10.1016/0378-5173(95)00014-a
https://doi.org/10.1016/0378-5173(95)00014-a
Autor:
Saul J. Needle, Amin Dilip, Sheng Yuh Tang, Glenda E. Bilder, Helen Galczenski, Linda Merkel, Donald Lewis, Camilo J. Rojas, Mark H. Perrone, Marie M. Gleason
Publikováno v:
Steroids. 60:475-483
Two separate enzymatic assays were developed in order to test the selectivity of inhibitors in cholesterol biosynthesis. One assay detects inhibition of delta 5.7-sterol delta 7-reductase, the enzyme involved in the conversion of 7-dehydrocholesterol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d83c061d9abd4b4fded4ca2974d64707
https://doi.org/10.1016/0039-128x(95)00054-t
https://doi.org/10.1016/0039-128x(95)00054-t
Autor:
Christopher Hulme, John Peng, Christopher J. Burns, Richard Labaudiniere, Sheng Yuh Tang, Isabelle Morize
Publikováno v:
ChemInform. 30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ac4a01daef080c796dca7181f467ba6
https://doi.org/10.1002/chin.199914182
https://doi.org/10.1002/chin.199914182
Autor:
Richard Labaudiniere, Christopher Hulme, Sheng Yuh Tang, Isabelle Morize, Christopher J. Burns, John Peng
Publikováno v:
The Journal of Organic Chemistry. 63:8021-8023
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e033754f2628b617e68f33e91930f0e
https://doi.org/10.1021/jo980622r
https://doi.org/10.1021/jo980622r
Autor:
Orton E, Jane Kline, Amy Dodd, Gerald McGeehan, Mathew Morrisette, Christopher J. Burns, Mason Helen J, Salvino Joseph M, Richard Labaudininiere, Groneberg Robert D, Terence Kiesow, Rose Mathew, Sheng-Yuh Tang, Ramesh Narensingh
Publikováno v:
Bioorganicmedicinal chemistry letters. 10(15)
Synthesis of an arylsulfone hydroxamate lead optimization library is presented. Biological activity of representative examples is given to demonstrate the value of this approach for lead optimization.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ea22e29f80b59c4d9c624824cfd8d8
https://pubmed.ncbi.nlm.nih.gov/10937713
https://pubmed.ncbi.nlm.nih.gov/10937713
Autor:
Vincent Windisch, Frank Deluccia, James J. Mencel, Marc Vuilhorgne, Sheng-Yuh Tang, Laurent Duhau, Frédéric Herman
Publikováno v:
Journal of pharmaceutical sciences. 86(3)
Salmon calcitonin (sCT), a 32-amino-acid peptide, is the active component in many pharmaceuticals used for the management of bone diseases. The degradation pathways of sCT were determined, and the structures of the major degradation products were ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c3c9e85a0b12beb1d963f6e7a83d1c
https://pubmed.ncbi.nlm.nih.gov/9050806
https://pubmed.ncbi.nlm.nih.gov/9050806
Autor:
F. F. Clerc, Marc Vuilhorgne, J. Becquart, Sheng-Yuh Tang, A. Van Dorsselaer, J. C. Holt, D. Faucher, F. Cuine, B. Monegier, C. Pourcet
Publikováno v:
Journal of chromatography. B, Biomedical applications. 662(2)
The conformity of two recombinant proteins (a von Willbrand factor fragment and human serum albumin, consisting of respectively 289 and 585 amino acids) has been examined by HPLC combined with mass spectrometry and microsequencing, on both intact mat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1744855a22183da86318e212494b7e1a
https://pubmed.ncbi.nlm.nih.gov/7719480
https://pubmed.ncbi.nlm.nih.gov/7719480