Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sheng-Xian Jiang"'
Publikováno v:
Microbial Cell Factories, Vol 20, Iss 1, Pp 1-13 (2021)
Abstract Background The polyene macrocyclic compound amphotericin B (AmB) is an important antifungal antibiotic for the clinical treatment of invasive fungal infections. To rationally guide the improvement of AmB production in the main producing stra
Externí odkaz:
https://doaj.org/article/537b7f04bf2f4169b14946c87bc907e5
Autor:
Bo Zhang, Yi-Teng Zhou, Sheng-Xian Jiang, Yu-Han Zhang, Kai Huang, Zhi-Qiang Liu, Yu-Guo Zheng
Publikováno v:
Microbial Cell Factories, Vol 19, Iss 1, Pp 1-12 (2020)
Abstract Background Amphotericin B (AmB) is widely used against fungal infection and produced mainly by Streptomyces nodosus. Various intracellular metabolites of S. nodosus were identified during AmB fermentation, and the key compounds that related
Externí odkaz:
https://doaj.org/article/748a3775d8874f1ba09daadd1c07e305
Autor:
Bo Zhang, Yu-Han Zhang, Yu Chen, Kai Chen, Sheng-Xian Jiang, Kai Huang, Zhi-Qiang Liu, Yu-Guo Zheng
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Amphotericin B is a clinically important polyene macrolide antibiotic with a broad-spectrum antifungal activity. In this work, the addition of key precursors and differential metabolites, combined with staged fermentation process control strategies,
Externí odkaz:
https://doaj.org/article/79e327e955414920a028de0f15ec77c0